Libby, P., Ridker, P. M. & Maseri, A. Inflammation and atherosclerosis. Circulation 105, 1135–1143 (2002).
Article CAS PubMed Google Scholar
Herrington, W., Lacey, B., Sherliker, P., Armitage, J. & Lewington, S. Epidemiology of atherosclerosis and the potential to reduce the global burden of atherothrombotic disease. Circ. Res. 118, 535–546 (2016).
Article CAS PubMed Google Scholar
Davignon, J. & Ganz, P. Role of endothelial dysfunction in atherosclerosis. Circulation 109, III27–III32 (2004).
Bennett, M. R., Sinha, S. & Owens, G. K. Vascular smooth muscle cells in atherosclerosis. Circ. Res. 118, 692–702 (2016).
Article CAS PubMed PubMed Central Google Scholar
Libby, P. The changing landscape of atherosclerosis. Nature 592, 524–533 (2021).
Article CAS PubMed Google Scholar
Libby, P., Ridker, P. M., Hansson, G. K. & Atherothrombosis, L. T. N. O. Inflammation in atherosclerosis: from pathophysiology to practice. J. Am. Coll. Cardiol. 54, 2129–2138 (2009).
Article CAS PubMed PubMed Central Google Scholar
Caro, C. G., Fitz-Gerald, J. M. & Schroter, R. C. Arterial wall shear and distribution of early atheroma in man. Nature 223, 1159–1160 (1969).
Article CAS PubMed Google Scholar
VanderLaan, P. A., Reardon, C. A. & Getz, G. S. Site specificity of atherosclerosis: site-selective responses to atherosclerotic modulators. Arterioscler Thromb. Vasc. Biol. 24, 12–22 (2004).
Article CAS PubMed Google Scholar
Tarbell, J. M. Mass transport in arteries and the localization of atherosclerosis. Annu. Rev. Biomed. Eng. 5, 79–118 (2003).
Article CAS PubMed Google Scholar
Fang, Y., Wu, D. & Birukov, K. G. Mechanosensing and mechanoregulation of endothelial cell functions. Compr. Physiol. 9, 873–904 (2019).
Article PubMed PubMed Central Google Scholar
Gallego-Colon, E., Daum, A. & Yosefy, C. Statins and PCSK9 inhibitors: a new lipid-lowering therapy. Eur. J. Pharmacol. 878, 173114 (2020).
Article CAS PubMed Google Scholar
Ridker, P. M. et al. Antiinflammatory therapy with canakinumab for atherosclerotic disease. N. Engl. J. Med. 377, 1119–1131 (2017).
Article CAS PubMed Google Scholar
Kwak, B. R. et al. Biomechanical factors in atherosclerosis: mechanisms and clinical implications. Eur. Heart J. 35, 3013–3020 (2014).
Article CAS PubMed PubMed Central Google Scholar
Tarbell, J. M., Shi, Z. D., Dunn, J. & Jo, H. Fluid mechanics, arterial disease, and gene expression. Annu. Rev. Fluid Mech. 46, 591–614 (2014).
Article PubMed PubMed Central Google Scholar
Andueza, A. et al. Endothelial reprogramming by disturbed flow revealed by single-cell RNA and chromatin accessibility study. Cell Rep. 33, 108491 (2020).
Article CAS PubMed PubMed Central Google Scholar
Chiu, J. J. & Chien, S. Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol. Rev. 91, 327–387 (2011).
Simmons, R. D., Kumar, S. & Jo, H. The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches. Arch. Biochem. Biophys. 591, 111–131 (2016).
Article CAS PubMed Google Scholar
Fernandez-Friera, L. et al. Prevalence, vascular distribution, and multiterritorial extent of subclinical atherosclerosis in a middle-aged cohort: the PESA (progression of early subclinical atherosclerosis) study. Circulation 131, 2104–2113 (2015).
Laclaustra, M. et al. Femoral and carotid subclinical atherosclerosis association with risk factors and coronary calcium: the AWHS study. J. Am. Coll. Cardiol. 67, 1263–1274 (2016).
Nam, D. et al. Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis. Am. J. Physiol. Heart Circ. Physiol. 297, H1535–H1543 (2009).
Article CAS PubMed PubMed Central Google Scholar
Cheng, C. et al. Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation 113, 2744–2753 (2006).
Kumar, S., Kang, D. W., Rezvan, A. & Jo, H. Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation. Lab. Invest. 97, 935–945 (2017).
Article CAS PubMed PubMed Central Google Scholar
Kim, C. W. et al. Disturbed flow promotes arterial stiffening through thrombospondin-1. Circulation 136, 1217–1232 (2017).
Article CAS PubMed PubMed Central Google Scholar
Kuhlmann, M. T. et al. Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice. J. Vis. Exp. https://doi.org/10.3791/3308 (2012).
Article PubMed PubMed Central Google Scholar
Tang, D., Geng, F., Yu, C. & Zhang, R. Recent application of zebrafish models in atherosclerosis research. Front. Cell Dev. Biol. 9, 643697 (2021).
Article PubMed PubMed Central Google Scholar
Schlegel, A. Zebrafish models for dyslipidemia and atherosclerosis research. Front. Endocrinol. 7, 159 (2016).
Baek, K. I. et al. Vascular injury in the zebrafish tail modulates blood flow and peak wall shear stress to restore embryonic circular network. Front. Cardiovasc. Med. 9, 841101 (2022).
Article CAS PubMed PubMed Central Google Scholar
Hsu, J. J. et al. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI Insight 4, e124460 (2019).
Article PubMed Central Google Scholar
Lee, J. et al. 4-Dimensional light-modulation of cardiac trabeculation. J. Clin. Investig. 126, 1679–1690 (2016).
Article PubMed PubMed Central Google Scholar
Lee, J. et al. Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation. JCI Insight https://doi.org/10.1172/jci.insight.96672 (2018).
Article PubMed PubMed Central Google Scholar
Baek, K. I. et al. Flow-responsive vascular endothelial growth factor receptor-protein kinase C isoform epsilon signaling mediates glycolytic metabolites for vascular repair. Antioxid. Redox Signal. 28, 31–43 (2018).
Article CAS PubMed PubMed Central Google Scholar
Dewey, C. F. Jr., Bussolari, S. R., Gimbrone, M. A. Jr. & Davies, P. F. The dynamic response of vascular endothelial cells to fluid shear stress. J. Biomech. Eng. 103, 177–185 (1981).
Lawrence, M. B., McIntire, L. V. & Eskin, S. G. Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion. Blood 70, 1284–1290 (1987).
Article CAS PubMed Google Scholar
Rezvan, A., Ni, C.-W., Alberts-Grill, N. & Jo, H. Animal, in vitro, and ex vivo models of flow-dependent atherosclerosis: role of oxidative stress. Antioxid. Redox Signal. 15, 1433–1448 (2011).
Article CAS PubMed PubMed Central Google Scholar
Colgan, O. C. et al. Regulation of bovine brain microvascular endothelial tight junction assembly and barrier function by laminar shear stress. Am. J. Physiol. Heart Circ. Physiol. 292, H3190–H3197 (2007).
Article CAS PubMed Google Scholar
Orsenigo, F. et al. Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo. Nat. Commun. 3, 1208 (2012).
Caolo, V. et al. Shear stress and VE-cadherin. Arterioscler. Thromb. Vasc. Biol. 38, 2174–2183 (2018).
Article CAS PubMed Google Scholar
Levesque, M. J., Nerem, R. M. & Sprague, E. A. Vascular endothelial cell proliferation in culture and the influence of flow. Biomaterials 11, 702–707 (1990).
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