Clinical features and risk factors for interstitial lung disease spreading in low-dose irradiated areas after definitive radiotherapy with or without durvalumab consolidation therapy for patients with non-small cell lung cancer

Antonia A, Villegas D, Daniel D, Vicente S, Murakami R. Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer. N Engl J Med. 2017;377.

Jung HA, Noh JM, Sun JM, Lee SH, Ahn JS, Ahn MJ, et al. Real world data of durvalumab consolidation after chemoradiotherapy in stage III non-small-cell lung cancer. Lung Cancer. 2020;146:23–9.

Article  PubMed  Google Scholar 

Desilets A, Blanc-Durand F, Lau S, Hakozaki T, Kitadai R, Malo J, et al. Durvalumab therapy following chemoradiation compared with a historical cohort treated with chemoradiation alone in patients with stage III non-small cell lung cancer: a real-world multicentre study. Eur J Cancer. 2021;142:83–91.

Article  CAS  PubMed  Google Scholar 

Kasmann L, Dietrich A, Staab-Weijnitz CA, Manapov F, Behr J, Rimner A, et al. Radiation-induced lung toxicity - cellular and molecular mechanisms of pathogenesis, management, and literature review. Radiat Oncol. 2020;15:214.

Article  PubMed  PubMed Central  Google Scholar 

Khunger M, Rakshit S, Pasupuleti V, Hernandez AV, Mazzone P, Stevenson J, et al. Incidence of Pneumonitis with Use of programmed death 1 and programmed death-ligand 1 inhibitors in Non-Small Cell Lung Cancer: a systematic review and Meta-analysis of trials. Chest. 2017;152:271–81.

Article  PubMed  Google Scholar 

Hosoya K, Fujimoto D, Kawachi H, Sato Y, Kogo M, Nagata K, et al. Ineligibility for the PACIFIC trial in unresectable stage III non-small cell lung cancer patients. Cancer Chemother Pharmacol. 2019;84:275–80.

Article  CAS  PubMed  Google Scholar 

Saito G, Oya Y, Taniguchi Y, Kawachi H, Daichi F, Matsumoto H, et al. Real-world survey of pneumonitis and its impact on durvalumab consolidation therapy in patients with non-small cell lung cancer who received chemoradiotherapy after durvalumab approval (HOPE-005/CRIMSON). Lung Cancer. 2021;161:86–93.

Article  CAS  PubMed  Google Scholar 

Kazerooni EA, Martinez FJ, Flint A, Jamadar DA, Gross BH, Spizarny DL, et al. Thin-section CT obtained at 10-mm increments versus limited three-level thin-section CT for idiopathic pulmonary fibrosis: correlation with pathologic scoring. AJR Am J Roentgenol. 1997;169:977–83.

Article  CAS  PubMed  Google Scholar 

Satoh K, Kobayashi T, Misao T, Hitani Y, Yamamoto Y, Nishiyama Y, et al. CT assessment of subtypes of pulmonary emphysema in smokers. Chest. 2001;120:725–9.

Article  CAS  PubMed  Google Scholar 

Graham MV, Purdy JA, Emami B, Harms W, Bosch W, Lockett MA, et al. Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys. 1999;45:323–9.

Article  CAS  PubMed  Google Scholar 

Tsujino K, Hirota S, Endo M, Obayashi K, Kotani Y, Satouchi M, et al. Predictive value of dose-volume histogram parameters for predicting radiation pneumonitis after concurrent chemoradiation for lung cancer. Int J Radiat Oncol Biol Phys. 2003;55:110–5.

Article  PubMed  Google Scholar 

Palma DA, Senan S, Tsujino K, Barriger RB, Rengan R, Moreno M, et al. Predicting radiation pneumonitis after chemoradiation therapy for lung cancer: an international individual patient data meta-analysis. Int J Radiat Oncol Biol Phys. 2013;85:444–50.

Article  PubMed  Google Scholar 

Faivre-Finn C, Spigel DR, Senan S, Langer C, Perez BA, Özgüroğlu M, et al. Impact of prior chemoradiotherapy-related variables on outcomes with durvalumab in unresectable stage III NSCLC (PACIFIC). Lung Cancer. 2021;151:30–8.

Article  CAS  PubMed  Google Scholar 

Horinouchi H, Atagi S, Oizumi S, Ohashi K, Kato T, Kozuki T, et al. Real-world outcomes of chemoradiotherapy for unresectable stage III non-small cell lung cancer: the SOLUTION study. Cancer Med. 2020;9:6597–608.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arroyo-Hernandez M, Maldonado F, Lozano-Ruiz F, Munoz-Montano W, Nunez-Baez M, Arrieta O. Radiation-induced lung injury: current evidence. BMC Pulm Med. 2021;21:9.

