Physiological and pathological consequences of exosomes at the blood–brain-barrier interface

Heidarzadeh M, Gürsoy-Özdemir Y, Kaya M, Eslami Abriz A, Zarebkohan A, Rahbarghazi R, Sokullu E. Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls. Cell Biosci. 2021;11(1):1–28.

Article  Google Scholar 

Obermeier B, Daneman R, Ransohoff RM. Development, maintenance and disruption of the blood-brain barrier. Nat Med. 2013;19(12):1584–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Linville RM, DeStefano JG, Sklar MB, Xu Z, Farrell AM, Bogorad MI, Chu C, Walczak P, Cheng L, Mahairaki V. Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior. Biomaterials. 2019;190:24–37.

Article  PubMed  Google Scholar 

Haruwaka K, Ikegami A, Tachibana Y, Ohno N, Konishi H, Hashimoto A, Matsumoto M, Kato D, Ono R, Kiyama H. Dual microglia effects on blood brain barrier permeability induced by systemic inflammation. Nat Commun. 2019;10(1):1–17.

Article  Google Scholar 

Oztop-Cakmak O, Solaroglu I, Gursoy-Ozdemir Y. The role of pericytes in neurovascular unit: emphasis on stroke. Curr Drug Targets. 2017;18(12):1386–91.

Article  CAS  PubMed  Google Scholar 

Li YN, Pan R, Qin XJ, Yang WL, Qi Z, Liu W, Liu KJ. Ischemic neurons activate astrocytes to disrupt endothelial barrier via increasing VEGF expression. J Neurochem. 2014;129(1):120–9.

Article  CAS  PubMed  Google Scholar 

Mäger I, Meyer AH, Li J, Lenter M, Hildebrandt T, Leparc G, Wood MJ. Targeting blood-brain-barrier transcytosis–perspectives for drug delivery. Neuropharmacology. 2017;120:4–7.

Article  PubMed  Google Scholar 

Hajal C, Le Roi B, Kamm RD, Maoz BM. Biology and Models of the Blood–brain Barrier. Annu Rev Biomed Eng. 2021;23:359–84.

Article  CAS  PubMed  Google Scholar 

Garrido-Urbani S, Bradfield P, Imhof B. Tight junction dynamics: the role of junctional adhesion molecules (JAMs). Cell Tissue Res. 2014;355(3):701–15.

Article  CAS  PubMed  Google Scholar 

Berndt P, Winkler L, Cording J, Breitkreuz-Korff O, Rex A, Dithmer S, Rausch V, Blasig R, Richter M, Sporbert A. Tight junction proteins at the blood–brain barrier: far more than claudin-5. Cell Mol Life Sci. 2019;76(10):1987–2002.

Article  CAS  PubMed  Google Scholar 

Walter FR, Harazin A, Tóth AE, Veszelka S, Santa-Maria AR, Barna L, Kincses A, Biczó G, Balla Z, Kui B. Blood–brain barrier dysfunction in L-ornithine induced acute pancreatitis in rats and the direct effect of L-ornithine on cultured brain endothelial cells. Fluids Barriers CNS. 2022;19(1):1–20.

Article  Google Scholar 

Geranmayeh MH, Rahbarghazi R, Farhoudi M. Targeting pericytes for neurovascular regeneration. Cell Commun Signal. 2019;17(1):1–13.

Article  Google Scholar 

Winek K, Soreq H, Meisel A. Regulators of cholinergic signaling in disorders of the central nervous system. J Neurochem. 2021;158(6):1425–38.

Article  CAS  PubMed Central  Google Scholar 

Ho MS. Microglia in Parkinson’s Disease. In: Verkhratsky A, Ho MS, Zorec R, Parpura V (eds) Neuroglia in Neurodegenerative Diseases. Singapore: Springer Singapore; 2019. pp 335–53. https://doi.org/10.1007/978-981-13-9913-8_13.

Fan Y-Y, Huo J. A1/A2 astrocytes in central nervous system injuries and diseases: Angels or devils? Neurochem Int. 2021;148: 105080.

Article  CAS  PubMed  Google Scholar 

Vinters HV, Kleinschmidt-DeMasters B. General pathology of the central nervous system. In: Greenfield's Neuropathology-Two Volume Set. CRC Press. 2018; pp 25–82.

Arvanitis CD, Ferraro GB, Jain RK. The blood–brain barrier and blood–tumour barrier in brain tumours and metastases. Nat Rev Cancer. 2020;20(1):26–41.

Article  CAS  PubMed  Google Scholar 

Walter FR, Harazin A, Tóth AE, Veszelka S, Santa-Maria AR, Barna L, Kincses A, Biczó G, Balla Z, Kui B, Maléth J, Cervenak L, Tubak V, Kittel Á, Rakonczay Z, Deli MA. Blood–brain barrier dysfunction in l-ornithine induced acute pancreatitis in rats and the direct effect of l-ornithine on cultured brain endothelial cells. Fluids Barriers of the CNS. 2022;19(1):16. https://doi.org/10.1186/s12987-022-00308-0.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Van Niel G, d’Angelo G, Raposo G. Shedding light on the cell biology of extracellular vesicles. Nat Rev Mol Cell Biol. 2018;19(4):213.

Article  PubMed  Google Scholar 

Seyedaghamiri F, Salimi L, Ghaznavi D, Sokullu E, Rahbarghazi R. Exosomes-based therapy of stroke, an emerging approach toward recovery. Cell Commun Signal. 2022;20(1):110. https://doi.org/10.1186/s12964-022-00919-y.

