Mayeux R (2004) Biomarkers: potential uses and limitations. NeuroRx 1(2):182–188. https://doi.org/10.1602/neurorx.1.2.182
Article PubMed PubMed Central Google Scholar
Mohapatra D, Jena S, Prusty SK et al (2020) Biomarkers of Alzheimer’s Disease: a review. Sys Rev Pharm. https://doi.org/10.31838/srp.2020.6.24
Jeromin A, Bowser R (2017) Biomarkers in neurodegenerative diseases. Adv Neurobiol 15:491–528. https://doi.org/10.1007/978-3-319-57193-5_20
Rachakonda V, Pan TH, Le WD (2004) Biomarkers of neurodegenerative disorders: how good are they? Cell Res 14(5):347–358. https://doi.org/10.1038/sj.cr.7290235
Article CAS PubMed Google Scholar
Ravnik-Glavač M, Glavač D (2020) Circulating RNAs as potential biomarkers in amyotrophic lateral sclerosis. Int J Mol Sci 21(5):1714. https://doi.org/10.3390/ijms21051714
Article CAS PubMed PubMed Central Google Scholar
Kang J, Kim JW, Heo H et al (2021) Identification of BAG2 and cathepsin D as plasma biomarkers for Parkinson’s Disease. Clin Transl Sci 14(2):606–616. https://doi.org/10.1111/cts.12920
Article CAS PubMed Google Scholar
García-Gutiérrez MS, Navarrete F, Sala F et al (2020) Biomarkers in psy-chiatry: concept, definition, types and relevance to the clinical reality. Front Psychiatry 11:432. https://doi.org/10.3389/fpsyt.2020.00432
Article PubMed PubMed Central Google Scholar
Dhama K, Latheef SK, Dadar M et al (2019) Biomarkers in stress related diseases/disorders: di-agnostic, prognostic, and therapeutic values. Front Mol Biosci 6:91. https://doi.org/10.3389/fmolb.2019.00091
Article CAS PubMed PubMed Central Google Scholar
Califf RM (2018) Biomarker definitions and their applications. Exp Biol Med 243(3):213–221. https://doi.org/10.1177/1535370217750088
Henry NL, Hayes DF (2012) Cancer biomarkers. Mol Oncol 6(2):140–146. https://doi.org/10.1016/j.molonc.2012.01.010
Article CAS PubMed PubMed Central Google Scholar
Cova I, Priori A (2018) Diagnostic biomarkers for Parkinson’s disease at a glance: where are we? J Neural Transm 125(10):1417–1432. https://doi.org/10.1007/s00702-018-1910-4
Article CAS PubMed Google Scholar
Chen JJ, Lu TP, Chen YC (2015) Predictive biomarkers for treatment selection: statistical considerations. Biomark Med 9(11):1121–1135. https://doi.org/10.2217/bmm.15.84
Article CAS PubMed Google Scholar
Hampel H, Blennow K (2004) CSF tau and β-amyloid as biomarkers for mild cognitive impairment. Dialogues Clin Neurosci 6(4):379–390. https://doi.org/10.31887/DCNS.2004.6.4/hhampel
Article PubMed PubMed Central Google Scholar
Kany S, Vollrath JT, Relja B (2019) Cytokines in inflammatory disease. Int J Mol Sci 20(23):6008. https://doi.org/10.3390/ijms20236008
Article CAS PubMed PubMed Central Google Scholar
Tanaka T, Narazaki M, Kishimoto T (2014) IL-6 in inflammation, immunity, and disease. Cold Spring Harb Perspect Biol 6(10):a016295. https://doi.org/10.1101/cshperspect.a016295
Article PubMed PubMed Central Google Scholar
Ntetsika T, Papathoma PE, Markaki I (2021) Novel targeted therapies for Parkinson’s disease. Mol Med 27(1):17. https://doi.org/10.1186/s10020-021-00279-2
Article CAS PubMed PubMed Central Google Scholar
Kon T, Tomiyama M, Wakabayashi K (2020) Neuropathology of Lewy body disease: Clinicopathological crosstalk be-tween typical and atypical cases. Neuropathology 40(1):30–39. https://doi.org/10.1111/neup.12597
Article CAS PubMed Google Scholar
Reeve AK, Grady JP, Cosgrave EM et al (2018) Mitochondrial dys-function within the synapses of substantia nigra neurons in Parkinson’s disease. NPJ Parkinsons Dis 4(1):1–10. https://doi.org/10.1038/s41531-018-0044-6
Le W, Dong J, Li S et al (2017) Can biomarkers help the early diagnosis of parkinson’s disease? Neurosci Bull 33(5):535–542. https://doi.org/10.1007/s12264-017-0174-6
Article CAS PubMed PubMed Central Google Scholar
