Carr AC, Frei B (1999) Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am J Clin Nutr 69(6):1086–1107. https://doi.org/10.1093/ajcn/69.6.1086
Article CAS PubMed Google Scholar
Oudemans-van Straaten HM, Spoelstra-de Man AM, de Waard MC (2014) Vitamin C revisited. Crit Care 18(4):460. https://doi.org/10.1186/s13054-014-0460-x
Article PubMed PubMed Central Google Scholar
Khaw KT, Bingham S, Welch A et al (2001) Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition. Lancet 357(9257):657–663. https://doi.org/10.1016/s0140-6736(00)04128-3
Article CAS PubMed Google Scholar
Martín-Calvo N, Martínez-González M (2017) Vitamin C intake is inversely associated with cardiovascular mortality in a cohort of Spanish graduates: the SUN Project. Nutrients. https://doi.org/10.3390/nu9090954
Article PubMed PubMed Central Google Scholar
Goyal A, Terry MB, Siegel AB (2013) Serum antioxidant nutrients, vitamin A, and mortality in US adults. Cancer Epidemiol Biomark Prev 22(12):2202–2211. https://doi.org/10.1158/1055-9965.EPI-13-0381
Tian T, Shao J, Shen Z et al (2022) Association of serum vitamin C with all-cause and cause-specific death: Data from National Health and Nutrition Examination Survey (NHANES 2003–2006). Nutrition 101:111696. https://doi.org/10.1016/j.nut.2022.111696
Buijsse B, Feskens EJ, Kwape L et al (2008) Both alpha- and beta-carotene, but not tocopherols and vitamin C, are inversely related to 15-year cardiovascular mortality in Dutch elderly men. J Nutr 138(2):344–350. https://doi.org/10.1093/jn/138.2.344
Article CAS PubMed Google Scholar
Zheng JS, Sharp SJ, Imamura F et al (2020) Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries. BMJ 370:m2194. https://doi.org/10.1136/bmj.m2194
Article PubMed PubMed Central Google Scholar
Aune D, Giovannucci E, Boffetta P et al (2017) Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality—a systematic review and dose-response meta-analysis of prospective studies. Int J Epidemiol 46(3):1029–1056. https://doi.org/10.1093/ije/dyw319
Article PubMed PubMed Central Google Scholar
Stepaniak U, Micek A, Grosso G et al (2016) Antioxidant vitamin intake and mortality in three Central and Eastern European urban populations: the HAPIEE study. Eur J Nutr 55(2):547–560. https://doi.org/10.1007/s00394-015-0871-8
Article CAS PubMed Google Scholar
Gey KF (1995) Ten-year retrospective on the antioxidant hypothesis of arteriosclerosis: threshold plasma levels of antioxidant micronutrients related to minimum cardiovascular risk. J Nutr Biochem 6(4):206–236
Urakawa H, Katsuki A, Sumida Y et al (2003) Oxidative stress is associated with adiposity and insulin resistance in men. J Clin Endocrinol Metab 88(10):4673–4676. https://doi.org/10.1210/jc.2003-030202
Article CAS PubMed Google Scholar
Wilson R, Willis J, Gearry R et al (2017) Inadequate vitamin C status in prediabetes and type 2 diabetes mellitus: associations with glycaemic control, obesity, and smoking. Nutrients 9(9):997. https://doi.org/10.3390/nu9090997
Article CAS PubMed PubMed Central Google Scholar
Yaribeygi H, Sathyapalan T, Atkin SL, Sahebkar A (2020) Molecular mechanisms linking oxidative stress and diabetes mellitus. Oxid Med Cell Longev 2020:8609213. https://doi.org/10.1155/2020/8609213
Article CAS PubMed PubMed Central Google Scholar
Mullan BA, Young IS, Fee H, McCance DR (2002) Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes. Hypertension 40(6):804–809. https://doi.org/10.1161/01.hyp.0000039961
Article CAS PubMed Google Scholar
Mason SA, Rasmussen B, van Loon LJC et al (2019) Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: findings of a randomized cross-over trial. Diabetes Obes Metab 21(3):674–682. https://doi.org/10.1111/dom.13571
Article CAS PubMed Google Scholar
Mason SA, Keske MA, Wadley GD (2021) Effects of vitamin C supplementation on glycemic control and cardiovascular risk factors in people with type 2 diabetes: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials. Diabetes Care 44(2):618–630. https://doi.org/10.2337/dc20-1893
Article CAS PubMed Google Scholar
Chen H, Karne RJ, Hall G et al (2006) High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance. Am J Physiol Heart Circ Physiol 290(1):H137-145. https://doi.org/10.1152/ajpheart.00768.2005
Article CAS PubMed Google Scholar
Dehghan M, Akhtar-Danesh N, McMillan CR, Thabane L (2007) Is plasma vitamin C an appropriate biomarker of vitamin C intake? A systematic review and meta-analysis. Nutr J 6:41. https://doi.org/10.1186/1475-2891-6-41
