Whey protein hydrolysates improve high-fat-diet-induced obesity by modulating the brain–peripheral axis of GLP-1 through inhibition of DPP-4 function in mice

Miralpeix C, Reguera AC, Fosch A et al (2021) Hypothalamic endocannabinoids in obesity: an old story with new challenges. Cell Mol Life Sci 78(23):7469–7490. https://doi.org/10.1007/s00018-021-04002-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

van Bloemendaal L, ten Kulve JS, La Fleur SE et al (2014) Effects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS. J Endocrinol 221(1):T1-16. https://doi.org/10.1530/JOE-13-0414

Article  CAS  PubMed  Google Scholar 

Schroeder LE, Leinninger GM (2018) Role of central neurotensin in regulating feeding: Implications for the development and treatment of body weight disorders. Biochim Biophys Acta—Mol Basis Dis 1864(3):900–916. https://doi.org/10.1016/j.bbadis.2017.12.036

Bauer PV, Hamr SC, Duca FA (2016) Regulation of energy balance by a gut-brain axis and involvement of the gut microbiota. Cell Mol Life Sci 73(4):737–755. https://doi.org/10.1007/s00018-015-2083-z

Article  CAS  PubMed  Google Scholar 

Batterham RL, Cowley MA, Small CJ et al (2002) Gut hormone PYY(3–36) physiologically inhibits food intake. Nature 418:650–654. https://doi.org/10.1038/NATURE00887

Article  CAS  PubMed  Google Scholar 

Holst JJ (1994) Glucagonlike peptide 1: a newly discovered gastrointestinal hormone. Gastroenterology 107(6):1848–1855. https://doi.org/10.1016/0016-5085(94)90831-1

Article  CAS  PubMed  Google Scholar 

Drucker DJ (1998) Perspectives in diabetes: glucagon-like peptides. Diabetes 47(2):159–169. https://doi.org/10.2337/diab.47.2.159

Article  CAS  PubMed  Google Scholar 

Farooqui AA, Farooqui T, Panza F, Frisardi V (2012) Metabolic syndrome as a risk factor for neurological disorders. Cell Mol Life Sci 69(5):741–762. https://doi.org/10.1007/s00018-011-0840-1

Article  CAS  PubMed  Google Scholar 

Tsang AH, Nuzzaci D, Darwish T et al (2020) Nutrient sensing in the nucleus of the solitary tract mediates non-aversive suppression of feeding via inhibition of AgRP neurons. Mol Metab 42:101070. https://doi.org/10.1016/j.molmet.2020.101070

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brierley DI, Holt MK, Singh A et al (2021) Central and peripheral GLP-1 systems independently suppress eating. Nat Metab 3:258–273. https://doi.org/10.1038/s42255-021-00344-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dakin CL, Gunn I, Small CJ et al (2001) Oxyntomodulin inhibits food intake in the rat. Endocrinology 142:4244–4250. https://doi.org/10.1210/ENDO.142.10.8430

Article  CAS  PubMed  Google Scholar 

Panjwani N, Mulvihill EE, Longuet C et al (2013) GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE −/− mice. Endocrinology 154(1):127–139. https://doi.org/10.1210/en.2012-1937

Article  CAS  PubMed  Google Scholar 

Le Roux CW, Aylwin SJB, Batterham RL et al (2006) Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters. Ann Surg 243:108–114. https://doi.org/10.1097/01.SLA.0000183349.16877.84

Article  PubMed  PubMed Central  Google Scholar 

Lamers D, Famulla S, Wronkowitz N et al (2011) Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes 60:1917–1925. https://doi.org/10.2337/DB10-1707

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wronkowitz N, Görgens SW, Romacho T et al (1842) (2014) Soluble DPP4 induces inflammation and proliferation of human smooth muscle cells via protease-activated receptor 2. Biochim Biophys Acta - Mol Basis Dis 9:1613–1621. https://doi.org/10.1016/j.bbadis.2014.06.004

Article  CAS  Google Scholar 

Chou E, Suzuma I, Way KJ et al (2002) Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue. Circulation 105:373–379. https://doi.org/10.1161/HC0302.102143

Article  CAS  PubMed  Google Scholar 

Yoon YS, Uchida S, Masuo O et al (2005) Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor. Circulation 111:2073–2085. https://doi.org/10.1161/01.CIR.0000162472.52990.36

Article  CAS  PubMed  Google Scholar 

Zhong J, Maiseyeu A, Davis SN, Rajagopalan S (2015) DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition. Circ Res 116(8):1491–1504. https://doi.org/10.1161/CIRCRESAHA.116.305665

Article  CAS  PubMed  PubMed Central  Google Scholar 

Knudsen LB (2019) Inventing liraglutide, a glucagon-like peptide-1 analogue, for the treatment of diabetes and obesity. ACS Pharmacol Transl Sci 2:468–484. https://doi.org/10.1021/ACSPTSCI.9B00048

