MiR-218-5p promotes trophoblast infiltration and inhibits endoplasmic reticulum/oxidative stress by reducing UBE3A-mediated degradation of SATB1

Ahmad IM, Zimmerman MC, Moore TA (2019) Oxidative stress in early pregnancy and the risk of preeclampsia. Pregnancy Hypertens 18:99–102. https://doi.org/10.1016/j.preghy.2019.09.014

Article  PubMed  PubMed Central  Google Scholar 

Aouache R, Biquard L, Vaiman D, Miralles F (2018) Oxidative stress in preeclampsia and placental diseases. Int J Mol Sci. https://doi.org/10.3390/ijms19051496

Article  PubMed  PubMed Central  Google Scholar 

Brkic J et al (2018) MicroRNA-218-5p promotes endovascular trophoblast differentiation and spiral artery remodeling. Mol Ther 26:2189–2205. https://doi.org/10.1016/j.ymthe.2018.07.009

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen M, Li M, Zhang N, Sun W, Wang H, Wei W (2021) Mechanism of miR-218–5p in autophagy, apoptosis and oxidative stress in rheumatoid arthritis synovial fibroblasts is mediated by KLF9 and JAK/STAT3 pathways. J Investig Med. https://doi.org/10.1136/jim-2020-001437

Article  PubMed  PubMed Central  Google Scholar 

Dong K, Zhang X, Ma L, Gao N, Tang H, Jian F, Ma Y (2019) Downregulations of circulating miR-31 and miR-21 are associated with preeclampsia. Pregnancy Hypertens 17:59–63. https://doi.org/10.1016/j.preghy.2019.05.013

Article  PubMed  Google Scholar 

Fang M et al (2017) Hypoxia-inducible microRNA-218 inhibits trophoblast invasion by targeting LASP1: implications for preeclampsia development. Int J Biochem Cell Biol 87:95–103. https://doi.org/10.1016/j.biocel.2017.04.005

Article  CAS  PubMed  Google Scholar 

Frazier S, McBride MW, Mulvana H, Graham D (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clin Sci (lond) 134:1001–1025. https://doi.org/10.1042/CS20200023

Article  CAS  PubMed  Google Scholar 

Jena MK, Sharma NR, Petitt M, Maulik D, Nayak NR (2020) Pathogenesis of preeclampsia and therapeutic approaches targeting the placenta. Biomolecules. https://doi.org/10.3390/biom10060953

Article  PubMed  PubMed Central  Google Scholar 

Liu S, Xie X, Lei H, Zou B, Xie L (2019) Identification of key circRNAs/lncRNAs/miRNAs/mRNAs and pathways in preeclampsia using bioinformatics analysis. Med Sci Monit 25:1679–1693. https://doi.org/10.12659/MSM.912801

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lopez SJ, Segal DJ, LaSalle JM (2018) UBE3A: an e3 ubiquitin ligase with genome-wide impact in neurodevelopmental disease. Front Mol Neurosci 11:476. https://doi.org/10.3389/fnmol.2018.00476

Article  CAS  PubMed  Google Scholar 

Lorigo M, Cairrao E (2022) Fetoplacental vasculature as a model to study human cardiovascular endocrine disruption. Mol Aspects Med 87:101054. https://doi.org/10.1016/j.mam.2021.101054

Article  CAS  PubMed  Google Scholar 

Lou CX, Zhou XT, Tian QC, Xie HQ, Zhang JY (2018) Low expression of microRNA-21 inhibits trophoblast cell infiltration through targeting PTEN. Eur Rev Med Pharmacol Sci 22:6181–6189. https://doi.org/10.26355/eurrev_201810_16023

Article  PubMed  Google Scholar 

Lv Y et al (2019) miR-145–5p promotes trophoblast cell growth and invasion by targeting FLT1. Life Sci 239:117008. https://doi.org/10.1016/j.lfs.2019.117008

