Tumour microenvironment and pituitary tumour behaviour

Kasuki L, Raverot G (2020) Definition and diagnosis of aggressive pituitary tumors. Rev Endocr Metab Disord 21(2):203–208

Article  PubMed  Google Scholar 

Molitch ME (2017) Diagnosis and treatment of pituitary adenomas: a review. JAMA 317(5):516–524

Article  PubMed  Google Scholar 

Drake LE, Macleod KF (2014) Tumour suppressor gene function in carcinoma-associated fibroblasts: from tumour cells via EMT and back again? J Pathol 232(3):283–288

Article  CAS  PubMed  PubMed Central  Google Scholar 

Balkwill FR (2012) The chemokine system and cancer. J Pathol 226(2):148–157

Article  CAS  PubMed  Google Scholar 

Balkwill FR, Capasso M, Hagemann T (2012) The tumor microenvironment at a glance. J Cell Sci 125(Pt 23):5591–5596

Article  CAS  PubMed  Google Scholar 

Ilie MD, Vasiljevic A, Raverot G, Bertolino P (2019) The microenvironment of pituitary tumors-biological and therapeutic implications. Cancers (Basel) 11(10):1605

Article  CAS  PubMed  Google Scholar 

Marques P, Grossman AB, Korbonits M (2020) The tumour microenvironment of pituitary neuroendocrine tumours. Front Neuroendocrinol 58:100852

Article  CAS  PubMed  Google Scholar 

Marques P, Barry S, Carlsen E, Collier D, Ronaldson A, Awad S, Dorward N, Grieve J, Mendoza N, Muquit S, Grossman AB, Balkwill F, Korbonits M (2019) Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours. Acta Neuropathol Commun 7(1):172

Article  PubMed  PubMed Central  Google Scholar 

Marques P, Barry S, Carlsen E, Collier D, Ronaldson A, Awad S, Dorward N, Grieve J, Mendoza N, Muquit S, Grossman AB, Balkwill F, Korbonits M (2019) Pituitary tumour fibroblast-derived cytokines influence tumour aggressiveness. Endocr Relat Cancer 26(12):853–865

Article  CAS  PubMed  Google Scholar 

Principe M, Chanal M, Ilie MD, Ziverec A, Vasiljevic A, Jouanneau E, Hennino A, Raverot G, Bertolino P (2020) Immune landscape of pituitary tumors reveals association between macrophages and gonadotroph tumor invasion. J Clin Endocrinol Metab 105(11):dgaa520

Article  PubMed  Google Scholar 

Marques P, Silva AL, Lopez-Presa L, Faria C, Bugalho MJ (2022) The microenvironment of pituitary adenomas: biological, clinical and therapeutical implications. Pituitary 25(3):363–382

Article  PubMed  Google Scholar 

Chiloiro S, De Marinis L (2023) The immune microenviroment in somatotropinomas: from biology to personalized and target therapy. Rev Endocr Metab Disord 24(2):283–295

Article  PubMed  PubMed Central  Google Scholar 

Marques P, Barry S, Carlsen E, Collier D, Ronaldson A, Dorward N, Grieve J, Mendoza N, Nair R, Muquit S, Grossman AB, Korbonits M (2020) The role of the tumour microenvironment in the angiogenesis of pituitary tumours. Endocrine 70(3):593–606

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gasser S, Lim LHK, Cheung FSG (2017) The role of the tumour microenvironment in immunotherapy. Endocr Relat Cancer 24(12):T283–T295

Article  CAS  PubMed  Google Scholar 

Dai C, Liang S, Sun B, Kang J (2020) The progress of immunotherapy in refractory pituitary adenomas and pituitary carcinomas. Front Endocrinol (Lausanne) 11:608422

Article  PubMed  Google Scholar 

Iacovazzo D, Chiloiro S, Carlsen E, Bianchi A, Giampietro A, Tartaglione T, Bima C, Bracaccia ME, Lugli F, Lauretti L, Anile C, Gessi M, Colosimo C, Rindi G, Pontecorvi A, Korbonits M, De Marinis L (2019) Tumour-infiltrating cytotoxic T lymphocytes in somatotroph pituitary neuroendocrine tumours. Endocrine 67(3):651–658

Article  PubMed  PubMed Central  Google Scholar 

Lu JQ, Adam B, Jack AS, Lam A, Broad RW, Chik CL (2015) Immune cell infiltrates in pituitary adenomas: more macrophages in larger adenomas and more T cells in growth hormone adenomas. Endocr Pathol 26(3):263–272

Article  CAS  PubMed  Google Scholar 

Zhang A, Xu Y, Xu H, Ren J, Meng T, Ni Y, Zhu Q, Zhang WB, Pan YB, Jin J, Bi Y, Wu ZB, Lin S, Lou M (2021) Lactate-induced M2 polarization of tumor-associated macrophages promotes the invasion of pituitary adenoma by secreting CCL17. Theranostics 11(8):3839–3852

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsuzaki H, Komohara Y, Yano H, Fujiwara Y, Kai K, Yamada R, Yoshii D, Uekawa K, Shinojima N, Mikami Y, Mukasa A (2022) Macrophage colony-stimulating factor potentially induces recruitment and maturation of macrophages in recurrent pituitary neuroendocrine tumors. Microbiol Immunol 67(2):90–98

