Eur Rev Med Pharmacol Sci 2023; 27 (9): 3833-3836

DOI: 10.26355/eurrev_202305_32288

F. Su, X.-X. Meng, C.-Z. Su, J.-L. Zhang

Department of Hepatology, Hebei Traditional Chinese Medicine Hospital, Shijiazhuang, China. zhangjl56@163.com

BACKGROUND: Voriconazole is a new generation of broad-spectrum antifungal agents commonly used in the treatment of invasive aspergillus infections.

CASE REPORT: We reported a rare case of myopathy induced by voriconazole, which showed severe muscle pain and significantly elevated myocardial enzymes. Enzymes eventually achieved good efficacy by switching voriconazole to micafungin and the use of L-carnitine.

CONCLUSIONS: This reminded us it was necessary to be vigilant for rare adverse reactions of voriconazole in the population with liver dysfunction, the elderly population, and people with multiple underlying diseases in clinical practice. During medication of voriconazole, close attention should be paid to the occurrence of adverse reactions to avoid life-threatening complications.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License

F. Su, X.-X. Meng, C.-Z. Su, J.-L. Zhang
A case of drug-induced myopathy in alcoholic cirrhosis caused by voriconazole

Eur Rev Med Pharmacol Sci
Year: 2023
Vol. 27 - N. 9
Pages: 3833-3836
DOI: 10.26355/eurrev_202305_32288