Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications

Dr. Assaf Zinger is a researcher and educator in the field of nanomedicine and engineering. He currently serves as an Assistant Professor at the Technion - Israel Institute of Technology, where he has been a faculty member in the Department of Chemical Engineering since 2021. Dr. Zinger also serves as Adjunct Assistant Professor at Houston Methodist Academic Institute in the Cardiovascular Sciences and Neurosurgery Departments, TX, USA. Dr. Zinger earned his B.Sc. in biomedical engineering from the Technion and his Ph.D. in chemical engineering from the same institute. His doctoral research, mentored by Prof. Avi Schroeder, focused on developing bioactive nanoparticles. Recognizing the limitations of conventional drug carriers and the need for a more translational approach in this field, Dr. Zinger pursued further training as a Postdoctoral researcher at the Houston Methodist Academic Institute & Houston Methodist Hospital, under the mentorship of renowned scientists and physicians such as Profs. Ennio Tasciotti and Francesca Taraballi, as well as other esteemed professionals. Since joining Technion, Dr. Zinger has established a strong and diverse research group focused on developing and characterizing biomimetic nanoparticles for various applications. His research covers intradisciplinary fields, starting from biochemical engineering, where he and his team are engaged in the design, fabrication, and characterization of biomimetic nanoparticles, to biomedical engineering, where they test these nanoparticles for their efficacy against a range of ailments such as neurodegenerative diseases, brain injuries, and multiple cancers using advanced imaging instruments. He has authored and co-authored 24 peer-reviewed publications in top-tier journals, and his research has been supported by grants from international and Israeli funding agencies. In addition to his research activities, Dr. Zinger is also an accomplished educator and mentor. He has developed and taught several undergraduate and graduate courses on topics including bioinspired engineering and chemical engineering. He has also co-established the "Tzameret Program", in which Technion students meet with high school students to discuss research and academic studies, and the chemical engineering department undergraduate excellence program “Lavie”. Dr. Zinger is a member of the international controlled release society annual meeting planning committee and also chaired the prestigious Cancer Nano Medicine- Gordon Research Seminar and the Young Israeli Controlled Society conference. In addition, Dr. Zinger is a guest associate editor for Bioengineering & Translational Medicine (BioTM) and editorial board member for the Journal of Controlled Release (JCR). He has been recognized for his contributions with more than 15 national and international awards and honors. These include the Alon Scholarship for outstanding young scientists, the most prestigious scholarship from the Israeli Council for Higher Education; the international Umbrella Award, focusing on Life Science and Engineering; the Norman Seiden Fellowship in Nanotechnology and Optoelectronics, Career Advancement Chair. Last year, Dr. Zinger was also chosen as a member of the Global Young Academy and will participate in the upcoming Lindau Noble Laureate Meeting as a young scientist. An overview of Dr. Zinger’s lab scientific work can be found at- www.TheZingerLab.com

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