Proteasome-independent K63 polyubiquitination selectively regulates ATP levels and proteasome activity during fear memory formation in the female amygdala

Christiansen DM, Berke ET. Gender- and sex-based contributors to sex differences in PTSD. Curr Psychiatry Rep. 2020;22:19.

Article  PubMed  Google Scholar 

Bedford L, Paine S, Sheppard PW, Mayer RJ, Roelofs J. Assembly, structure, and function of the 26S proteasome. Trends Cell Biol. 2010;20:391–401.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hegde AN. The ubiquitin-proteasome pathway and synaptic plasticity. Learn Mem. 2010;17:314–27.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Livneh I, Cohen-Kaplan V, Cohen-Rosenzweig C, Avni N, Ciechanover A. The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death. Cell Res. 2016;26:869–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akutsu M, Dikic I, Bremm A. Ubiquitin chain diversity at a glance. J Cell Sci. 2016;129:875–80.

CAS  PubMed  Google Scholar 

Dikic I, Wakatsuki S, Walters KJ. Ubiquitin-binding domains - from structures to functions. Nat Rev Mol Cell Biol. 2009;10:659–71.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Glickman MH, Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev. 2002;82:373–428.

Article  CAS  PubMed  Google Scholar 

Grice GL, Nathan JA. The recognition of ubiquitinated proteins by the proteasome. Cell Mol Life Sci. 2016;73:3497–506.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem. 1998;67:425–79.

Article  CAS  PubMed  Google Scholar 

Devulapalli R, Jones N, Farrell K, Musaus M, Kugler H, McFadden T, et al. Males and females differ in the regulation and engagement of, but not requirement for, protein degradation in the amygdala during fear memory formation. Neurobiol Learn Mem. 2021;180:107404.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Devulapalli RK, Nelsen JL, Orsi SA, McFadden T, Navabpour S, Jones N, et al. Males and Females Differ in the Subcellular and Brain Region Dependent Regulation of Proteasome Activity by CaMKII and Protein Kinase A. Neuroscience. 2019;418:1–14.

Article  CAS  PubMed  Google Scholar 

Farrell K, Musaus M, Navabpour S, Martin K, Ray WK, Helm RF, et al. Proteomic Analysis Reveals Sex-Specific Protein Degradation Targets in the Amygdala During Fear Memory Formation. Front Mol Neurosci. 2021;14:716284.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martin K, Musaus M, Navabpour S, Gustin A, Ray WK, Helm RF, et al. Females, but not males, require protein degradation in the hippocampus for contextual fear memory formation. Learn Mem. 2021;28:248–53.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Musaus M, Farrell K, Navabpour S, Ray WK, Helm RF, Jarome TJ. Sex-specific linear polyubiquitination is a critical regulator of contextual fear memory formation. Front Behav Neurosci. 2021;15:709392.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dulka BN, Trask S, Helmstetter FJ. Age-related memory impairment and sex-specific alterations in phosphorylation of the Rpt6 Proteasome subunit and Polyubiquitination in the basolateral Amygdala and medial prefrontal cortex. Front Aging Neurosci. 2021;13:656944.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Erpapazoglou Z, Walker O, Haguenauer-Tsapis R. Versatile roles of k63-linked ubiquitin chains in trafficking. Cells. 2014;3:1027–88.

Article  PubMed  PubMed Central  Google Scholar 

Lee BL, Singh A, Mark Glover JN, Hendzel MJ, Spyracopoulos L. Molecular Basis for K63-Linked Ubiquitination Processes in Double-Strand DNA Break Repair: A Focus on Kinetics and Dynamics. J Mol Biol. 2017;429:3409–29.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nathan JA, Kim HT, Ting L, Gygi SP, Goldberg AL. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? EMBO J. 2013;32:552–65.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cox DBT, Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, et al. RNA editing with CRISPR-Cas13. Science. 2017;358:1019–27.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Melfi R, Cancemi P, Chiavetta R, Barra V, Lentini L, Di Leonardo A. Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons. Int J Mol Sci. 2020;21:4781.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jarome TJ, Perez GA, Webb WM, Hatch KM, Navabpour S, Musaus M, et al. Ubiquitination of Histone H2B by Proteasome Subunit RPT6 Controls Histone Methylation Chromatin Dynamics During Memory Formation. Biol Psychiatry. 2021;89:1176–87.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jarome TJ, Kwapis JL, Ruenzel WL, Helmstetter FJ. CaMKII, but not protein kinase A, regulates Rpt6 phosphorylation and proteasome activity during the formation of long-term memories. Front Behav Neurosci. 2013;7:115.

PubMed  PubMed Central  Google Scholar 

Jarome TJ, Werner CT, Kwapis JL, Helmstetter FJ. Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala. PLoS One. 2011;6:e24349.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Orsi SA, Devulapalli RK, Nelsen JL, McFadden T, Surineni R, Jarome TJ. Distinct subcellular changes in proteasome activity and linkage-specific protein polyubiquitination in the amygdala during the consolidation and reconsolidation of a fear memory. Neurobiol Learn Mem. 2019;157:1–11.

Article  CAS  PubMed  Google Scholar 

Johansen JP, Cain CK, Ostroff LE, LeDoux JE. Molecular mechanisms of fear learning and memory. Cell. 2011;147:509–24.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zalcman G, Federman N, Romano A. CaMKII isoforms in learning and memory: Localization and function. Front Mol Neurosci. 2018;11:445.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ohtake F, Tsuchiya H, Saeki Y, Tanaka K. K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains. Proc Natl Acad Sci USA. 2018;115:E1401–e1408.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bauer EP, Schafe GE, LeDoux JE. NMDA receptors and L-type voltage-gated calcium channels contribute to long-term potentiation and different components of fear memory formation in the lateral amygdala. J Neurosci. 2002;22:5239–49.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jarome TJ, Helmstetter FJ. The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. Neurobiol Learn Mem. 2013;105:107–16.

Article  CAS  PubMed  PubMed Central  Google Scholar 

López AJ, Hecking JK, White AO. The Emerging Role of ATP-dependent chromatin remodeling in memory and substance use disorders. Int J Mol Sci. 2020;21:6816.

Article  PubMed  PubMed Central  Google Scholar 

Rangaraju V, Calloway N, Ryan TA. Activity-driven local ATP synthesis is required for synaptic function. Cell. 2014;156:825–35.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rodrigues SM, Schafe GE, LeDoux JE. Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning. J Neurosci. 2001;21:6889–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang CM, Yang YJ, Zhang JT, Liu J, Guan XL, Li MX, et al. Regulation of emotional memory by hydrogen sulfide: role of GluN2B-containing NMDA receptor in the amygdala. J Neurochem. 2015;132:124–34.

Article  CAS  PubMed  Google Scholar 

Nakazawa T, Komai S, Watabe AM, Kiyama Y, Fukaya M, Arima-Yoshida F, et al. NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. EMBO J. 2006;25:2867–77.

Article  CAS  PubMed  PubMed Central

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