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gregoire FM, Smas CM, Sul HS (1998) Understanding adipocyte differentiation. Physiol Rev 78(3):783–809. https://doi.org/10.1152/physrev.1998.78.3.783

Article  CAS  PubMed  Google Scholar 

Jakab J, Miškić B, Mikšić Š, et al (2021) Adipogenesis as a potential anti-obesity target: A review of pharmacological treatment and natural products. Diabetes Metab Syndr Obes Targets Ther 14:67–83. https://doi.org/10.2147/DMSO.S281186. (eCollection 2021)

Mauro M, Taylor V, Wharton S, Sharma AM (2008) Barriers to obesity treatment. Eur J Intern Med 19:173–180. https://doi.org/10.1016/J.EJIM.2007.09.011

Article  PubMed  Google Scholar 

Konstantinidi M, Koutelidakis AE (2019) Functional foods and bioactive compounds: a review of its possible role on weight management and obesity’s metabolic consequences. Medicines 6(3):94. https://doi.org/10.3390/medicines6030094

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chuang CC, Martinez K, Xie G et al (2010) Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-α-mediated inflammation and insulin resistance in primary human adipocytes. Am J Clin Nutr 92(6):1511–1521. https://doi.org/10.3945/ajcn.2010.29807

Article  CAS  PubMed  Google Scholar 

van Heerden FR (2008) Hoodia gordonii: a natural appetite suppressant. J Ethnopharmacol 119(3):434–437. https://doi.org/10.1016/j.jep.2008.08.023

Article  PubMed  Google Scholar 

Hall WL, Millward DJ, Long SJ, Morgan LM (2003) Casein and whey exert different effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite. Br J Nutr 89:239–248. https://doi.org/10.1079/BJN2002760

Article  CAS  PubMed  Google Scholar 

Westerterp-Plantenga MS, Nieuwenhuizen A, Tomé D et al (2009) Dietary protein, weight loss, and weight maintenance. Annu Rev Nutr 29:21–41. https://doi.org/10.1146/ANNUREV-NUTR-080508-141056

Article  CAS  PubMed  Google Scholar 

Ewert J, Luz A, Volk V et al (2019) Enzymatic production of emulsifying whey protein hydrolysates without the need of heat inactivation. J Sci Food Agric 99:3443–3450. https://doi.org/10.1002/JSFA.9562

Article  CAS  PubMed  Google Scholar 

Krissansen GW (2007) Emerging health properties of whey proteins and their clinical implications. J Am Coll Nutr 26(6):713S-S723. https://doi.org/10.1080/07315724.2007.10719652

Article  CAS  PubMed  Google Scholar 

Jeewanthi RKC, Kim MH, Lee NK et al (2017) peptide analysis and the bioactivity of whey protein hydrolysates from cheese whey with several enzymes. Korean J food Sci Anim Resour 37:62–70. https://doi.org/10.5851/KOSFA.2017.37.1.62

Article  PubMed  PubMed Central  Google Scholar 

Nongonierma AB, Lalmahomed M, Paolella S, FitzGerald RJ (2017) Milk protein isolate (MPI) as a source of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides. Food Chem 231:202–211. https://doi.org/10.1016/J.FOODCHEM.2017.03.123

Article  CAS  PubMed  Google Scholar 

Bendtsen LQ, Lorenzen JK, Bendsen NT et al (2013) Effect of dairy proteins on appetite, energy expenditure, body weight, and composition: a review of the evidence from controlled clinical trials. Adv Nutr 4(4):418–438. https://doi.org/10.3945/an.113.003723

Article  CAS  PubMed  PubMed Central  Google Scholar 

Walsh DJ, Bernard H, Murray BA et al (2004) In vitro generation and stability of the lactokinin β-lactoglobulin fragment (142–148). J Dairy Sci 87: (11):3845–57. https://doi.org/10.3168/jds.S0022-0302(04)73524-

Article  CAS  PubMed  Google Scholar 

Majid A, Lakshmikanth M, Lokanath NK, Poornima Priyadarshini CG (2022) Generation, characterization and molecular binding mechanism of novel dipeptidyl peptidase-4 inhibitory peptides from sorghum bicolor seed protein. Food Chem 369:130888. https://doi.org/10.1016/j.foodchem.2021.130888

Article  CAS  PubMed  Google Scholar 

Kumar R, Joshi R, Kumari M et al (2020) Elevated CO2 and temperature influence key proteins and metabolites associated with photosynthesis, antioxidant and carbon metabolism in Picrorhiza kurroa. J Proteomics 219:103755. https://doi.org/10.1016/j.jprot.2020.103755

Article  CAS  PubMed  Google Scholar 

Rai C, Nandini CD, Priyadarshini P (2021) Composition and structure elucidation of bovine milk glycosaminoglycans and their anti-adipogenic activity via modulation PPAR-γ and C/EBP-α. Int J Biol Macromol 193(Pt A):137–144. https://doi.org/10.1016/j.ijbiomac.2021.10.076

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