Tsao CW, Aday AW, Almarzooq ZI, Alonso A, Beaton AZ, Bittencourt MS, et al. Heart disease and stroke statistics-2022 update: a report from the American Heart Association. Circulation. 2022;145:e153–e639.
GBD 2019 Stroke Collaborators Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021;20:795–820.
Bartoli F, Lillia N, Lax A, Crocamo C, Mantero V, Carrà G, et al. Depression after stroke and risk of mortality: a systematic review and meta-analysis. Stroke Res Treat. 2013;2013:862978.
PubMed PubMed Central Google Scholar
The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581–7.
Kutlubaev MA, Hackett ML, Part II. predictors of depression after stroke and impact of depression on stroke outcome: an updated systematic review of observational studies. Int J Stroke. 2014;9:1026–36.
Towfighi A, Ovbiagele B, El Husseini N, Hackett ML, Jorge RE, Kissela BM, et al. Poststroke depression: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2017;48:e30–e43.
Hackett ML, Pickles K, Part I. frequency of depression after stroke: an updated systematic review and meta-analysis of observational studies. Int J Stroke. 2014;9:1017–25.
Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Health-related quality of life among young adults with ischemic stroke on long-term follow-up. Stroke. 2006;37:1232–6.
Starkstein SE, Robinson RG, Price TR. Comparison of patients with and without poststroke major depression matched for size and location of lesion. Arch Gen Psychiatry. 1988;45:247–52.
Article CAS PubMed Google Scholar
Robinson RG, Jorge RE. Post-stroke depression: a review. Am J Psychiatry. 2016;173:221–31.
Januar V, Ancelin ML, Ritchie K, Saffery R, Ryan J. BDNF promoter methylation and genetic variation in late-life depression. Transl Psychiatry. 2015;5:e619.
Article CAS PubMed PubMed Central Google Scholar
Morris-Blanco KC, Chokkalla AK, Bertogliat MJ, Vemuganti R. TET3 regulates DNA hydroxymethylation of neuroprotective genes following focal ischemia. J Cereb Blood Flow Metab. 2021;41:590–603.
Article CAS PubMed Google Scholar
Jang HS, Shin WJ, Lee JE, Do JT. CpG and non-CpG methylation in epigenetic gene regulation and brain function. Genes. 2017;8:148.
Chokkalla AK, Mehta SL, Vemuganti R. Epitranscriptomic regulation by m(6)A RNA methylation in brain development and diseases. J Cereb Blood Flow Metab. 2020;40:2331–49.
Article CAS PubMed PubMed Central Google Scholar
Buckley NJ, Johnson R, Zuccato C, Bithell A, Cattaneo E. The role of REST in transcriptional and epigenetic dysregulation in Huntington’s disease. Neurobiol Dis. 2010;39:28–39.
Article CAS PubMed Google Scholar
Flamand MN, Meyer KD. The epitranscriptome and synaptic plasticity. Curr Opin Neurobiol. 2019;59:41–8.
Article CAS PubMed PubMed Central Google Scholar
Dauncey MJ. Nutrition, the brain and cognitive decline: insights from epigenetics. Eur J Clin Nutr. 2014;68:1179–85.
Article CAS PubMed Google Scholar
Stankiewicz AM, Swiergiel AH, Lisowski P. Epigenetics of stress adaptations in the brain. Brain Res Bull. 2013;98:76–92.
Article CAS PubMed Google Scholar
Weber-Stadlbauer U. Epigenetic and transgenerational mechanisms in infection-mediated neurodevelopmental disorders. Transl Psychiatry. 2017;7:e1113.
Article CAS PubMed PubMed Central Google Scholar
Allison J, Kaliszewska A, Uceda S, Reiriz M, Arias N. Targeting DNA methylation in the adult brain through diet. Nutrients. 2021;13:3979.
Mosca P, Leheup B, Dreumont N. Nutrigenomics and RNA methylation: Role of micronutrients. Biochimie. 2019;164:53–9.
