Jeppesen D, Zhang Q, Franklin J, Coffey R. Extracellular vesicles and nanoparticles: emerging complexities. Trends Cell Biol. 2023. https://doi.org/10.1016/j.tcb.2023.01.002.
Van der Heyden A, Chanthavong P, Angles-Cano E, Bonnet H, Dejeu J, Cras A, et al. Grafted dinuclear zinc complexes for selective recognition of phosphatidylserine: application to the capture of extracellular membrane microvesicles. J Inorg Biochem. 2023;239:112065.
Han Q-F, Li W-J, Hu K-S, Gao J, Zhai W-L, Yang J-H, et al. Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer. Mol Cancer. 2022;21:207.
Article PubMed PubMed Central Google Scholar
Zhou M, Li Y-J, Tang Y-C, Hao X-Y, Xu W-J, Xiang D-X, et al. Apoptotic bodies for advanced drug delivery and therapy. J Controlled Release. 2022;351:394–406.
Zhang H, Freitas D, Kim HS, Fabijanic K, Li Z, Chen H, et al. Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation. Nat Cell Biol. 2018;20:332–43.
Article CAS PubMed PubMed Central Google Scholar
Anand S, Samuel M, Mathivanan S, Exomeres. A New Member of Extracellular Vesicles Family. Subcell Biochem. 2021;97:89–97.
Article CAS PubMed Google Scholar
Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, et al. Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets. Nat Cell Biol. 2021;23:1240–54.
Article CAS PubMed PubMed Central Google Scholar
Li X, Corbett AL, Taatizadeh E, Tasnim N, Little JP, Garnis C, et al. Challenges and opportunities in exosome research-perspectives from biology, engineering, and cancer therapy. APL Bioeng. 2019;3:011503.
Article PubMed PubMed Central Google Scholar
Cocucci E, Meldolesi J. Ectosomes and exosomes: shedding the confusion between extracellular vesicles. Trends Cell Biol. 2015;25:364–72.
Article CAS PubMed Google Scholar
Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018;7:1535750.
Article PubMed PubMed Central Google Scholar
Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428–45e18.
Article CAS PubMed PubMed Central Google Scholar
Kalluri R, LeBleu VS. The biology, function, and biomedical applications of exosomes. Science. 2020;367:eaau6977.
Article CAS PubMed PubMed Central Google Scholar
Mulcahy LA, Pink RC, Carter DRF. Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles. 2014;3:24641.
Isaac R, Reis F, Ying W, Olefsky J. Exosomes as mediators of intercellular crosstalk in metabolism. Cell Metab. 2021;33:1744–62.
Article CAS PubMed PubMed Central Google Scholar
Tkach M, Théry C. Communication by Extracellular vesicles: where we are and where we need to go. Cell. 2016;164:1226–32.
Article CAS PubMed Google Scholar
Pluchino S, Smith J. Explicating Exosomes: reclassifying the rising stars of Intercellular Communication. Cell. 2019;177:225–7.
Article CAS PubMed Google Scholar
Plikus M, Wang X, Sinha S, Forte E, Thompson S, Herzog E, et al. Fibroblasts: Origins, definitions, and functions in health and disease. Cell. 2021;184:3852–72.
Article CAS PubMed PubMed Central Google Scholar
Moretti L, Stalfort J, Barker TH, Abebayehu D. The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation. J Biol Chem. 2022;298:101530.
Article CAS PubMed Google Scholar
Xue D, Tabib T, Morse C, Yang Y, Domsic RT, Khanna D, et al. Expansion of Fcγ receptor IIIa-Positive macrophages, ficolin 1-Positive monocyte-derived dendritic cells, and Plasmacytoid dendritic cells Associated with severe skin disease in systemic sclerosis. Arthritis Rheumatol. 2022;74:329–41.
