Mollan SP, Aguiar M, Evison F, Frew E, Sinclair AJ. The expanding burden of idiopathic intracranial hypertension. Eye. 2019;33:478–85.

Article  PubMed  Google Scholar 

Mollan SP, Grech O, Alimajstorovic Z, Wakerley BR, Sinclair AJ. New horizons for idiopathic intracranial hypertension: advances and challenges. Br Med Bull. 2020;136:118–26.

Article  CAS  PubMed  Google Scholar 

Mollan SP, Mytton J, Tsermoulas G, Sinclair AJ. Idiopathic intracranial hypertension: evaluation of admissions and emergency readmissions through the hospital episode statistic dataset between 2002–2020. Life. 2021;11:417.

Article  PubMed  PubMed Central  Google Scholar 

Mollan SP, Grech O, Sinclair AJ. Headache attributed to idiopathic intracranial hypertension and persistent post-idiopathic intracranial hypertension headache: A narrative review. Headache. 2021;61:808–16.

Article  PubMed  Google Scholar 

Rotterdam ESHRE ASRM-Sponsored Pcos Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81:19–25.

Article  Google Scholar 

Zawadski J, Dunaif A Diagnostic criteria for polycystic ovary syndrome In: Givens JHF MG.(ed). The Polycystic Ovary Syndrome: Cambridge, MA: Blackwell Scientific, 1992.

O’Reilly MW, Westgate CS, Hornby C, Botfield H, Taylor AE, Markey K, et al. A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics. JCI Insight. 2019;4:e125348.

PubMed  PubMed Central  Google Scholar 

O’Reilly MW, Kempegowda P, Walsh M, Taylor AE, Manolopoulos KN, Allwood JW, et al. AKR1C3-mediated adipose androgen generation drives lipotoxicity in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2017;102:3327–39.

Article  PubMed  PubMed Central  Google Scholar 

Hornby C, Mollan SP, Botfield H, O’Reilly MW, Sinclair AJ. Metabolic concepts in idiopathic intracranial hypertension and their potential for therapeutic intervention. J Neuroophthalmol. 2018;38:522–30.

Article  PubMed  PubMed Central  Google Scholar 

Westgate CSJ, Botfield HF, Alimajstorovic Z, Yiangou A, Walsh M, Smith G, et al. Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension. JCI Insight. 2021;6:e145346.

Article  PubMed  PubMed Central  Google Scholar 

Hornby C, Botfield H, O’Reilly MW, Westgate C, Mitchell J, Mollan SP, et al. Evaluating the fat distribution in idiopathic intracranial hypertension Using dual-energy X-ray absorptiometry scanning. Neuroophthalmology. 2018;42:99–104.

Article  PubMed  Google Scholar 

Adderley NJ, Subramanian A, Nirantharakumar K, Yiangou A, Gokhale KM, Mollan SP, et al. Association between idiopathic intracranial hypertension and risk of cardiovascular diseases in women in the United Kingdom. JAMA Neurol. 2019;76:1088–98.

Article  PubMed  PubMed Central  Google Scholar 

Wild RA, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, et al. Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. J Clin Endocrinol Metab. 2010;95:2038–49.

Article  CAS  PubMed  Google Scholar 

Grech O, Clouter A, Mitchell JL, Alimajstorovic Z, Ottridge RS, Yiangou A, et al. Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure. Brain Commun. 2021;3:fcab202.

Article  PubMed  PubMed Central  Google Scholar 

Sukhapure M, Eggleston K, Douglas K, Fenton A, Frampton C, Porter RJ. Free testosterone is related to aspects of cognitive function in women with and without polycystic ovary syndrome. Arch Women’s Ment Health. 2022;25:87–94.

Article  Google Scholar 

Barnard L, Balen AH, Ferriday D, Tiplady B, Dye L. Cognitive functioning in polycystic ovary syndrome. Psychoneuroendocrinology. 2007;32:906–14.

Article  CAS  PubMed  Google Scholar 

Yiangou A, Mitchell JL, Nicholls M, Chong YJ, Vijay V, Wakerley BR, et al. Obstructive sleep apnoea in women with idiopathic intracranial hypertension: a sub-study of the idiopathic intracranial hypertension weight randomised controlled trial (IIH: WT). J Neurol. 2022;269:1945–56.

Article  PubMed  Google Scholar 

Kumarendran B, Sumilo D, O’Reilly MW, Toulis KA, Gokhale KM, Wijeyaratne CN, et al. Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study. Eur J Endocrinol. 2019;180:265–72.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bahri Khomami M, Joham AE, Boyle JA, Piltonen T, Silagy M, Arora C, et al. Increased maternal pregnancy complications in polycystic ovary syndrome appear to be independent of obesity—A systematic review, meta‐analysis, and meta‐regression. Obes Rev. 2019;20:659–74.

