Linear accelerator-based stereotactic radiotherapy for brain metastases, including multiple and large lesions, carries a low incidence of acute toxicities: a retrospective analysis

Yamamoto M, Serizawa T, Shuto T, Akabane A, Higuchi Y, Kawagishi J, et al. Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study. Lancet Oncol. 2014;15:387–95.

Article  PubMed  Google Scholar 

Kondziolka D, Patel A, Lunsford LD, Kassam A, Flickinger JC. Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases. Int J Radiat Oncol Biol Phys. 1999;45:427–34.

Article  CAS  PubMed  Google Scholar 

Smart D. Radiation toxicity in the central nervous system: mechanisms and strategies for injury reduction. Semin Radiat Oncol. 2017;27:332–9.

Article  PubMed  PubMed Central  Google Scholar 

Milano MT, Grimm J, Niemierko A, Soltys SG, Moiseenko V, Redmond KJ, et al. Single- and multifraction stereotactic radiosurgery dose/volume tolerances of the brain. Int J Radiat Oncol Biol Phys. 2021;110:68–86.

Article  PubMed  Google Scholar 

Blonigen BJ, Steinmetz RD, Levin L, Lamba MA, Warnick RE, Breneman JC. Irradiated volume as a predictor of brain radionecrosis after linear accelerator stereotactic radiosurgery. Int J Radiat Oncol Biol Phys. 2010;77:996–1001.

Article  PubMed  Google Scholar 

Sneed PK, Mendez J, Vemer-van den Hoek JGM, Seymour ZA, Ma L, Molinaro AM, et al. Adverse radiation effect after stereotactic radiosurgery for brain metastases: incidence, time course, and risk factors. J Neurosurg. 2015;123:373–86.

Lehrer EJ, Peterson JL, Zaorsky NG, Brown PD, Sahgal A, Chiang VL, et al. Single versus multifraction stereotactic radiosurgery for large brain metastases: an international meta-analysis of 24 trials. Int J Radiat Oncol Biol Phys. 2019;103:618–30.

Article  PubMed  Google Scholar 

Werner-Wasik M, Rudoler S, Preston PE, Hauck WW, Downes BM, Leeper D, et al. Immediate side effects of stereotactic radiotherapy and radiosurgery. Int J Radiat Oncol Biol Phys. 1999;43:299–304.

Article  CAS  PubMed  Google Scholar 

Arvold ND, Pinnell NE, Mahadevan A, Connelly S, Silverman R, Weiss SE, et al. Steroid and anticonvulsant prophylaxis for stereotactic radiosurgery: large variation in physician recommendations. Pract Radiat Oncol. 2016;6:e89-96.

Article  PubMed  Google Scholar 

Alongi F, Fiorentino A, Gregucci F, Corradini S, Giaj-Levra N, Romano L, et al. First experience and clinical results using a new non-coplanar mono-isocenter technique (HyperArc™) for Linac-based VMAT radiosurgery in brain metastases. J Cancer Res Clin Oncol. 2019;145:193–200.

Article  CAS  PubMed  Google Scholar 

Minniti G, Capone L, Nardiello B, El Gawhary R, Raza G, Scaringi C, et al. Neurological outcome and memory performance in patients with 10 or more brain metastases treated with a frameless linear accelerator (LINAC)-based stereotactic radiosurgery. J Neurooncol. 2020;148:47–55.

Article  PubMed  Google Scholar 

Minniti G, Scaringi C, Paolini S, Lanzetta G, Romano A, Cicone F, et al. Single-fraction versus multifraction (3 × 9 Gy) stereotactic radiosurgery for large (>2 cm) brain metastases: a comparative analysis of local control and risk of radiation-induced brain necrosis. Int J Radiat Oncol Biol Phys. 2016;95:1142–8.

Article  PubMed  Google Scholar 

Kanayama N, Ikawa T, Ohira S, Hirata T, Morimoto M, Ogawa K, et al. Volumetric reduction of brain metastases after stereotactic radiotherapy: prognostic factors and effect on local control. Cancer Med. 2022;11:4806–15.

Article  PubMed  PubMed Central  Google Scholar 

Ohira S, Ueda Y, Kanayama N, Isono M, Inui S, Komiyama R, et al. Impact of multileaf collimator width on dose distribution in HyperArc fractionated stereotactic irradiation for multiple (-) brain metastases. Anticancer Res. 2021;41:3153–9.

Article  PubMed  Google Scholar 

Komiyama R, Ohira S, Ueda H, Kanayama N, Masaoka A, Isono M, et al. Intra-fractional patient motion when using the Qfix Encompass immobilization system during HyperArc treatment of patients with brain metastases. J Appl Clin Med Phys. 2021;22:254–60.

Article  PubMed  PubMed Central  Google Scholar 

George EJS, Kudhail J, Perks J, Plowman PN. Acute symptoms after gamma knife radiosurgery. J Neurosurg. 2002;97:631–4.

Article  Google Scholar 

Tokuuye K, Akine Y, Sumi M, Kagami Y, Murayama S, Nakayama H, et al. Fractionated stereotactic radiotherapy of small intracranial malignancies. Int J Radiat Oncol Biol Phys. 1998;42:989–94.

Article  CAS  PubMed  Google Scholar 

Ernst-Stecken A, Ganslandt O, Lambrecht U, Sauer R, Grabenbauer G. Phase II trial of hypofractionated stereotactic radiotherapy for brain metastases: results and toxicity. Radiother Oncol. 2006;81:18–24.

