Chandran U, Mehendale N, Patil S, Chaguturu R, Patwardhan B. Network Pharmacology. In: Patwardhan B, Chaguturu R, editors. Innovative approaches in drug discovery. 2017. p. 127–64. https://doi.org/10.1016/B978-0-12-801814-9.00005-2.

Noor F, Tahir ul Qamar M, Ashfaq UA, Albutti A, Alwashmi AS, Aljasir MA. Network pharmacology approach for medicinal plants: review and assessment. Pharmaceuticals. 2022;15(5):572. https://doi.org/10.3390/ph15050572.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Muthuramalingam P, Jeyasri R, Valliammai A, Selvaraj A, Karthika C, Gowrishankar S, Pandian SK, Ramesh M, Chen JT. Global multi-omics and systems pharmacological strategy unravel the multi-targeted therapeutic potential of natural bioactive molecules against COVID-19: an in silico approach. Genomics. 2020;112(6):4486–504. https://doi.org/10.1016/j.ygeno.2020.08.003.

Article  CAS  PubMed  Google Scholar 

Jeyasri R, Muthuramalingam P, Suba V, Ramesh M, Chen JT. Bacopa monnieri and their bioactive compounds inferred multi-target treatment strategy for neurological diseases: a cheminformatics and system pharmacology approach. Biomolecules. 2020;10(4): 536. https://doi.org/10.3390/biom10040536.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Adarshan S, Akassh S, Avinash K, Bharathkumar M, Muthuramalingam P, Shin H, Baskar V, Chen JT, Bhuvaneshwari V, Ramesh M. Transcriptomics, cheminformatics, and systems pharmacology strategies unveil the potential bioactives to combat COVID-19. Molecules. 2022;27(18): 5955. https://doi.org/10.3390/molecules27185955.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li R, Li Y, Liang X, Yang L, Su M, Lai KP. Network pharmacology and bioinformatics analyses identify intersection genes of niacin and COVID-19 as potential therapeutic targets. Brief Bioinform. 2021;22(2):1279–90. https://doi.org/10.1093/bib/bbaa300.

Article  CAS  PubMed  Google Scholar 

Aarthy M, Muthuramalingam P, Ramesh M, Singh SK. Unraveling the multi-targeted curative potential of bioactive molecules against cervical cancer through integrated omics and systems pharmacology approach. Sci Rep. 2022;12(1):1–19. https://doi.org/10.1038/s41598-022-18358-7.

Article  CAS  Google Scholar 

Zhang L, Ling Z, Hu Z, Meng G, Zhu X, Tang H. Huanglianjiedu Decoction as an effective treatment for oral squamous cell carcinoma based on network pharmacology and experimental validation. Cancer Cell Int. 2021;21(1):1–26. https://doi.org/10.1186/s12935-021-02201-6.

Article  CAS  Google Scholar 

Huang C, Zhan L. Network pharmacology identifies therapeutic targets and the mechanisms of glutathione action in ferroptosis occurring in oral cancer. Front Pharmacol. 2022;13: 851540. https://doi.org/10.3389/fphar.2022.851540.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hou F, Yu Z, Cheng Y, Liu Y, Liang S, Zhang F. Deciphering the pharmacological mechanisms of Scutellaria baicalensis Georgi on oral leukoplakia by combining network pharmacology, molecular docking and experimental evaluations. Phytomedicine. 2022;103: 154195. https://doi.org/10.1016/j.phymed.2022.154195.

Article  CAS  PubMed  Google Scholar 

Yu Z, Wu Y, Ma Y, Cheng Y, Song G, Zhang F. Systematic analysis of the mechanism of aged citrus peel (Chenpi) in oral squamous cell carcinoma treatment via network pharmacology, molecular docking and experimental validation. J Funct Foods. 2022;91:105012. https://doi.org/10.1016/j.jff.2022.105012.

Article  CAS  Google Scholar