Carlsson SK, Brothers SP, Wahlestedt C (2014) Emerging treatment strategies for glioblastoma multiforme. EMBO Mol Med 6(11):1359–1370. https://doi.org/10.15252/emmm.201302627

Article  CAS  PubMed  PubMed Central  Google Scholar 

da Hora CC, Schweiger MW, Wurdinger T, Tannous BA (2019) Patient-derived glioma models: from patients to dish to animals. Cells 8(10). https://doi.org/10.3390/cells8101177

Davis ME (2016) Glioblastoma: overview of Disease and Treatment.Clin. J Oncol Nurs 20(5 Suppl):S2–8. https://doi.org/10.1188/16.CJON.S1.2-8

Article  Google Scholar 

Di Renzo MF, Corso S (2020) Patient-derived Cancer Models. Cancers (Basel) 12(12). https://doi.org/10.3390/cancers12123779

Li H, Lei B, Xiang W, Wang H, Feng W, Liu Y et al (2017) Differences in protein expression between the U251 and U87 cell Lines.Turk Neurosurg. 27(6):894–903. https://doi.org/10.5137/1019-5149.JTN.17746-16.1

Alexanian AR, Huang YW (2015) Specific combinations of the chromatin-modifying enzyme modulators significantly attenuate glioblastoma cell proliferation and viability while exerting minimal effect on normal adult stem cells growth.Tumour Biol. https://doi.org/10.1007/s13277-015-3654-1

Arthurs AL, Keating DJ, Stringer BW, Conn SJ (2020) The suitability of Glioblastoma Cell Lines as Models for primary glioblastoma cell Metabolism.Cancers (Basel). 12(12). https://doi.org/10.3390/cancers12123722

Ye LF, Reznik E, Korn JM, Lin F, Yang G, Malesky K et al (2020) Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery.Oncotarget.11. 4443–451. https://doi.org/10.18632/oncotarget.27457

Goodspeed A, Heiser LM, Gray JW, Costello JC (2016) Tumor-derived cell lines as Molecular Models of Cancer Pharmacogenomics. Mol Cancer Res 14(1):3–13. https://doi.org/10.1158/1541-7786.MCR-15-0189

Article  CAS  PubMed  Google Scholar 

Sharma SV, Haber DA, Settleman J (2010) Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents. Nat Rev Cancer 10(4):241–253. https://doi.org/10.1038/nrc2820

Article  CAS  PubMed  Google Scholar 

Stringer BW, Day BW, D’Souza RCJ, Jamieson PR, Ensbey KS, Bruce ZC et al (2019) A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma. Sci Rep 9(1):4902. https://doi.org/10.1038/s41598-019-41277-z

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alexanian AR, Brannon A (2022) Unique combinations of epigenetic modifiers synergistically impair the viability of the U87 glioblastoma cell line while exhibiting minor or moderate effects on normal stem cell growth. Med Oncol 39(5):86. https://doi.org/10.1007/s12032-022-01683-2

Article  CAS  PubMed  Google Scholar 

Chaichana KL, Guerrero-Cazares H, Capilla-Gonzalez V, Zamora-Berridi G, Achanta P, Gonzalez-Perez O et al (2009) Intra-operatively obtained human tissue: protocols and techniques for the study of neural stem cells. J Neurosci Methods 180(1):116–125. https://doi.org/10.1016/j.jneumeth.2009.02.014

Article  CAS  PubMed  PubMed Central  Google Scholar 

Binder ZA, Wilson KM, Salmasi V, Orr BA, Eberhart CG, Siu IM et al (2016) Establishment and Biological characterization of a panel of Glioblastoma Multiforme (GBM) and GBM variant Oncosphere Cell Lines. PLoS ONE 11(3):e0150271. https://doi.org/10.1371/journal.pone.0150271

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ying M, Wang S, Sang Y, Sun P, Lal B, Goodwin CR et al (2011) Regulation of glioblastoma stem cells by retinoic acid: role for notch pathway inhibition.Oncogene.30. 313454–3467. https://doi.org/10.1038/onc.2011.58

Li Y, Li A, Glas M, Lal B, Ying M, Sang Y et al (2011) c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proc Natl Acad Sci U S A 108(24):9951–9956. https://doi.org/10.1073/pnas.1016912108

Article  PubMed  PubMed Central  Google Scholar 

Tilghman J, Wu H, Sang Y, Shi X, Guerrero-Cazares H, Quinones-Hinojosa A et al (2014) HMMR maintains the stemness and tumorigenicity of glioblastoma stem-like cells. Cancer Res 74(11):3168–3179. https://doi.org/10.1158/0008-5472.CAN-13-2103

Article  CAS  PubMed  PubMed Central  Google Scholar 

Auvergne R, Wu C, Connell A, Au S, Cornwell A, Osipovitch M et al (2016) PAR1 inhibition suppresses the self-renewal and growth of A2B5-defined glioma progenitor cells and their derived gliomas in vivo.Oncogene.35. 293817–3828. https://doi.org/10.1038/onc.2015.452

Garcia CA, Bhargav AG, Brooks M, Suarez-Meade P, Mondal SK, Zarco N et al (2021) Functional characterization of brain tumor-initiating cells and establishment of GBM Preclinical Models that incorporate heterogeneity, therapy, and sex differences. Mol Cancer Ther 20(12):2585–2597. https://doi.org/10.1158/1535-7163.MCT-20-0547

Article  CAS  PubMed  PubMed Central  Google Scholar