Article  PubMed  Google Scholar 

Yeung JT, Vesely MD, Miyagishima DF (2020) In silico analysis of the immunological landscape of pituitary adenomas. J Neurooncol 147(3):595–598

Article  PubMed  PubMed Central  Google Scholar 

Zhou W, Zhang C, Zhang D, Peng J, Ma S, Wang X, Guan X, Li P, Li D, Jia G, Jia W (2020) Comprehensive analysis of the immunological landscape of pituitary adenomas: implications of immunotherapy for pituitary adenomas. J Neurooncol 149(3):473–487

Article  CAS  PubMed  Google Scholar 

Wang Z, Guo X, Gao L, Deng K, Lian W, Bao X, Feng M, Duan L, Zhu H, Xing B (2020) The immune profile of pituitary adenomas and a novel immune classification for predicting immunotherapy responsiveness. J Clin Endocrinol Metab 105(9):e3207–e3223

Article  PubMed  PubMed Central  Google Scholar 

Lyu L, Jiang Y, Ma W, Li H, Liu X, Li L, Shen A, Yu Y, Jiang S, Li H, Zhou P, Yin S (2023) Single-cell sequencing of PIT1-positive pituitary adenoma highlights the pro-tumour microenvironment mediated by IFN-gamma-induced tumour-associated fibroblasts remodelling. Br J Cancer 128(6):1117–1133

Article  PubMed  Google Scholar 

Wang Z, Chang M, Zhang Y, Zhou G, Liu P, Lou J, Wang Y, Zhang Y, Guo X, Wang Y, Bao X, Lian W, Wang Y, Wang R, Ma W, Xing B, Gao J (2022) Multi-omics investigations revealed underlying molecular mechanisms associated with tumor stiffness and identified sunitinib as a potential therapy for reducing stiffness in pituitary adenomas. Front Cell Dev Biol 10:820562

Article  PubMed  PubMed Central  Google Scholar 

Zhang D, Hugo W, Bergsneider M, Wang MB, Kim W, Vinters HV, Heaney AP (2022) Single-cell RNA sequencing in silent corticotroph tumors confirms impaired POMC processing and provides new insights into their invasive behavior. Eur J Endocrinol 187(1):49–64

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nie D, Fang Q, Li B, Cheng J, Li C, Gui S, Zhang Y, Zhao P (2021) Research advances on the immune research and prospect of immunotherapy in pituitary adenomas. World J Surg Oncol 19(1):162

Article  PubMed  PubMed Central  Google Scholar 

Mei Y, Bi WL, Agolia J, Hu C, Giantini Larsen AM, Meredith DM, Al Abdulmohsen S, Bale T, Dunn GP, Abedalthagafi M, Dunn IF (2021) Immune profiling of pituitary tumors reveals variations in immune infiltration and checkpoint molecule expression. Pituitary 24(3):359–373

Article  CAS  PubMed  Google Scholar 

Rossi ML, Jones NR, Esiri MM, Havas L, al IzziCoakham MHB (1990) Mononuclear cell infiltrate and HLA-Dr expression in 28 pituitary adenomas. Tumori 76(6):543–547

Article  CAS  PubMed  Google Scholar 

Heshmati HM, Kujas M, Casanova S, Wollan PC, Racadot J, Van Effenterre R, Derome PJ, Turpin G (1998) Prevalence of lymphocytic infiltrate in 1400 pituitary adenomas. Endocr J 45(3):357–361

Article  CAS  PubMed  Google Scholar 

Jacobs JF, Idema AJ, Bol KF, Nierkens S, Grauer OM, Wesseling P, Grotenhuis JA, Hoogerbrugge PM, de Vries IJ, Adema GJ (2009) Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors. Neuro Oncol 11(4):394–402

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chiloiro S, Giampietro A, Gessi M, Lauretti L, Mattogno P, Cerroni L, Carlino A, De Alessandris Q, Olivi A, Rindi G, Pontecorvi A, De Marinis L, Doglietto F, Bianchi A (2023) CD68+ and CD8+ immune cells are associated to the growth pattern of somatotroph tumors and to the response to first generation somatostatin analogues. J Neuroendocrinol. https://doi.org/10.1111/jne.13263

Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C, Solomou A, Herincs M, Caimari F, Grossman AB, Crnogorac-Jurcevic T, Haworth O, Gaston-Massuet C, Korbonits M (2019) Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors. Oncogene 38(27):5381–5395

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fujiwara K, Yatabe M, Tofrizal A, Jindatip D, Yashiro T, Nagai R (2017) Identification of M2 macrophages in anterior pituitary glands of normal rats and rats with estrogen-induced prolactinoma. Cell Tissue Res 368(2):371–378

Article  CAS  PubMed  Google Scholar 

Mantovani A, Schioppa T, Porta C, Allavena P, Sica A (2006) Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev 25(3):315–322

Article  PubMed  Google Scholar 

Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23(11):549–555

Article  CAS  PubMed 

留言 (0)

沒有登入
gif