Y. Gao, P. Wang, J. Lu, B. Pan, D. Guo, Z. Zhang, A. Wang, M. Zhang, J. Sun, W. Wang, Z. Liang, Diagnostic significance of parafibromin expression in parathyroid carcinoma. Hum. Pathol. 127, 28–38 (2022). https://doi.org/10.1016/j.humpath.2022.05.014
Article CAS PubMed Google Scholar
S. Leonard-Murali, T. Ivanics, D.S. Kwon, X. Han, C.P. Steffes, R. Shah, Local resection versus radical surgery for parathyroid carcinoma: a national cancer database analysis. Eur. J. Surg. Oncol. 47, 2768–2773 (2021). https://doi.org/10.1016/j.ejso.2021.06.026
Article PubMed PubMed Central Google Scholar
W.M. Lo, M.L. Good, N. Nilubol, N.D. Perrier, D.T. Patel, Tumor size and presence of metastatic disease at diagnosis are associated with disease-specific survival in parathyroid carcinoma. Ann. Surg. Oncol. 25, 2535–2540 (2018). https://doi.org/10.1245/s10434-018-6559-6
Article PubMed PubMed Central Google Scholar
L.K. Long, R.S. Sippel, Current and future treatment for parathyroid carcinoma. Int. J. Endo. Oncol. 5(1), IJE06 (2018). https://doi.org/10.2217/ije-2017-0011
C.N. Clarke, P. Katsonis, T.K. Hsu, A.M. Koire, A. Silva-Figueroa, I. Christakis, M.D. Williams, M. Kutahyalioglu, L. Kwatampora, Y. Xi, J.E. Lee, E.S. Koptez, N.L. Busaidy, N.D. Perrier, O. Lichtarge, Comprehensive genomic characterization of parathyroid cancer identifies novel candidate driver mutations and core pathways. J. Endocr. Soc. 3(3), 544–559 (2018). https://doi.org/10.1210/js.2018-00043
Article CAS PubMed PubMed Central Google Scholar
F. Marini, F. Giusti, G. Palmini, G. Perigli, R. Santoro, M.L. Brandi, Genetics and epigenetics of parathyroid carcinoma. Front. Endocrinol. 13, 834362 (2022). https://doi.org/10.3389/fendo.2022.834362
N.D. Perrier, A. Arnold, J. Costa-Guda, N.L. Busaidy, H. Nguyen, H.H. Chuang, M.L. Brandi, Hereditary endocrine tumours: current state-of-the-art and research opportunities: new and future perspectives for parathyroid carcinoma. Endocr. Relat. Cancer 27(8), T53–T63 (2020). https://doi.org/10.1530/ERC-20-0018
R. Uljanovs, S. Sinkarevs, B. Strumfs, L. Vidusa, K. Merkurjeva, I. Strumfa, Immunohistochemical profile of parathyroid tumours: a comprehensive review. Int. J. Mol. Sci. 23(13), 6981 (2022). https://doi.org/10.3390/ijms23136981
Article CAS PubMed PubMed Central Google Scholar
C. Pandya, A.V. Uzilov, J. Bellizzi, C.Y. Lau, A.S. Moe, M. Strahl, W. Hamou, L.C. Newman, M.Y. Fink, Y. Antipin, W. Yu, M. Stevenson, B.M. Cavaco, B.T. The, R.V. Thakker, H. Morreau, E.E. Schadt, R. Sebra, S.D. Li, A. Arnold, R. Chen, Genomic profiling reveals mutational landscape in parathyroid carcinomas. Jci. Insight 2(6), e92061 (2017). https://doi.org/10.1172/jci.insight.92061
Article PubMed PubMed Central Google Scholar
L. Zhao, L.H. Sun, D.M. Liu, X.Y. He, B. Tao, G. Ning, J.M. Liu, H.Y. Zhao, Copy number variation in CCND1 gene is implicated in the pathogenesis of sporadic parathyroid carcinoma. World J. Surg. 38(7), 1730–1737 (2014). https://doi.org/10.1007/s00268-014-2455-9
H.S. Park, Y.H. Lee, N. Hong, D. Won, Y. Rhee, Germline mutations related to primary hyperparathyroidism identified by next-generation sequencing. Front. Endocrinol. 13, 853171 (2022). https://doi.org/10.3389/fendo.2022.853171
