Long-term follow-up after surgical management of laryngeal malignant pleomorphic sarcoma ‒ a case report

Laryngeal sarcomas are rare, comprising less than 1% of all laryngeal tumors. This study shed light on a case with Laryngeal Pleomorphic Sarcoma (LPS) and the five years follow-up results of the surgical management. Male patient aged 71 years presented to the emergency department with severe dyspnea and stridor. Endoscopic laryngeal examination revealed the presence of a trans-glottic exophytic mass encroaching the anterior commissure of both vocal folds with bilateral fixed vocal folds, and the respiratory chink was very narrow (Less than 1 cm). The patient underwent an urgent life-saving tracheostomy under general anesthesia. The operation also included microlaryngosurgery for tumor mapping and taking biopsies from the mass and the suspicious areas of the larynx. The histopathological examination indicated the diagnosis of LPS. Radiological imaging confirmed the tumor location and excluded extralaryngeal extension, lymph node involvement, and distant metastasis. The patient underwent a total laryngectomy without neck dissection. As the margins were free without local or remote spread, the patient did not receive radiotherapy. In the five-year follow-up, the patient was well-fit without any recurrence. It’s essential to define a multidisciplinary therapeutic approach to manage this malignancy. A long-term follow-up is necessary to monitor any recurrences and improve disease-free survival.

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