Uncovering a neurological protein signature for severe COVID-19

Keywords

Severe COVID-19

Neurological complications

Olink proteomics

Protein signature

AbbreviationsACVRL1

Activin A Receptor Like Type 1

ARDS

Acute Respiratory Distress Syndrome

COVID-19

Coronavirus Disease 2019

CNS

Central Nervous System

DEPs

Differentially Expressed Proteins

DKK4

Dickkopf WNT Signaling Pathway Inhibitor 4

GDNFR3

GDNF Family Receptor alpha-3

GDNF

Glial Derived Neurotrophic Factor

GFAP

Glial Fibrillary Acidic Protein

IPA

Ingenuity Pathway Analysis

KEGG

Kyoto Encyclopedia of Genes and Genomes

LGI1

Leucine Rich Glioma Inactivated 1

MGH

Massachusetts General Hospital

NEFL

Neurofilament Light Chain

NfL

Neurofilament Light Chain Protein

NPX

Normalized Protein eXpression

PNS

Peripheral Nervous System

PCA

Principal Component Analysis

PHOSPHO1

Phosphoethanolamine/Phosphocholine Phosphatase 1

RGMB

Repulsive Guidance Molecule BMP Co-Receptor B

SARS-CoV-2

Severe Acute Respiratory Syndrome Coronavirus 2

SIGLEC1

Sialic acid-binding ImmunoGlobulin-type Lectins 1

THOP1

Thimet Oligopeptidase 1

TDGF1

Teratocarcinoma-Derived Growth Factor 1

UCH-L1

Ubiquitin Carboxyl-terminal Hydrolase L1

WGCNA

Weighted Gene Co-expression Network Analysis

Data availability

Data will be made available on request.

© 2023 The Author(s). Published by Elsevier Inc.

留言 (0)

沒有登入
gif