Article  PubMed  Google Scholar 

Joham AE, Teede HJ, Ranasinha S, Zoungas S, Boyle J. Prevalence of infertility and use of fertility treatment in women with polycystic ovary syndrome: data from a large community-based cohort study. J Women’s Health (Larchmt). 2015;24:299–307.

Article  Google Scholar 

Moran L, Teede H. Metabolic features of the reproductive phenotypes of polycystic ovary syndrome. Hum Reprod Update. 2009;15:477–88.

Article  CAS  PubMed  Google Scholar 

Thaller M, Mytton J, Wakerley BR, Mollan SP, Sinclair AJ. Idiopathic intracranial hypertension: evaluation of births and fertility through the hospital episode statistic dataset. BJOG. 2022;129:2019–27.

Article  PubMed  PubMed Central  Google Scholar 

Avisar I, Gaton DD, Dania H, Stiebel-Kalish H. The prevalence of polycystic ovary syndrome in women with idiopathic intracranial hypertension. Sci (Cairo). 2012;2012:708042.

Google Scholar 

Glueck CJ, Aregawi D, Goldenberg N, Golnik KC, Sieve L, Wang P. Idiopathic intracranial hypertension, polycystic-ovary syndrome, and thrombophilia. J Lab Clin Med. 2005;145:72–82.

Article  PubMed  Google Scholar 

Glueck CJ, Iyengar S, Goldenberg N, Smith LS, Wang P. Idiopathic intracranial hypertension: associations with coagulation disorders and polycystic-ovary syndrome. J Lab Clin Med. 2003;142:35–45.

Article  CAS  PubMed  Google Scholar 

Friedman DI, Liu GT, Digre KB. Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children. Neurology. 2013;81:1159–65.

Article  PubMed  Google Scholar 

Aojula A, Mollan SP, Horsburgh J, Yiangou A, Markey KA, Mitchell JL, et al. Segmentation error in spectral domain optical coherence tomography measures of the retinal nerve fibre layer thickness in idiopathic intracranial hypertension. BMC Ophthalmol. 2018;17:257.

Article  PubMed  PubMed Central  Google Scholar 

Kosinski M, Bayliss MS, Bjorner JB, Ware JE, Garber WH, Batenhorst A, et al. A six-item short-form survey for measuring headache impact: The HIT-6™. Qual Life Res. 2003;12:963–74.

Article  CAS  PubMed  Google Scholar 

Headache Classification Committe of the International Headache Society. The international classification of headache disorders, 3rd edition (beta version). Cephalalgia. 2013;33:629–808.

Article  Google Scholar 

Bates DM, Bolker M, Walker B, Fitting S. Linear mixed-effects models using lme4. J Stat Softw. 2015;67:1–48.

Article  Google Scholar 

Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010;8:41.

Article  CAS  PubMed  PubMed Central  Google Scholar 

March WA, Moore VM, Willson KJ, Phillips DI, Norman RJ, Davies MJ. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum Reprod. 2010;25:544–51.

Article  PubMed  Google Scholar 

Wilkes S, Chinn DJ, Murdoch A, Rubin G. Epidemiology and management of infertility: a population-based study in UK primary care. Fam Pract. 2009;26:269–74.

Article  PubMed  Google Scholar 

Thaller M, Wakerley BR, Abbott S, Tahrani AA, Mollan SP, Sinclair AJ. Managing idiopathic intracranial hypertension in pregnancy: practical advice. Pract Neurol. 2022;22:295–300.

Article  PubMed  PubMed Central  Google Scholar 

Thaller M, Homer V, Hyder Y, Yiangou A, Liczkowski A, Fong A, et al. The idiopathic intracranial hypertension prospective cohort study: Evaluation of prognostic factors and outcomes. J Neurol. 2022;270:851–63.

Article  PubMed  PubMed Central  Google Scholar 

Sinclair AJ, Burdon MA, Nightingale PG, Ball AK, Good P, Matthews TD, et al. Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ. 2010;341:c2701.

Article  PubMed  PubMed Central  Google Scholar 

Mollan SP, Davies B, Silver NC, Shaw S, Mallucci CL, Wakerley BR, et al. Idiopathic intracranial hypertension: consensus guidelines on management. J Neurol Neurosurg Psychiatry. 2018;89:1088–100.

Article  PubMed  Google Scholar 

Thaller M, Tsermoulas G, Sun R, Mollan SP, Sinclair AJ. Negative impact of COVID-19 lockdown on papilloedema and idiopathic intracranial hypertension. J Neurol Neurosurg Psychiatry. 2021;92:795–97.

Article  PubMed  Google Scholar 

Ball AK, Howman A, Wheatley K, Burdon MA, Matthews T, Jacks AS, et al. A randomised controlled trial of treatment for idiopathic intracranial hypertension. J Neurol. 2011;258:874–81.

Article  CAS  PubMed