Y. Hu, X. Zhang, O. Wang, Y. Bi, X. Xing, M. Cui, M. Wang, W. Tao, Q. Liao, Y. Zhao, The genomic profile of parathyroid carcinoma based on whole-genome sequencing. Int. J. Cancer 147(9), 2446–2457 (2020). https://doi.org/10.1002/ijc.33166
Article CAS PubMed Google Scholar
H. Kang, D. Pettinga, A.D. Schubert, P.W. Ladenson, D.W. Ball, J.H. Chung, A.B. Schrock, R. Madison, G.M. Frampton, P.J. Stephens, J.S. Ross, V.A. Miller, S.M. Ali, Genomic profiling of parathyroid carcinoma reveals genomic alterations suggesting benefit from therapy. Oncologist 24(6), 791–797 (2019). https://doi.org/10.1634/theoncologist.2018-0334
Article CAS PubMed Google Scholar
M. Kutahyalioglu, H.T. Nguyen, L. Kwatampora, C. Clarke, A. Silva, E. Ibrahim, S.G. Waguespack, M.E. Cabanillas, C. Jimenez, M.I. Hu, S.I. Sherman, S. Kopetz, R. Broaddus, R. Dadu, K. Wanland, M. Williams, M. Zafereo, N. Perrier, N.L. Busaidy, Genetic profiling as a clinical tool in advanced parathyroid carcinoma. J. Cancer Res. Clin. Oncol. 145(8), 1977–1986 (2019)
H.L. Robbins, A. Hague, The PI3K/Akt pathway in tumors of endocrine tissues. Front. Endocrinol. 6, 188 (2015). https://doi.org/10.1007/s00432-019-02945-9
S.H. Kong, Updates of genomics and proteomics of parathyroid carcinoma. Endocrines 3, 745–752 (2022). https://doi.org/10.3390/endocrines3040061
A. Riccardi, C. Lemos, R. Ramos, J. Bellizzi, K. Parham, T.C. Brown, R. Korah, T. Carling, J. Costa-Guda, A. Arnold, PIK3CA mutational analysis of parathyroid adenomas. JBMR 4(6), e10360 (2020). https://doi.org/10.1002/jbm4.10360
T. Zhan, N. Rindtorff, M. Boutros, Wnt signaling in cancer. Oncogene 36, 1461–1473 (2017). https://doi.org/10.1038/onc.2016.304
Article CAS PubMed Google Scholar
J. Svedlund, M. Aurén, M. Sundström, H. Dralle, G. Akerström, P. Björklund, G. Westin, Aberrant WNT/β-catenin signaling in parathyroid carcinoma. Mol. Cancer 9, 294 (2010). https://doi.org/10.1186/1476-4598-9-294
Article CAS PubMed PubMed Central Google Scholar
J. Svedlund, E. Barazeghi, P. Stålberg, P. Hellman, G. Åkerström, P. Björklund, G. Westin, The histone methyltransferase EZH2, an oncogene common to benign and malignant parathyroid tumors. Endocr. Relat. Cancer 21(2), 231–239 (2014). https://doi.org/10.1530/ERC-13-0497
Article CAS PubMed Google Scholar
L. Sulaiman, C.C. Juhlin, I.L. Nilsson, O. Fotouhi, C. Larsson, J. Hashemi, Global and gene-specific promoter methylation analysis in primary hyperparathyroidism. Epigenetics 8, 646–655 (2013). https://doi.org/10.4161/epi.24823
Article CAS PubMed PubMed Central Google Scholar
L.F. Starker, J. Svedlund, R. Udelsman, H. Dralle, G. Akerström, G. Westin, R.P. Lifton, P. Björklund, T. Carling, The DNA methylome of benign and malignant parathyroid tumors. Genes. Chromosomes Cancer 50, 735–745 (2011). https://doi.org/10.1002/gcc.20895
Article CAS PubMed PubMed Central Google Scholar
C.C. Juhlin, N.B. Kiss, A. Villablanca, F. Haglund, J. Nordenström, A. Höög, C. Larsson, Frequent promoter hypermethylation of the APC and RASSF1A tumour suppressors in parathyroid tumours. PLoS ONE 5, e9472 (2010). https://doi.org/10.1371/journal.pone.0009472
Article CAS PubMed PubMed Central Google Scholar