Fagan AM, Holtzman DM (2010) Cerebrospinal fluid biomarkers of Alzheimer’s disease. Biomark Med 4(1):51–63. https://doi.org/10.2217/BMM.09.83
Article CAS PubMed Google Scholar
Buddhala C, Campbell MC, Perlmutter JS, Kotzbauer PT (2015) Correlation between decreased CSF α-synuclein and Aβ1–42 in Parkinson disease. Neurobiol Aging 36(1):476–484. https://doi.org/10.1016/j.neurobiolaging.2014.07.043
Article CAS PubMed Google Scholar
Mita Y, Kataoka Y, Saito Y et al (2018) Distribution of oxidized DJ-1 in Parkinson’s disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin. Sci Rep 8(1):12056. https://doi.org/10.1038/s41598-018-30561-z
Article CAS PubMed PubMed Central Google Scholar
He R, Yan X, Guo J et al (2018) Recent advances in biomarkers for parkinson’s disease. Front Aging Neurosci 10:305. https://doi.org/10.3389/fnagi.2018.00305
Article CAS PubMed PubMed Central Google Scholar
Sathe G, Na CH, Renuse S et al (2019) Quantitative proteomic profil-ing of cerebrospinal fluid to identify candidate biomarkers for alzheimer’s disease. Proteomics Clin Appl 13(4):e1800105. https://doi.org/10.1002/prca.201800105
Article CAS PubMed Google Scholar
Gómez-Benito M, Granado N, García-Sanz P et al (2020) Modeling Parkinson’s Disease With the Alpha-Synuclein Protein. Front Pharmacol 11:356. https://doi.org/10.3389/fphar.2020.00356
Article CAS PubMed PubMed Central Google Scholar
Wakabayashi K, Tanji K, Mori F et al (2007) The Lewy body in Parkinson’s disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates. Neuropathology 27(5):494–506. https://doi.org/10.1111/j.1440-1789.2007.00803.x
Yang HJ, Vainshtein A, Maik-Rachline G et al (2016) G protein-coupled receptor 37 is a negative regulator of oli-godendrocyte differentiation and myelination. Nat Commun 7:10884. https://doi.org/10.1038/ncomms10884
Article CAS PubMed PubMed Central Google Scholar
Liu B, Mosienko V, Vaccari Cardoso B (2018) Glio- and neuro-protection by prosaposin is mediated by orphan G-protein coupled receptors GPR37L1 and GPR37. Glia 66(11):2414–2426. https://doi.org/10.1002/glia.23480
Article PubMed PubMed Central Google Scholar
Hebron ML, Lonskaya I, Sharpe K et al (2013) Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6). J Bio Chem 288(6):4103–4115. https://doi.org/10.1074/jbc.M112.419945
Marazziti D, Golini E, Mandillo S et al (2004) Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson’s disease-associated GPR37/parkin-associated endo-thelin-like receptor. Proc Nat Acad Sci USA 101(27):10189–10194. https://doi.org/10.1073/pnas.0403661101
Article CAS PubMed PubMed Central Google Scholar
Morató X, Garcia-Esparcia P, Argerich J et al (2021) Ecto-GPR37: a potential biomarker for Parkinson’s dis-ease. Transl Neurodegener 10(1):8. https://doi.org/10.1186/s40035-021-00232-7
Article CAS PubMed PubMed Central Google Scholar
Berti V, Pupi A, Mosconi L (2011) PET/CT in diagnosis of movement disorders. Ann NY Acad Sci 1228:93–108. https://doi.org/10.1111/j.1749-6632.2011.06025.x
Article CAS PubMed Google Scholar
Yeshokumar AK, Saylor D, Kornberg MD et al (2015) Evidence for the importance of vitamin D status in neu-rologic conditions. Curr Treat Options Neurol 17(12):51. https://doi.org/10.1007/s11940-015-0380-3
Malek N, Lawton MA, Swallow DM et al (2016) Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson’s disease. Mov Disord 31(10):1518–1526. https://doi.org/10.1002/mds.26698
Article CAS PubMed PubMed Central Google Scholar
Ascherio A, LeWitt PA, Xu K et al (2009) Urate as a predictor of the rate of clinical decline in Parkinson disease. Arch Neurol 66(12):1460–1468. https://doi.org/10.1001/archneurol.2009.247
Article PubMed PubMed Central Google Scholar
Lawton M, Baig F, Toulson G, Morovat A, Evetts SG, Ben-Shlomo Y, Hu MT (2020) Blood biomarkers with Parkin-son’s disease clusters and prognosis: The oxford discovery cohort. Mov Disord 35(2):279–287. https://doi.org/10.1002/mds.27888
留言 (0)