Article CAS PubMed PubMed Central Google Scholar
Centers for Disease Control and Prevention (2006) The National Health and Nutritional Examination Survey (NHANES) analytic and reporting guidelines. CDC, Atlanta. https://wwwn.cdc.gov/Nchs/Nhanes/AnalyticGuidelines.aspx. Accessed 30 Oct 2022
Margolis SA, Duewer DL (1996) Measurement of ascorbic acid in human plasma and serum: stability, intralaboratory repeatability, and interlaboratory reproducibility. Clin Chem 42(8 Pt 1):1257–1262
Article CAS PubMed Google Scholar
Beddhu S, Baird BC, Zitterkoph J et al (2009) Physical activity and mortality in chronic kidney disease (NHANES III). Clin J Am Soc Nephrol 4(12):1901–1906. https://doi.org/10.2215/CJN.01970309
Article PubMed PubMed Central Google Scholar
Haytowitz DB, Ahuja JK, Wu X et al (2019) USDA National Nutrient Database for standard reference, legacy release. Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, ARS, USDA. https://data.nal.usda.gov/dataset/usda-national-nutrient-database-standard-reference-legacy-release. Accessed 30 Oct 2022
Matthews DR, Hosker JP, Rudenski AS et al (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28(7):412–419. https://doi.org/10.1007/BF00280883
Article CAS PubMed Google Scholar
Yung YF, Lamm M, Zhang W (2018) Causal mediation analysis with the CAUSALMED procedure. SAS Institute Inc, USA. https://www.sas.com/content/dam/SAS/support/en/sas-global-forum-proceedings/2018/1991-2018.pdf. Accessed 30 Oct 2022
Agudo A, Cabrera L, Amiano P et al (2007) Fruit and vegetable intakes, dietary antioxidant nutrients, and total mortality in Spanish adults: findings from the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain). Am J Clin Nutr 85(6):1634–1642. https://doi.org/10.1093/ajcn/85.6.1634
Article CAS PubMed Google Scholar
Loria CM, Klag MJ, Caulfield LE, Whelton PK (2000) Vitamin C status and mortality in US adults. Am J Clin Nutr 72(1):139–145. https://doi.org/10.1093/ajcn/72.1.139
Article CAS PubMed Google Scholar
Mason SA, Della Gatta PA, Snow RJ et al (2016) Ascorbic acid supplementation improves skeletal muscle oxidative stress and insulin sensitivity in people with type 2 diabetes: findings of a randomized controlled study. Free Radic Biol Med 93:227–238. https://doi.org/10.1016/j.freeradbiomed.2016.01.006
Article CAS PubMed Google Scholar
Upritchard JE, Sutherland WH, Mann JI (2000) Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes. Diabetes Care 23(6):733–738. https://doi.org/10.2337/diacare.23.6.733
Article CAS PubMed Google Scholar
Lee DH, Folsom AR, Harnack L et al (2004) Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes? Am J Clin Nutr 80(5):1194–1200. https://doi.org/10.1093/ajcn/80.5.1194
Article CAS PubMed Google Scholar
Aune D, Keum N, Giovannucci E et al (2018) Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose–response meta-analysis of prospective studies. Am J Clin Nutr 108(5):1069–1091. https://doi.org/10.1093/ajcn/nqy097
Article PubMed PubMed Central Google Scholar
Fletcher AE, Breeze E, Shetty PS (2003) Antioxidant vitamins and mortality in older persons: findings from the nutrition add-on study to the Medical Research Council Trial of assessment and management of older people in the community. Am J Clin Nutr 78(5):999–1010. https://doi.org/10.1093/ajcn/78.5.999
Article CAS PubMed Google Scholar
Schleicher RL, Carroll MD, Ford ES, Lacher DA (2009) Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003–2004 National Health and Nutrition Examination Survey (NHANES). Am J Clin Nutr 90(5):1252–1263. https://doi.org/10.3945/ajcn.2008.27016
Article CAS PubMed Google Scholar
Padayatty SJ, Katz A, Wang Y et al (2003) Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr 22(1):18–35. https://doi.org/10.1080/07315724.2003
Article CAS PubMed Google Scholar
Chen Q, Espey MG, Sun AY et al (2007) Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo. Proc Natl Acad Sci USA 104(21):8749–8754. https://doi.org/10.1073/pnas.0702854104
Article CAS PubMed PubMed Central Google Scholar
Bouayed J, Bohn T (2010) Exogenous antioxidants–double-edged swords in cellular redox state: health beneficial effects at physiologic doses versus deleterious effects at high doses. Oxid Med Cell Longev 3(4):228–237. https://doi.org/10.4161/oxim.3.4.12858
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