Article CAS PubMed PubMed Central Google Scholar
Zhao M, Wang L, Wang M, Zhou S, Lu Y, Cui H, et al. Targeting fibrosis, mechanisms and cilinical trials. Signal Transduct Target Ther. 2022;7:206.
Article PubMed PubMed Central Google Scholar
Rockey DC, Bell PD, Hill JA. Fibrosis–a common pathway to organ injury and failure. N Engl J Med. 2015;372:1138–49.
Article CAS PubMed Google Scholar
Lo Cicero A, Stahl PD, Raposo G. Extracellular vesicles shuffling intercellular messages: for good or for bad. Curr Opin Cell Biol. 2015;35:69–77.
Article CAS PubMed Google Scholar
Krenkel O, Hundertmark J, Ritz TP, Weiskirchen R, Tacke F. Single cell RNA sequencing identifies subsets of hepatic stellate cells and Myofibroblasts in Liver Fibrosis. Cells. 2019;8:503.
Article CAS PubMed PubMed Central Google Scholar
Habermann AC, Gutierrez AJ, Bui LT, Yahn SL, Winters NI, Calvi CL, et al. Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis. Sci Adv. 2020;6:eaba1972.
Article CAS PubMed PubMed Central Google Scholar
Rao M, Wang X, Guo G, Wang L, Chen S, Yin P, et al. Resolving the intertwining of inflammation and fibrosis in human heart failure at single-cell level. Basic Res Cardiol. 2021;116:55.
Wang FD, Zhou J, Chen EQ. Molecular mechanisms and potential new therapeutic drugs for liver fibrosis. Front Pharmacol. 2022;13:787748.
Article CAS PubMed PubMed Central Google Scholar
Gu H, Yang K, Shen Z, Jia K, Liu P, Pan M, et al. ER stress-induced adipocytes secrete-aldo-keto reductase 1B7-containing exosomes that cause nonalcoholic steatohepatitis in mice. Free Radical Biol Med. 2021;163:220–33.
Hirsova P, Ibrahim SH, Krishnan A, Verma VK, Bronk SF, Werneburg NW, et al. Lipid-Induced Signaling causes release of inflammatory extracellular vesicles from hepatocytes. Gastroenterology. 2016;150:956–67.
Article CAS PubMed Google Scholar
Seo W, Eun HS, Kim SY, Yi HS, Lee YS, Park SH, et al. Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosis. Hepatology. 2016;64:616–31.
Article CAS PubMed Google Scholar
Eguchi A, Yan R, Pan SQ, Wu R, Kim J, Chen Y, et al. Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice. J Mol Med (Berl). 2020;98:1021–34.
Article CAS PubMed Google Scholar
Liu X, Tan S, Liu H, Jiang J, Wang X, Li L, et al. Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis. Hepatology. 2022. https://doi.org/10.1002/hep.32662.
Gao H, Jin Z, Bandyopadhyay G, Wang G, Zhang D, Rocha K, et al. Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis. Cell Metab. 2022;34:1201–13e5.
Article CAS PubMed Google Scholar
Zhang X, Zeng Y, Zhao L, Xu Q, Miao D, Yu F. Targeting Hepatic Stellate Cell Death to Reverse Hepatic Fibrosis. Current drug targets. 2023. https://doi.org/10.2174/1389450124666230330135834.
Chen L, Yao X, Yao H, Ji Q, Ding G, Liu X. Exosomal mir-103-3p from LPS-activated THP-1 macrophage contributes to the activation of hepatic stellate cells. Faseb j. 2020;34:5178–92.
Article CAS PubMed Google Scholar
Gao J, Wei B, de Assuncao TM, Liu Z, Hu X, Ibrahim S, et al. Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis. J Hepatol. 2020;73:1144–54.
Article CAS PubMed PubMed Central Google Scholar
Kostallari E, Hirsova P, Prasnicka A, Verma VK, Yaqoob U, Wongjarupong N, et al. Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2. Hepatology. 2018;68:333–48.
留言 (0)