Article CAS PubMed Google Scholar
Yoon KJ, Ming GL, Song H. Epitranscriptomes in the adult mammalian brain: dynamic changes regulate behavior. Neuron. 2018;99:243–5.
Article CAS PubMed PubMed Central Google Scholar
Morais LH, Schreiber HLT, Mazmanian SK. The gut microbiota-brain axis in behaviour and brain disorders. Nat Rev Microbiol. 2021;19:241–55.
Article CAS PubMed Google Scholar
Jabs S, Biton A, Bécavin C, Nahori MA, Ghozlane A, Pagliuso A, et al. Impact of the gut microbiota on the m(6)A epitranscriptome of mouse cecum and liver. Nat Commun. 2020;11:1344.
Article CAS PubMed PubMed Central Google Scholar
Thomas SP, Denu JM. Short-chain fatty acids activate acetyltransferase p300. eLife. 2021;10:e72171.
Coutinho-Wolino KS, de F Cardozo LFM, de Oliveira Leal V, Mafra D, Stockler-Pinto MB. Can diet modulate trimethylamine N-oxide (TMAO) production? What do we know so far? Eur J Nutr. 2021;60:3567–84.
Article CAS PubMed Google Scholar
Romano KA, Martinez-Del Campo A, Kasahara K, Chittim CL, Vivas EI, Amador-Noguez D, et al. Metabolic, epigenetic, and transgenerational effects of gut bacterial choline consumption. Cell Host Microbe. 2017;22:279–.e277.
Article CAS PubMed PubMed Central Google Scholar
Hashimoto K. Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Psychiatry Clin Neurosci. 2010;64:341–57.
Article CAS PubMed Google Scholar
Zhang E, Liao P. Brain-derived neurotrophic factor and post-stroke depression. J Neurosci Res. 2020;98:537–48.
Article CAS PubMed Google Scholar
Li J, Zhao YD, Zeng JW, Chen XY, Wang RD, Cheng SY. Serum Brain-derived neurotrophic factor levels in post-stroke depression. J Affect Disord. 2014;168:373–9.
Article CAS PubMed Google Scholar
Jin H-J, Pei L, Li Y-N, Zheng H, Yang S, Wan Y, et al. Alleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression. Sci Rep. 2017;7:14926.
Article PubMed PubMed Central Google Scholar
Bernstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell. 2007;128:669–81.
Article CAS PubMed Google Scholar
Xie S, Qian C. The growing complexity of UHRF1-mediated maintenance DNA methylation. Genes. 2018;9:600.
Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, et al. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proc Natl Acad Sci USA. 2014;111:1361–6.
Article CAS PubMed PubMed Central Google Scholar
Szwagierczak A, Bultmann S, Schmidt CS, Spada F, Leonhardt H. Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA. Nucleic Acids Res. 2010;38:e181.
Article PubMed PubMed Central Google Scholar
Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O’Keeffe S, et al. An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci. 2014;34:11929–47.
Article CAS PubMed PubMed Central Google Scholar
Moore LD, Le T, Fan G. DNA methylation and its basic function. Neuropsychopharmacology. 2013;38:23–38.
Article CAS PubMed Google Scholar
Martínez-Iglesias O, Carrera I, Carril JC, Fernández-Novoa L, Cacabelos N, Cacabelos R. DNA methylation in neurodegenerative and cerebrovascular disorders. Int J Mol Sci. 2020;21:2220.
Peña CJ, Nestler EJ. Progress in epigenetics of depression. Prog Mol Biol Transl Sci. 2018;157:41–66.
Article PubMed PubMed Central Google Scholar
Bannister AJ, Kouzarides T. Regulation of chromatin by histone modifications. Cell Res. 2011;21:381–95.
Article CAS PubMed PubMed Central Google Scholar
Dieker J, Muller S. Epigenetic histone code and autoimmunity. Clin Rev Allergy Immunol. 2010;39:78–84.
Article CAS PubMed Google Scholar
Greer EL, Shi Y. Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet. 2012;13:343–57.
留言 (0)