Characterization of elements, PAHs, AhR-activity and pro-inflammatory responses of road tunnel-derived particulate matter in human hepatocyte-like and bronchial epithelial cells

Keywords

Air pollution

Diesel exhaust particles

Inflammation

Metals

Polyaromatic compounds

Aryl hydrocarbon receptor (AhR)

Airway epithelial cells

AbbreviationsAryl hydrocarbon receptor

AhR

chemokine CXC-motif ligand 8

CXCL8

chronic obstructive pulmonary disease

COPD

cytochrome P450 1A1

CYP1A1

dioxin response elements

DREs

diesel exhaust particles

DEP

neutral aromatic fractions

parent and alkylated PAHs, E1

semi-polar aromatic fraction

mononitrated-PAHs, E2

polar aromatic fractions

oxy-PAHs, E3

human bronchial epithelial cells

HBEC3-KT

N-acetyl salicylic acid

NAC

polycyclic aromatic hydrocarbons

PAHs

PM-extractable organic material

EOM

reactive oxygen species

ROS

residual particles after the extractions

PM-EOM

standard error of mean

SEM

2,3,7,8-tetrachlorodibenzo-p-dioxin

TCDD

Data availability

Data will be made available on request.

© 2023 The Authors. Published by Elsevier Ltd.

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