J. Svedlund, S. Koskinen Edblom, V.E. Marquez, G. Åkerström, P. Björklund, G. Westin, Hypermethylated in cancer 1 (HIC1), a tumor suppressor gene epigenetically deregulated in hyperparathyroid tumors by histone H3 lysine modification. J. Clin. Endocrinol. Metab. 2012(97), E1307–E1315 (2012). https://doi.org/10.1210/jc.2011-3136
S. Corbetta, V. Vaira, V. Guarnieri, A. Scillitani, C. Eller-Vainicher, S. Ferrero, L. Vicentini, I. Chiodini, M. Bisceglia, P. Beck-Peccoz, S. Bosari, A. Spada, Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue. Endocr. Relat. Cancer 17(1), 135–146 (2010). https://doi.org/10.1677/ERC-09-0134
Article CAS PubMed Google Scholar
S. Liu, Z. Wang, Z. Liu, S. Shi, Z. Zhang, J. Zhang, H. Lin, miR-221/222 activate the Wnt/β-catenin signaling to promote triple-negative breast cancer. J. Mol. Cell. Biol. 10(4), 302–315 (2018). https://doi.org/10.1093/jmcb/mjy041
Article CAS PubMed Google Scholar
F. Marini, F. Giusti, G. Palmini, C. Aurilia, S. Donati, M.L. Brandi, Parathyroid carcinoma: update on pathogenesis and therapy. Endocrines 4(1), 205–235 (2023). https://doi.org/10.3390/endocrines4010018
B. Guan, J.M. Welch, J.C. Sapp, H. Ling, Y. Li, J.J. Johnston, E. Kebebew, L.G. Biesecker, W.F. Simonds, S.J. Marx, S.K. Agarwal, GCM2-activating mutations in familial isolated hyperparathyroidism. Am. J. Hum. Genet. 99(5), 1034–1044 (2016). https://doi.org/10.1016/j.ajhg.2016.08.018
Article CAS PubMed PubMed Central Google Scholar
L. Canaff, V. Guarnieri, Y. Kim, B.Y.L. Wong, A. Nolin-Lapalme, D.E.C. Cole, S. Minisola, C. Eller-Vainicher, F. Cetani, A. Repaci, D. Turchetti, S. Corbetta, A. Scillitani, D. Goltzman, Novel Glial Cells Missing-2 (GCM2) variants in parathyroid disorders. Eur. J. Endocrinol. 186(3), 351–366 (2022). https://doi.org/10.1016/10.1530/EJE-21-0433
Article CAS PubMed PubMed Central Google Scholar
A. Song, Y. Yang, Y. Wang, S. Liu, M. Nie, Y. Jiang, M. Li, W. Xia, O. Wang, X. Xing, Germline GCM2 Mutation Screening in Chinese Primary Hyperparathyroidism Patients. Endocr. Pract. 26(10), 1093–1104 (2020). https://doi.org/10.4158/EP-2020-0132
R. Rahbari, A.K. Holloway, M. He, E. Khanafshar, O.H. Clark, E. Kebebew, Identification of differentially expressed microRNA in parathyroid tumors. Ann. Surg. Oncol. 18(4), 1158–1165 (2011). https://doi.org/10.1245/s10434-010-1359-7
J. Krupinova, N. Mokrysheva, V. Petrov, E. Pigarova, A. Eremkina, E. Dobreva, A. Ajnetdinova, G. Melnichenko, A. Tiulpakov, Serum circulating miRNA-342-3p as a potential diagnostic biomarker in parathyroid carcinomas: a pilot study. Endocrinol. Diabetes Metab. 4(4), e00284 (2021). https://doi.org/10.1002/edm2.284
Article CAS PubMed PubMed Central Google Scholar
C. Verdelli, I. Forno, V. Vaira, S. Corbetta, MicroRNA deregulation in parathyroid tumours suggests an embryonic signature. J. Endocrinol. Investig. 38(4), 383–388 (2015). https://doi.org/10.1007/s40618-014-0234-y
A. Morotti, I. Forno, C. Verdelli, V. Guarnieri, F. Cetani, A. Terrasi, R. Silipigni, S. Guerneri, V. Andrè, A. Scillitani, L. Vicentini, S. Ferrero, S. Corbetta, V. Vaira, The oncosuppressors MEN1 and CDC73 are involved in lncRNA deregulation in human parathyroid tumors. J. Bone Miner. Res 35(12), 2423–2431 (2020). https://doi.org/10.1002/jbmr.4154
留言 (0)