Article  PubMed  Google Scholar 

Manning MA, Cardinale RM, Benedict SH, Kavanagh BD, Zwicker RD, Amir C, et al. Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of patients with brain metastases. Int J Radiat Oncol Biol Phys. 2000;47:603–8.

Article  CAS  PubMed  Google Scholar 

Aoyama H, Shirato H, Onimaru R, Kagei K, Ikeda J, Ishii N, et al. Hypofractionated stereotactic radiotherapy alone without whole-brain irradiation for patients with solitary and oligo brain metastasis using noninvasive fixation of the skull. Int J Radiat Oncol Biol Phys. 2003;56:793–800.

Article  PubMed  Google Scholar 

Lutterbach J, Cyron D, Henne K, Ostertag CB. Radiosurgery followed by planned observation in patients with one to three brain metastases. Neurosurgery. 2003;52:1066–74.

PubMed  Google Scholar 

Williams BJ, Suki D, Fox BD, Pelloski CE, Maldaun MVC, Sawaya RE, et al. Stereotactic radiosurgery for metastatic brain tumors: a comprehensive review of complications. J Neurosurg. 2009;111:439–48.

Article  PubMed  Google Scholar 

Nath SK, Lawson JD, Simpson DR, Vanderspek L, Wang J-Z, Alksne JF, et al. Single-isocenter frameless intensity-modulated stereotactic radiosurgery for simultaneous treatment of multiple brain metastases: clinical experience. Int J Radiat Oncol Biol Phys. 2010;78:91–7.

Article  PubMed  Google Scholar 

Aoyama H, Shirato H, Tago M, Nakagawa K, Toyoda T, Hatano K, et al. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA. 2006;295:2483–91.

Article  CAS  PubMed  Google Scholar 

Rajakesari S, Arvold ND, Jimenez RB, Christianson LW, Horvath MC, Claus EB, et al. Local control after fractionated stereotactic radiation therapy for brain metastases. J Neurooncol. 2014;120:339–46.

Article  CAS  PubMed  Google Scholar 

Jimenez RB, Alexander BM, Mahadevan A, Niemierko A, Rajakesari S, Arvold ND, et al. The impact of different stereotactic radiation therapy regimens for brain metastases on local control and toxicity. Adv Radiat Oncol. 2017;2:391–7.

Article  PubMed  PubMed Central  Google Scholar 

de la Pinta C, Fernández-Lizarbe E, Sevillano D, Capúz AB, Martín M, Hernanz R, et al. Brain metastases: single-dose radiosurgery versus hypofractionated stereotactic radiotherapy: a retrospective study. J Clin Transl Res. 2020;6:6–13.

PubMed  PubMed Central  Google Scholar 

Lerner EC, Srinivasan ES, Broadwater G, Haskell-Mendoza AP, Edwards RM, Huie D, et al. Factors associated with new-onset seizures following stereotactic radiosurgery for newly diagnosed brain metastases. Adv Radiat Oncol. 2022;7: 101054.

Article  PubMed  PubMed Central  Google Scholar 

Nei M, Bagla R. Seizure-related injury and death. Curr Neurol Neurosci Rep. 2007;7:335–41.

Article  PubMed  Google Scholar 

Murayi R, Chittiboina P. Glucocorticoids in the management of peritumoral brain edema: a review of molecular mechanisms. Childs Nerv Syst. 2016;32:2293–302.

Article  PubMed  PubMed Central  Google Scholar 

Kaal ECA, Vecht CJ. The management of brain edema in brain tumors. Curr Opin Oncol. 2004;16:593–600.

Article  CAS  PubMed  Google Scholar 

Berkman RA, Merrill MJ, Reinhold WC, Monacci WT, Saxena A, Clark WC, et al. Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms. J Clin Invest. 1993;91:153–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park JS, Qiao L, Su ZZ, Hinman D, Willoughby K, McKinstry R, et al. Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways. Oncogene. 2001;20:3266–80.

Article  CAS  PubMed  Google Scholar 

Hanna A, Boggs DH, Kwok Y, Simard M, Regine WF, Mehta M. What predicts early volumetric edema increase following stereotactic radiosurgery for brain metastases? J Neurooncol. 2016;127:303–11.

Article  PubMed  Google Scholar 

Dietrich J, Rao K, Pastorino S, Kesari S. Corticosteroids in brain cancer patients: benefits and pitfalls. Expert Rev Clin Pharmacol. 2011;4:233–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arbour KC, Mezquita L, Long N, Rizvi H, Auclin E, Ni A, et al. Impact of baseline steroids on efficacy of programmed cell death-1 and programmed death-ligand 1 blockade in patients with non-small-cell lung cancer. J Clin Oncol. 2018;36:2872–8.

Article  CAS  PubMed  Google Scholar 

Fokas E, Henzel M, Surber G, Kleinert G, Hamm K, Engenhart-Cabillic R. Stereotactic radiosurgery and fractionated stereotactic radiotherapy: comparison of efficacy and toxicity in 260 patients with brain metastases. J Neurooncol. 2012;109:91–8.

Article  PubMed  Google Scholar 

Loghin M, Levin VA. Headache related to brain tumors. Curr Treat Options Neurol. 2006;8:21–32.

留言 (0)

沒有登入
gif