Abravanel F, Nicot F, Lhomme S, Cazabat M, Drumel T, Velay A, Latour J, Belliere J, Cintas P, Kamar N, Izopet J (2021) Hepatitis E virus quasispecies in cerebrospinal fluid with neurological manifestations. Vaccines (Basel) 9(10):1205. https://doi.org/10.3390/vaccines9101205

Article  CAS  PubMed  Google Scholar 

Abravanel F, Pique J, Couturier E, Nicot F, Dimeglio C, Lhomme S, Chiabrando J, Saune K, Péron JM, Kamar N, Evrard S, de Valk H, Cintas P, Izopet J, HEV study group (2018) Acute hepatitis E in French patients and neurological manifestations. J Infect 77(3):220–226. https://doi.org/10.1016/j.jinf.2018.06.007

Article  PubMed  Google Scholar 

Chen XD, Zhou YT, Zhou JJ, Wang YW, Tong DM (2014) Guillain-Barré syndrome and encephalitis/encephalopathy of a rare case of Northern China acute severe hepatitis E infection. Neurol Sci 35(9):1461–1463. https://doi.org/10.1007/s10072-014-1731-7

Article  PubMed  Google Scholar 

Dalton HR, van Eijk JJJ, Cintas P, Madden RG, Jones C, Webb GW, Norton B, Pique J, Lutgens S, Devooght-Johnson N, Woolson K, Baker J, Saunders M, Househam L, Griffiths J, Abravanel F, Izopet J, Kamar N, van Alfen N, van Engelen BGM, Hunter JG, van der Eijk AA, Bendall RP, Mclean BN, Jacobs BC (2017) Hepatitis E virus infection and acute non-traumatic neurological injury: a prospective multicentre study. J Hepatol 67(5):925–932. https://doi.org/10.1016/j.jhep.2017.07.010

Article  PubMed  Google Scholar 

de Vries MA, Samijn JP, de Man R, Boots JM (2014) Hepatitis E-associated encephalopathy in a renal transplant recipient. BMJ Case Rep. https://doi.org/10.1136/bcr-2014-204244

Deroux A, Brion JP, Hyerle L, Belbezier A, Vaillant M, Mosnier E, Larrat S, Morand P, Pavese P (2014) Association between hepatitis E and neurological disorders: two case studies and literature review. J Clin Virol 60(1):60–62. https://doi.org/10.1016/j.jcv.2014.01.026

Article  CAS  PubMed  Google Scholar 

Despierres LA, Kaphan E, Attarian S, Cohen-Bacrie S, Pelletier J, Pouget J, Motte A, Charrel R, Gerolami R (2010) Colson P (2011) Neurologic disorders and hepatitis E, France. Emerg Infect Dis 17(8):1510–1512. https://doi.org/10.3201/eid1708.102028

Article  Google Scholar 

Gynthersen RMM, Rønn CP, Brandt CT, Mens H (2020) Severe acute hepatitis E infection presenting with acute abdomen and meningoencephalitis. BMJ Case Rep 13(12):e236922. https://doi.org/10.1136/bcr-2020-236922

Kamar N, Bendall RP, Peron JM, Cintas P, Prudhomme L, Mansuy JM, Rostaing L, Keane F, Ijaz S, Izopet J, Dalton HR (2011) Hepatitis E virus and neurologic disorders. Emerg Infect Dis 17(2):173–179. https://doi.org/10.3201/eid1702.100856

Article  PubMed  PubMed Central  Google Scholar 

Kamar N, Marion O, Abravanel F, Izopet J, Dalton HR (2016) Extrahepatic manifestations of hepatitis E virus. Liver Int 36(4):467–472. https://doi.org/10.1111/liv.13037

Article  PubMed  Google Scholar 

Kejariwal D, Roy S, Sarkar N (2001) Seizure associated with acute hepatitis E. Neurology 57(10):1935. https://doi.org/10.1212/wnl.57.10.1935

Article  CAS  PubMed  Google Scholar 

Lhomme S, Abravanel F, Cintas P, Izopet J (2021) Hepatitis E virus infection: neurological manifestations and pathophysiology. Pathogens 10(12):1582. https://doi.org/10.3390/pathogens10121582

Article  CAS  PubMed  PubMed Central  Google Scholar 

Murkey JA, Chew KW, Carlson M, Shannon CL, Sirohi D, Sample HA, Wilson MR, Vespa P, Humphries RM, Miller S, Klausner JD, Chiu CY (2017) Hepatitis E virus-associated meningoencephalitis in a lung transplant recipient diagnosed by clinical metagenomic sequencing. Open Forum Infect Dis 4(3):ofx121. https://doi.org/10.1093/ofid/ofx121

Nimgaonkar I, Ding Q, Schwartz RE, Ploss A (2018) Hepatitis E virus: advances and challenges. Nat Rev Gastroenterol Hepatol 15(2):96–110. https://doi.org/10.1038/nrgastro.2017.150

Article  PubMed  Google Scholar 

Pasha SA, Pasha SA, Suhasini T, Rao DA (2018) Hepatitis E virus-associated acute encephalitic parkinsonism. J Assoc Physicians India 66(3):92–93

PubMed  Google Scholar 

Salim OJ, Davidson A, Li K, Leach JP, Heath C (2017) Brainstem encephalitis and acute polyneuropathy associated with hepatitis E infection. BMJ Case Rep. https://doi.org/10.1136/bcr-2017-220799

Stahl JP, Azouvi P, Bruneel F, De Broucker T, Duval X, Fantin B, Girard N, Herrmann JL, Honnorat J, Lecuit M, Mailles A, Martinez-Almoyna L, Morand P, Piroth L, Tattevin P, reviewing group, (2017) Guidelines on the management of infectious encephalitis in adults. Med Mal Infect 47(3):179–194. https://doi.org/10.1016/j.medmal.2017.01.005

Article  CAS  PubMed  Google Scholar 

Tian J, Shi R, Liu T, She R, Wu Q, An J, Hao W, Soomro MH (2019) Brain infection by hepatitis E virus probably via damage of the blood-brain barrier due to alterations of tight junction proteins. Front Cell Infect Microbiol 9:52. https://doi.org/10.3389/fcimb.2019.00052

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wallace SJ, Swann R, Donnelly M, Kemp L, Guaci J, Murray A, Spoor J, Lin N, Miller M, Dalton HR, Hussaini SH, Gunson R, Simpson K, Stanley A, Fraser A (2020) Mortality and morbidity of locally acquired hepatitis E in the national Scottish cohort: a multicentre retrospective study. Aliment Pharmacol Ther 51(10):974–986. https://doi.org/10.1111/apt.15704

Article  PubMed  Google Scholar 

Zhou X, Huang F, Xu L, Lin Z, de Vrij FMS, Ayo-Martin AC, van der Kroeg M, Zhao M, Yin Y, Wang W, Cao W, Wang Y, Kushner SA, Marie Peron J, Alric L, de Man RA, Jacobs BC, van Eijk JJ, Aronica EMA, Sprengers D, Metselaar HJ, de Zeeuw CI, Dalton HR, Kamar N, Peppelenbosch MP, Pan Q (2017) Hepatitis E virus infects neurons and brains. J Infect Dis 215(8):1197–1206. https://doi.org/10.1093/infdis/jix079

Article  CAS  PubMed  Google Scholar