Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006;38:904–9.
Article CAS PubMed Google Scholar
Bycroft C, Freeman C, Petkova D, Band G, Elliott LT, Sharp K, et al. The UK Biobank resource with deep phenotyping and genomic data. Nature. 2018;562:203–9.
Article CAS PubMed PubMed Central Google Scholar
Naret O, Kutalik Z, Hodel F, Xu ZM, Marques-Vidal P, Fellay J. Improving polygenic prediction with genetically inferred ancestry. HGG Adv. 2022;3:100109.
CAS PubMed PubMed Central Google Scholar
Agrawal A, Chiu AM, Le M, Halperin E, Sankararaman S, Gravel S. Scalable probabilistic PCA for large-scale genetic variation data. PLoS Genet. 2020;16:e1008773.
Article CAS PubMed PubMed Central Google Scholar
Reed E, Nunez S, Kulp D, Qian J, Reilly MP, Foulkes AS. A guide to genome-wide association analysis and post-analytic interrogation. Stat Med. 2015;34:3769–92.
Article PubMed PubMed Central Google Scholar
Clifton L, Collister JA, Liu X, Littlejohns TJ, Hunter DJ. Assessing agreement between different polygenic risk scores in the UK Biobank. Sci Rep. 2022;12:12812.
Article CAS PubMed PubMed Central Google Scholar
Tanigawa Y, Qian J, Venkataraman G, Justesen JM, Li R, Tibshirani R, et al. Significant sparse polygenic risk scores across 813 traits in UK Biobank. PLoS Genet. 2022;18:e1010105.
Article CAS PubMed PubMed Central Google Scholar
Yun J-S, Jung SH, Shivakumar M, Xiao B, Khera AV, Won HH, et al. Polygenic risk for type 2 diabetes, lifestyle, metabolic health, and cardiovascular disease: a prospective UK Biobank study. Cardiovasc Diabetol. 2022;21:131.
Article CAS PubMed PubMed Central Google Scholar
Prive F, Aschard H, Carmi S, Folkersen L, Hoggart C, O’Reilly PF, et al. Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort. Am J Hum Genet. 2022;109:12–23.
Article CAS PubMed PubMed Central Google Scholar
Ge T, Irvin MR, Patki A, Srinivasasainagendra V, Lin YF, Tiwari HK, et al. Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. Genome Med. 2022;14:70.
Article PubMed PubMed Central Google Scholar
Elliott LT, Sharp K, Alfaro-Almagro F, Shi S, Miller KL, Douaud G, et al. Genome-wide association studies of brain imaging phenotypes in UK Biobank. Nature. 2018;562:210–6.
Article CAS PubMed PubMed Central Google Scholar
Hellwege JN, Keaton JM, Giri A, Gao X, Velez Edwards DR, Edwards TL. Population stratification in genetic association studies. Curr Protoc Hum Genet. 2017;95:520.
Price AL, Zaitlen NA, Reich D, Patterson N. New approaches to population stratification in genome-wide association studies. Nat Rev Genet. 2010;11:459–63.
Article CAS PubMed PubMed Central Google Scholar
Pirastu N, Cordioli M, Nandakumar P, Mignogna G, Abdellaoui A, Hollis B, et al. Genetic analyses identify widespread sex-differential participation bias. Nat Genet. 2021;53:663–71.
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