Salivary Gland Secretory Carcinoma: Clinicopathologic and Genetic Characteristics of 215 Cases and Proposal for a Grading System

*Department of Pathology, Charles University, Faculty of Medicine in Plzen

†Bioptic Laboratory Ltd Plzen

∥Molecular Genetic Laboratory, Bioptic Laboratory Ltd, Plzen

#The Fingerland Department of Pathology, Charles University, Faculty of Medicine and University Hospital Hradec Kralove, Hradec Kralove

***Department of Otorhinolaryngology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic

‡Head and Neck Pathology Consultations, Woodland Hills, CA

§Department of Pathology and Laboratory Medicine, University of Calgary, Arnie Charbonneau Cancer Institute

**Department of Pathology and Laboratory Medicine, University of Calgary, Calgary Laboratory Services, Foothills Medical Centre, Calgary, AB, Canada

¶Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Comprehensive Cancer Center (CCC) Erlangen-EMN, Erlangen, Germany

††Division of Clinical Medicine, Department of Histopathology, University of Surrey, Royal Surrey County Hospital, Guildford, Surrey

§§§Department of Cellular Pathology, University of Liverpool, Liverpool, UK

‡‡Department of Pathology, University of Alabama at Birmingham, Birmingham, AL

§§Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria

∥∥Department of Oral and Maxillofacial Pathology, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran

¶¶Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

##Department of Pathology, Warmia and Mazury University, Olsztyn

∥∥∥Department of Pathology, Medical University of Gdansk, Gdansk, Poland

†††Department of Histopathology, St. James’s Hospital & Dublin Dental Hospital, Trinity College Dublin, Dublin, Ireland

‡‡‡Division of Pathology, Department of Medical and Surgical Sciences for Children & Adults, University-Hospital of Modena and Reggio Emilia, Modena, Italy

¶¶¶Department of Pathology, Kenyatta National Hospital, Nairobi, Kenya

###Institute of Biomedicine, Pathology, University of Turku and Turku University Hospital, Turku, Finland

A.S. and I.L. are senior authors.

All procedures performed in this study involving human participants were in accordance with the ethical standards of the Ethics committee in Pilsen, September 6, 2020, Czech Republic.

The preliminary results of the study were presented as a poster presentation at the United States and Canadian Academy of Pathology’s 109th Annual Meeting in Los Angeles, CA, February 29-March 5, 2020.

Conflicts of Interest and Source of Funding: This study was in part supported by study grant SVV 260539 from the Ministry of Education, Czech Republic, the Cooperation Program, research area SURG, the project National Institute for Cancer Research—NICR (Programme EXCELES, ID Project No. LX22NPO5102). Funded by the European Union—Next Generation EU and the Finnish Cancer Society, Finska Läkaresällskapet, and Maritza and Reino Salonen Foundation, Finland. The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article.

Correspondence: Martina Baněčková, MD, PhD, Sikl’s Department of Pathology, Medical Faculty of Charles University, Faculty Hospital, E. Benese 13, 305 99 Plzen, Czech Republic (e-mail: [email protected]).

Supplemental Digital Content is available for this article. Direct URL citations are provided in the HTML and PDF versions of this article on the journal's website, www.ajsp.com.

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