Article  PubMed  PubMed Central  Google Scholar 

Hernando ML, Marks LB, Bentel GC, Zhou SM, Hollis D, Das SK, et al. Radiation-induced pulmonary toxicity: a dose-volume histogram analysis in 201 patients with lung cancer. Int J Radiat Oncol Biol Phys. 2001;51:650–9.

Article  CAS  PubMed  Google Scholar 

Fay M, Tan A, Fisher R, Mac Manus M, Wirth A, Ball D. Dose-volume histogram analysis as predictor of radiation pneumonitis in primary lung cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys. 2005;61:1355–63.

Article  PubMed  Google Scholar 

Yom SS, Liao Z, Liu HH, Tucker SL, Hu CS, Wei X, et al. Initial evaluation of treatment-related pneumonitis in advanced-stage non-small-cell lung cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2007;68:94–102.

Article  CAS  PubMed  Google Scholar 

Wirsdörfer F, Cappuccini F, Niazman M, de Leve S, Westendorf AM, Lüdemann L, et al. Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4 + FoxP3 + regulatory T cells. Radiat Oncol. 2014;9:98.

Article  PubMed  PubMed Central  Google Scholar 

Guo T, Zou L, Ni J, Zhou Y, Ye L, Yang X, et al. Regulatory T cells: an emerging player in Radiation-Induced Lung Injury. Front Immunol. 2020;11:1769.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thakur P, DeBo R, Dugan GO, Bourland JD, Michalson KT, Olson JD, et al. Clinicopathologic and transcriptomic analysis of Radiation-Induced Lung Injury in Nonhuman Primates. Int J Radiat Oncol Biol Phys. 2021;111:249–59.

Article  PubMed  PubMed Central  Google Scholar 

Kong M, Lim YJ, Kim Y, Chung MJ, Min S, Shin DO, et al. Diabetes mellitus is a predictive factor for radiation pneumonitis after thoracic radiotherapy in patients with lung cancer. Cancer Manag Res. 2019;11:7103–10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ergen SA, Dincbas FO, Yücel B, Altınok P, Akyurek S, Korkmaz Kıraklı E, et al. Risk factors of radiation pneumonitis in patients with NSCLC treated with concomitant chemoradiotherapy–are we underestimating diabetes?--Turkish oncology group (TOG)/Lung cancer study group. Clin Respir J. 2020;14:871–79.

CAS  PubMed  Google Scholar 

Alexandraki KI, Piperi C, Ziakas PD, Apostolopoulos NV, Makrilakis K, Syriou V, et al. Cytokine secretion in long-standing diabetes mellitus type 1 and 2: associations with low-grade systemic inflammation. J Clin Immunol. 2008;28:314–21.

Article  CAS  PubMed  Google Scholar 

Omori K, Ohira T, Uchida Y, Ayilavarapu S, Batista EL Jr, Yagi M, et al. Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase. J Leukoc Biol. 2008;84:292–301.

Article  CAS  PubMed  PubMed Central  Google Scholar 

El-Benna J, Hurtado-Nedelec M, Marzaioli V, Marie JC, Gougerot-Pocidalo MA, Dang PM. Priming of the neutrophil respiratory burst: role in host defense and inflammation. Immunol Rev. 2016;273:180–93.

Article  CAS  PubMed  Google Scholar 

Carestia A, Frechtel G, Cerrone G, Linari MA, Gonzalez CD, Casais P, et al. NETosis before and after Hyperglycemic Control in type 2 diabetes Mellitus Patients. PLoS ONE. 2016;11:e0168647.

Article  PubMed  PubMed Central  Google Scholar 

Chun SG, Hu C, Choy H, Komaki RU, Timmerman RD, Schild SE, et al. Impact of intensity-modulated Radiation Therapy technique for locally Advanced Non-Small-Cell Lung Cancer: a secondary analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial. J Clin Oncol. 2017;35:56–62.

Article  PubMed  Google Scholar 

Hu Y, Li J, Su X. Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: case report and review. Oncol Lett. 2013;5:714–16.

Article  PubMed  Google Scholar 

Hassanzadeh C, Sita T, Savoor R, Samson PP, Bradley J, Gentile M, et al. Implications of pneumonitis after chemoradiation and durvalumab for locally advanced non-small cell lung cancer. J Thorac Dis. 2020;12:6690–700.

Article  PubMed  PubMed Central  Google Scholar 

Tsukita Y, Yamamoto T, Mayahara H, Hata A, Takeda Y, Nakayama H, et al. Intensity-modulated radiation therapy with concurrent chemotherapy followed by durvalumab for stage III non-small cell lung cancer: a multi-center retrospective study. Radiother Oncol. 2021;160:266–72.

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif