Particular genomic and virulence traits associated with preterm infant-derived toxigenic Clostridium perfringens strains

Kiu, R. & Hall, L. J. An update on the human and animal enteric pathogen Clostridium perfringens. Emerg. Microbes Infect. 7, 141 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Li, J., Paredes-Sabja, D., Sarker, M. R. & McClane, B. A. Clostridium perfringens sporulation and sporulation-associated toxin production. Microbiol. Spectr. https://doi.org/10.1128/microbiolspec.TBS-0022-2015 (2016).

Rood, J. I. et al. Expansion of the Clostridium perfringens toxin-based typing scheme. Anaerobe 53, 5–10 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ronco, T. et al. Genome analysis of Clostridium perfringens isolates from healthy and necrotic enteritis infected chickens and turkeys. BMC Res. Notes 10, 270 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Lacey, J. A. et al. Whole genome analysis reveals the diversity and evolutionary relationships between necrotic enteritis-causing strains of Clostridium perfringens. BMC Genom. 19, 379 (2018).

Article  Google Scholar 

Kiu, R. et al. Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis. Anim. Microbiome 1, 12 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Mahamat Abdelrahim, A. et al. Large-scale genomic analyses and toxinotyping of Clostridium perfringens implicated in foodborne outbreaks in France. Front. Microbiol. https://doi.org/10.3389/fmicb.2019.00777 (2019).

Kiu, R. et al. Phylogenomic analysis of gastroenteritis-associated Clostridium perfringens in England and Wales over a 7-year period indicates distribution of clonal toxigenic strains in multiple outbreaks and extensive involvement of enterotoxin-encoding (CPE) plasmids. Micro. Genom. https://doi.org/10.1099/mgen.0.000297 (2019).

Camargo, A. et al. Intra-species diversity of Clostridium perfringens: a diverse genetic repertoire reveals its pathogenic potential. Front. Microbiol. 13, 952081 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Neu, J. & Walker, A. W. Necrotizing enterocolitis. N. Engl. J. Med. 364, 255–264 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lim, J. C., Golden, J. M. & Ford, H. R. Pathogenesis of neonatal necrotizing enterocolitis. Pediatr. Surg. Int. 31, 509–518 (2015).

Article  PubMed  Google Scholar 

Lin, P. W. & Stoll, B. J. Necrotising enterocolitis. Lancet 368, 1271–1283 (2006).

Article  PubMed  Google Scholar 

Rees, C. M., Eaton, S. & Pierro, A. National prospective surveillance study of necrotizing enterocolitis in neonatal intensive care units. J. Pediatr. Surg. 45, 1391–1397 (2010).

Article  PubMed  Google Scholar 

Shah, T. A. et al. Hospital and neurodevelopmental outcomes of extremely low-birth-weight infants with necrotizing enterocolitis and spontaneous intestinal perforation. J. Perinatol. 32, 552–558 (2012).

Article  CAS  PubMed  Google Scholar 

Bazacliu, C. & Neu, J. Necrotizing enterocolitis: long term complications. Curr. Pediatr. Rev. 15, 115–124 (2019).

Article  PubMed  Google Scholar 

Coggins, S. A., Wynn, J. L. & Weitkamp, J. H. Infectious causes of necrotizing enterocolitis. Clin. Perinatol. 42, 133–154 (2015).

Article  PubMed  Google Scholar 

Carlisle, E. M. & Morowitz, M. J. The intestinal microbiome and necrotizing enterocolitis. Curr. Opin. Pediatr. 25, 382–387 (2013).

Article  CAS  PubMed  Google Scholar 

Morowitz, M. J., Poroyko, V., Caplan, M., Alverdy, J. & Liu, D. C. Redefining the role of intestinal microbes in the pathogenesis of necrotizing enterocolitis. Pediatrics 125, 777–785 (2010).

Article  PubMed  Google Scholar 

Hanke, C. A. et al. Clostridium perfringens intestinal gas gangrene in a preterm newborn. Eur. J. Pediatr. Surg. 19, 257–259 (2009).

Article  CAS  PubMed  Google Scholar 

Claud, E. C. Neonatal necrotizing enterocolitis: inflammation and intestinal immaturity. Antiinflamm. Antiallergy Agents Med. Chem. 8, 248–259 (2009).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heida, F. H. et al. A necrotizing enterocolitis-associated gut microbiota is present in the meconium: results of a prospective study. Clin. Infect. Dis. 62, 863–870 (2016).

Article  CAS  PubMed  Google Scholar 

Sim, K. et al. Dysbiosis anticipating necrotizing enterocolitis in very premature infants. Clin. Infect. Dis. 60, 389–397 (2015).

Article  CAS  PubMed  Google Scholar 

Butel, M. J. et al. Clostridial pathogenicity in experimental necrotising enterocolitis in gnotobiotic quails and protective role of bifidobacteria. J. Med. Microbiol. 47, 391–399 (1998).

Article  CAS  PubMed  Google Scholar 

Waligora-Dupriet, A. J., Dugay, A., Auzeil, N., Huerre, M. & Butel, M. J. Evidence of clostidial implication in necrotizing enterocolitis through bacterial fermentation in a gnotobiotic quail model. Pediatr. Res. 58, 629–635 (2005).

Article  CAS  PubMed  Google Scholar 

Kosloske, A. M., Ball, W. S. Jr, Umland, E. & Skipper, B. Clostridial necrotizing enterocolitis. J. Pediatr. Surg. 20, 155–159 (1985).

Article  CAS  PubMed  Google Scholar 

Kosloske, A. M., Ulrich, J. A. & Hoffman, H. Fulminant necrotising enterocolitis associated with clostridia. Lancet 312, 1014–1016 (1978).

Article  Google Scholar 

Revitt-Mills, S. A., Watts, T. D., Lyras, D., Adams, V. & Rood, J. I. The ever-expanding tcp conjugation locus of pCW3 from Clostridium perfringens. Plasmid 113, 102516 (2020).

Article  PubMed  Google Scholar 

Watts, T. D. et al. pCP13, a representative of a new family of conjugative toxin plasmids in Clostridium perfringens. Plasmid 102, 37–45 (2019).

Article  CAS  PubMed  Google Scholar 

Lacey, J. A., Johanesen, P. A., Lyras, D. & Moore, R. J. In silico identification of novel toxin homologs and associated mobile genetic elements in Clostridium perfringens. Pathogens 8, 16 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kiu, R. et al. Genomic analysis of Clostridium perfringens BEC/CPILE-positive, toxinotype D and E strains isolated from healthy children. Toxins 11, 543 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng, Y. et al. Phylogenetic and genomic analysis reveals high genomic openness and genetic diversity of Clostridium perfringens. Microb. Genom. https://doi.org/10.1099/mgen.0.000441 (2020).

Kiu, R., Caim, S., Alexander, S., Pachori, P. & Hall, L. J. Probing genomic aspects of the multi-host pathogen Clostridium perfringens reveals significant pangenome diversity, and a diverse array of virulence factors. Front. Microbiol. 8, 2485 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Lakshminarayanan, B. et al. Prevalence and characterization of Clostridium perfringens from the faecal microbiota of elderly Irish subjects. J. Med. Microbiol. 62, 457–466 (2013).

Article  CAS  PubMed  Google Scholar 

Hamza, D., Dorgham, S. M., Elhariri, M., Elhelw, R. & Ismael, E. New insight of apparently healthy animals as a potential reservoir for Clostridium perfringens: a public health implication. J. Vet. Res. 62, 457–462 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Savinov, S. N. & Heuck, A. P. Interaction of cholesterol with perfringolysin O: what have we learned from functional analysis? Toxins 9, 381 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Stevens, D. L. & Bryant, A. E. The role of clostridial toxins in the pathogenesis of gas gangrene. Clin. Infect. Dis. 35, S93–S100 (2002).

Article  CAS  PubMed  Google Scholar 

Verherstraeten, S. et al. The synergistics necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells. Vet. Res. 44, 45 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang, J. et al. Verbascoside protects mice from clostridial gas gangrene by inhibiting the activity of alpha toxin and perfringolysin O. Front. Microbiol. 11, 1504 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, Z., Yan, C., Gong, X. & Wang, J. Severe intravascular hemolysis from Clostridium perfringens septicemia in a neonate with necrotizing enterocolitis in China: a case report. Infect. Drug Resist. 15, 1461–1465 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Suzaki, A. et al. Pathogenic characterization of Clostridium perfringens strains isolated from patients with massive intravascular hemolysis. Front. Microbiol. 12, 713509 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Awad, M. M., Ellemor, D. M., Boyd, R. L., Emmins, J. J. & Rood, J. I. Synergistic effects of alpha-toxin and perfringolysin O in Clostridium perfringens-mediated gas gangrene. Infect. Immun. 69, 7904–7910 (2001).

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