Article  PubMed  PubMed Central  Google Scholar 

Rajabi H, Konyalilar N, Erkan S, Mortazavi D, Korkunc SK, Kayalar O, Bayram H, Rahbarghazi R. Emerging role of exosomes in the pathology of chronic obstructive pulmonary diseases; destructive and therapeutic properties. Stem Cell Res Ther. 2022;13(1):144. https://doi.org/10.1186/s13287-022-02820-4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Seyedaghamiri F, Salimi L, Ghaznavi D, Sokullu E, Rahbarghazi R. Exosomes-based therapy of stroke, an emerging approach toward recovery. Cell Commun Signal. 2022;20(1):1–18.

Article  Google Scholar 

Rezabakhsh A, Cheraghi O, Nourazarian A, Hassanpour M, Kazemi M, Ghaderi S, Faraji E, Rahbarghazi R, Avci ÇB, Bagca BG. Type 2 diabetes inhibited human mesenchymal stem cells angiogenic response by over-activity of the autophagic pathway. J Cell Biochem. 2017;118(6):1518–30.

Article  CAS  PubMed  Google Scholar 

Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018;7(1):1535750.

Article  PubMed  PubMed Central  Google Scholar 

Donoso-Quezada J, Ayala-Mar S, González-Valdez J. The role of lipids in exosome biology and intercellular communication: Function, analytics and applications. Traffic. 2021;22(7):204–20. https://doi.org/10.1111/tra.12803

Heidarzadeh M, Sokullu E, Saghati S, Karimipour M, Rahbarghazi R. Insights into the critical role of exosomes in the brain; from neuronal activity to therapeutic effects. Mol Neurobiol. 2022;1–13.

Bagi HM, Ahmadi S, Tarighat F, Rahbarghazi R, Soleimanpour H. Interplay between exosomes and autophagy machinery in pain management: state of the art. Neurobiol Pain. 2022;12:100095.

Article  Google Scholar 

Mostafazadeh M, Kahroba H, Haiaty S, TazeKand AP, Samadi N, Rahbarghazi R, Nouri M. In vitro exosomal transfer of Nrf2 led to the oxaliplatin resistance in human colorectal cancer LS174T cells. Cell Biochem Funct. 2022;40(4):391–402.

Article  CAS  PubMed  Google Scholar 

Amini H, Rezabakhsh A, Heidarzadeh M, Hassanpour M, Hashemzadeh S, Ghaderi S, Sokullu E, Rahbarghazi R, Reiter RJ. An examination of the putative role of melatonin in exosome biogenesis. Front Cell Dev Biol. 2021;9:686551.

Article  PubMed  PubMed Central  Google Scholar 

Jafari R, Rahbarghazi R, Ahmadi M, Hassanpour M, Rezaie J. Hypoxic exosomes orchestrate tumorigenesis: molecular mechanisms and therapeutic implications. J Transl Med. 2020;18(1):1–14.

Article  Google Scholar 

Salimi L, Akbari A, Jabbari N, Mojarad B, Vahhabi A, Szafert S, Kalashani SA, Soraya H, Nawaz M, Rezaie J. Synergies in exosomes and autophagy pathways for cellular homeostasis and metastasis of tumor cells. Cell Biosci. 2020;10:1–18.

Article  Google Scholar 

Xunian Z, Kalluri R. Biology and therapeutic potential of mesenchymal stem cell-derived exosomes. Cancer Sci. 2020;111(9):3100.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Buratta S, Tancini B, Sagini K, Delo F, Chiaradia E, Urbanelli L, Emiliani C. Lysosomal exocytosis, exosome release and secretory autophagy: The autophagic-and endo-lysosomal systems go extracellular. Int J Mol Sci. 2020;21(7):2576.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Larios J, Mercier V, Roux A, Gruenberg J. ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes. J Cell Biol. 2020;219(3):e201904113.

Article  PubMed  PubMed Central  Google Scholar 

Agarwal S, Agarwal V, Agarwal M, Singh M. Exosomes: structure, biogenesis, types and application in diagnosis and gene and drug delivery. Curr Gene Ther. 2020;20(3):195–206. https://doi.org/10.2174/1566523220999200731011702.

Rahbarghazi R, Jabbari N, Sani NA, Asghari R, Salimi L, Kalashani SA, Feghhi M, Etemadi T, Akbariazar E, Mahmoudi M. Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications. Cell Commun Signal. 2019;17(1):1–17.

Article  Google Scholar 

Peng C, Huang Y, Zheng J. Renal clearable nanocarriers: Overcoming the physiological barriers for precise drug delivery and clearance. J Control Release. 2020;322:64–80. https://doi.org/10.1016/j.jconrel.2020.03.020.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stalder D, Gershlick DC Direct trafficking pathways from the Golgi apparatus to the plasma membrane. In: Seminars in cell & developmental biology, 2020. Elsevier,

Jia G. Sowers JR (2020) Targeting endothelial exosomes for the prevention of cardiovascular disease. Biochim Biophys Acta Mol Basis Dis. 2020;1866(8):165833.

Article  CAS  PubMed  Google Scholar 

Furtado D, Björnmalm M, Ayton S, Bush AI, Kempe K, Caruso F. Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases. Adv Mater. 2018;30(46):1801362.

Article  Google Scholar 

Schwarzenbach H, Gahan PB. MicroRNA shuttle from cell-to-cell by exosomes and its impact in cancer. Non-coding RNA. 2019;5(1):28.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Asil SM, Ahlawat J, Barroso GG, Narayan M. Nanomaterial based drug delivery systems for the treatment of neurodegenerative diseases. Biomater Sci. 2020;8(15):4109–28.

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