Natural autoimmunity in oligoarticular juvenile idiopathic arthritis

Holodick NE, Rodríguez-Zhurbenko N, Hernández AM. Defining natural antibodies. Front Immunol. 2017;8:872.

Article  PubMed  PubMed Central  Google Scholar 

Baumgarth N, Herman OC, Jager GC, Brown L, Herzenberg LA. Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system. Proc Natl Acad Sci USA. 1999;96:2250–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gronwall C, Vas J, Silverman GJ. Protective roles of natural IgM antibodies. Front Immunol. 2012;3:66.

Article  PubMed  PubMed Central  Google Scholar 

Nguyen TT, Elsner RA, Baumgarth N. Natural IgM prevents autoimmunity by enforcing B cell central tolerance induction. J Immunol. 2015;194:1489–502.

Article  CAS  PubMed  Google Scholar 

Nguyen TT, Klasener K, Zurn C, Castillo PA, Brust-Mascher I, Imai DM, et al. The IgM receptor FcmuR limits tonic BCR signaling by regulating expression of the IgM BCR. Nat Immunol. 2017;18:321–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Freitas AA, Viale AC, Sundblad A, Heusser C, Coutinho A. Normal serum immunoglobulins participate in the selection of peripheral B-cell repertoires. Proc Natl Acad Sci USA. 1991;88:5640–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boes M, Esau C, Fischer MB, Schmidt T, Carroll M, Chen J. Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM. J Immunol. 1998;160:4776–87.

Article  CAS  PubMed  Google Scholar 

Nguyen TT, Baumgarth N. Natural IgM and the development of B cell-mediated autoimmune diseases. Crit Rev Immunol. 2016;36:163–77.

Article  PubMed  PubMed Central  Google Scholar 

Notley CA, Brown MA, Wright GP, Ehrenstein MR. Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells. J Immunol. 2011;186:4967–72.

Article  CAS  PubMed  Google Scholar 

Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International League of associations for rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol. 2004;31:390–2.

PubMed  Google Scholar 

Giancane G, Alongi A, Ravelli A. Update on the pathogenesis and treatment of juvenile idiopathic arthritis. Curr Opin Rheumatol. 2017;29:523–9.

Article  CAS  PubMed  Google Scholar 

Leong JY, Guan YJ, Albani S, Arkachaisri T. Recent advances in our understanding of the pathogenesis of juvenile idiopathic arthritis and their potential clinical implications. Expert Rev Clin Immunol. 2018;14:933–44.

Article  CAS  PubMed  Google Scholar 

Corcione A, Ferlito F, Gattorno M, Gregorio A, Pistorio A, Gastaldi R, Gambini C, Martini A, Traggiai E, Pistoia V. Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis. Arthritis Res Ther. 2009;11(5):R150.

Article  PubMed  PubMed Central  Google Scholar 

Wouters CH, Ceuppens JL, Stevens EA. Different circulating lymphocyte profiles in patients with different subtypes of juvenile idiopathic arthritis. Clin Exp Rheumatol. 2002;20(2):239–48.

CAS  PubMed  Google Scholar 

Lee J, Kuchen S, Fischer R, Chang S, Lipsky PE. Identification and characterization of a human CD5+ pre-naive B cell population. J Immunol. 2009;182:4116–26.

Article  CAS  PubMed  Google Scholar 

Wouters CH, Ceuppens JL, Stevens EA. Different circulating lymphocyte profiles in patients with different subtypes of juvenile idiopathic arthritis. Clin Exp Rheumatol. 2002;20:239–48.

CAS  PubMed  Google Scholar 

Corcione A, Ferlito F, Gattorno M, Gregorio A, Pistorio A, Gastaldi R, et al. Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis. Arthritis Res Ther. 2009;11:R150.

Article  PubMed  PubMed Central  Google Scholar 

Sims GP, Ettinger R, Shirota Y, Yarboro CH, Illei GG, Lipsky PE. Identification and characterization of circulating human transitional B cells. Blood. 2005;105:4390–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dighiero G, Guilbert B, Fermand JP, Lymberi P, Danon F, Avrameas S. Thirty-six human monoclonal immunoglobulins with antibody activity against cytoskeleton proteins, thyroglobulin and native DNA: Immunological studies and clinical correlations. Blood. 1983;62:264–70.

Article  CAS  PubMed  Google Scholar 

Zamanou A, Samiotaki M, Panayotou G, Margaritis L, Lymberi P. Fine specificity and subclass of IgG anti-actin autoantibodies differ in health and disease. J Autoimmun. 2003;20:333–44.