Article  CAS  PubMed  Google Scholar 

Rao H, Bai Y, Zhang F, Li Q, Zhuang B, Luo X, Qi H (2019) The role of SATB1 in HTR8/SVneo cells and pathological mechanism of preeclampsia. J Matern Fetal Neonatal Med 32:2069–2078. https://doi.org/10.1080/14767058.2018.1425387

Article  CAS  PubMed  Google Scholar 

Rao H et al (2018) SATB1 downregulation induced by oxidative stress participates in trophoblast invasion by regulating beta-catenin. Biol Reprod 98:810–820. https://doi.org/10.1093/biolre/ioy033

Article  PubMed  Google Scholar 

Tian R, Wu B, Fu C, Guo K (2020) miR-137 prevents inflammatory response, oxidative stress, neuronal injury and cognitive impairment via blockade of Src-mediated MAPK signaling pathway in ischemic stroke. Aging (albany NY) 12:10873–10895. https://doi.org/10.18632/aging.103301

Article  CAS  PubMed  Google Scholar 

Torres-Odio S et al (2017) Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. J Neuroinflammation 14:154. https://doi.org/10.1186/s12974-017-0928-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang J et al (2019) UBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology. Proc Natl Acad Sci U S A 116:12500–12505. https://doi.org/10.1073/pnas.1820131116

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yan T et al (2014) Assessment of therapeutic efficacy of miR-126 with contrast-enhanced ultrasound in preeclampsia rats. Placenta 35:23–29. https://doi.org/10.1016/j.placenta.2013.10.017

Article  CAS  PubMed  Google Scholar 

Yang C, Song G, Lim W (2019) A mechanism for the effect of endocrine disrupting chemicals on placentation. Chemosphere 231:326–336. https://doi.org/10.1016/j.chemosphere.2019.05.133

Article  CAS  PubMed  Google Scholar 

Yang X, Chen D, He B, Cheng W (2021) NRP1 and MMP9 are dual targets of RNA-binding protein QKI5 to alter VEGF-R/ NRP1 signalling in trophoblasts in preeclampsia. J Cell Mol Med 25:5655–5670. https://doi.org/10.1111/jcmm.16580

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang Y et al (2020) Endoplasmic reticulum stress may activate NLRP3 inflammasomes via TXNIP in preeclampsia. Cell Tissue Res 379:589–599. https://doi.org/10.1007/s00441-019-03104-9

Article  CAS  PubMed  Google Scholar 

Yu L et al (2019) Reversible regulation of SATB1 ubiquitination by USP47 and SMURF2 mediates colon cancer cell proliferation and tumor progression. Cancer Lett 448:40–51. https://doi.org/10.1016/j.canlet.2019.01.039

Article  CAS  PubMed  Google Scholar 

Yuan Q, Xu T, Chen Y, Qu W, Sun D, Liu X, Sun L (2020) MiR-185–5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6. Lab Invest 100:1436–1446. https://doi.org/10.1038/s41374-020-0447-y

Article  CAS  PubMed  Google Scholar 

Zhang H et al (2020) miR-30–5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia. Redox Biol 29:101402. https://doi.org/10.1016/j.redox.2019.101402

Article  CAS  PubMed  Google Scholar 

Zhao X, Li Y, Chen S, Chen D, Shen H, Yang X, Cheng W (2020) Exosomal encapsulation of miR-125a-5p inhibited trophoblast cell migration and proliferation by regulating the expression of VEGFA in preeclampsia. Biochem Biophys Res Commun 525:646–653. https://doi.org/10.1016/j.bbrc.2020.02.137

Article  CAS  Google Scholar 

Zou AX, Chen B, Li QX, Liang YC (2018) MiR-134 inhibits infiltration of trophoblast cells in placenta of patients with preeclampsia by decreasing ITGB1 expression. Eur Rev Med Pharmacol Sci 22:2199–2206. https://doi.org/10.26355/eurrev_201804_14804

Article  PubMed  Google Scholar 

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