Mechanisms of systemic low-grade inflammation in HIV patients on long-term suppressive antiretroviral therapy: the inflammasome hypothesis

aUniversity Bordeaux, CNRS, ImmunoConcEpT, UMR 5164, INSERM ERL 1303

bUniversity Bordeaux, INSERM, Institut Bergonié, BPH, U1219, CIC-EC 1401

cCHU Bordeaux, Laboratory of Immunology and Immunogenetics

dCHU Bordeaux, Service de Médecine Interne et Immunologie Clinique

eCHU Bordeaux, Service de Médecine Interne

fCHU Bordeaux, Infectious and Tropical Diseases department

gCHU Bordeaux, Hôpital Saint-André, Service de Médecine Interne et Maladies Infectieuses

hINSERM U1211, 33000 Bordeaux, France; Bordeaux University; CELLOMET, Functional Genomics Center (CGFB), 146 rue Léo Saignat

iService Analyses Métaboliques TBMcore CNRS UAR 3427 INSERM US005 Université de Bordeaux, 1 rue Camille Saint-Saëns

jCHU Bordeaux, Laboratory of Virology

kCHU Bordeaux, Laboratory of Parasitology, Bordeaux

lINRIA SISTM team, Talence

mCHU de Bordeaux, Service d’information médicale, INSERM, Institut Bergonié, CIC-EC 1401, Bordeaux, France

nImmunology Discovery, Janssen Research & Development, San Diego, California, USA.

Correspondence to Florent Guerville, Univ. Bordeaux, CNRS, ImmunoConcEpT, UMR 5164, INSERM ERL 1303, 146 rue Léo Saignat, F-33000 Bordeaux, France. E-mail: [email protected]

Received 7 September, 2022

Revised 25 January, 2023

Accepted 23 February, 2023

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (http://www.AIDSonline.com).

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