Article  CAS  PubMed  Google Scholar 

Brezski RJ, Knight DM, Jordan RE. The origins, specificity, and potential biological relevance of human anti-IgG hinge autoantibodies. ScientificWorldJournal. 2011;11:1153–67.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Welschof M, Terness P, Kipriyanov SM, Stanescu D, Breitling F, Dörsam H, et al. The antigen-binding domain of a human IgG-anti-F(ab’)2 autoantibody. Proc Natl Acad Sci USA. 1997;94:1902–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Terness P, Navolan D, Dufter C, Welschof M, Opelz G. Immunosuppressive anti-immunoglobulin autoantibodies: specificity, gene structure and function in health and disease. Cell Mol Biol. 2002;48:271–8.

CAS  PubMed  Google Scholar 

Consolaro A, Ruperto N, Bazso A, Pistorio A, Magni-Manzoni S, Filocamo G, et al. Development and validation of a composite disease activity score for juvenile idiopathic arthritis. Arthritis Rheum. 2009;61(5):658–66.

Article  PubMed  Google Scholar 

Consolaro A, Ravelli A. Defining criteria for disease activity states in juvenile idiopathic arthritis. Rheumatology. 2016;55(4):595–6.

Article  PubMed  Google Scholar 

Clarke SL, Sen ES, Ramanan AV. Juvenile idiopathic arthritis-associated uveitis. Pediatr Rheumatol Online J. 2016;14(1):27.

Article  PubMed  PubMed Central  Google Scholar 

Dighiero G, Lymberi P, Holmberg D, Lundquist I, Coutinho A, Avrameas S. High frequency of natural autoantibodies in normal newborn mice. J Immunol. 1985;134:765–71.

Article  CAS  PubMed  Google Scholar 

Sali AD, Karakasiliotis I, Evangelidou M, Avrameas S, Lymberi P. Immunological evidence and regulatory potential for cell-penetrating antibodies in intravenous immunoglobulin. Clin Transl Immunol. 2015;4: e42.

Article  Google Scholar 

Nagele EP, Han M, Acharya NK, DeMarshall C, Kosciuk MC, Nagele RG. Natural IgG autoantibodies are abundant and ubiquitous in human sera, and their number is influenced by age, gender, and disease. PLoS ONE. 2013;8(4): e60726.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nguyen TT, Baumgarth N. Natural IgM and the development of b cell-mediated autoimmune diseases. Crit Rev Immunol. 2016;36(2):163–77.

Article  PubMed  PubMed Central  Google Scholar 

McMahon M, Skaggs B. Autoimmunity: Do IgM antibodies protect against atherosclerosis in SLE? Nat Rev Rheumatol. 2016;12(8):442–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang C, Zhao ML, Scearce RM, Diaz M. Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis. Arthritis Rheum. 2011;63(4):1086–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lymberi P, Zannikou M, Hatzioannou A. Natural Autoantibodies in Health and Disease. In Comprehensive Pharmacology. Vol. 5. Elsevier. 2022. p. 342–68. https://doi.org/10.1016/B978-0-12-820472-6.00197-3.

Ragimbeau J, Avrameas S. Single lipopolysaccharide-reactive B cells in the non-immune mouse spleen cell population secrete natural multispecific autoantibodies. Scand J Immunol. 1987;26:29–35.

Article  CAS  PubMed  Google Scholar 

Zhang H, Chen F, Zhao F, Meng C-M. Structural and electronic properties of 2,4,6-trinitrophenol (TNP). J Mol Struct: THEOCHEM. 2008;857:33–7.

Article  CAS  Google Scholar 

Mouthon L, Haury M, Lacroix-Desmazes S, Barreau C, Coutinho A, Kazatchkine MD. Analysis of the normal human IgG antibody repertoire. Evidence that IgG autoantibodies of healthy adults recognize a limited and conserved set of protein antigens in homologous tissues. J Immunol. 1995;154:5769–78.

Article  CAS  PubMed  Google Scholar 

Silvestris F, Bankhurst AD, Searles RP, Williams RC Jr. Studies of anti-F(ab’)2 antibodies and possible immunologic control mechanisms in systemic lupus erythematosus. Arthritis Rheum. 1984;27(12):1387–96.

Article  CAS  PubMed 

留言 (0)

沒有登入
gif