1 Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Pharmacotherapy and Outcome Sciences, Virginia Commonwealth University, Richmond, Virginia, United States
,
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
4 Clinical Trial Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran
5 Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Hooman Bakhshandeh
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
4 Clinical Trial Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Babak Sharif-Kashani
6 Tobacoo Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
7 Department of Cardiology, Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Farid Rashidi
8 Tuberclosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Mohammad Taghi Beigmohammadi
9 Department of Intensive Care, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tehran, Iran
,
Keivan Gohari Moghadam
10 Department of Internal Medicine, School of Medicine, Shariati Hospital, Tehran, Iran
,
Somaye Rezaian
11 Department of Internal Medicine, Alborz University of Medicine Science, Karaj, Iran
,
12 Department of Anesthesiology, School of Medicine Anesthesiology Research Center Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Seyed Hashem Sezavar
13 Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
,
Mohsen Farrokhpour
14 Department of Internal Medicine, Iran University of Medical Sciences, Firouzgar Hospital, Tehran, Iran
,
Atefeh Abedini
15 Chronic Respiratory Disease Research Center, Shahid Beheshti University of Medical Sciences, Masih Daneshvari Hospital, Tehran, Iran
,
Rasoul Aliannejad
16 Department of Pulmonary and Critical Care, School of Medicine, Shariati Hospital, Tehran, Iran
17 Advanced Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran
,
Taghi Riahi
18 Department of Internal Medicine, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Mahdi Yadollahzadeh
14 Department of Internal Medicine, Iran University of Medical Sciences, Firouzgar Hospital, Tehran, Iran
,
Somayeh Lookzadeh
15 Chronic Respiratory Disease Research Center, Shahid Beheshti University of Medical Sciences, Masih Daneshvari Hospital, Tehran, Iran
,
Parisa Rezaeifar
8 Tuberclosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Samira Matin
8 Tuberclosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Ouria Tahamtan
8 Tuberclosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Keyhan Mohammadi
19 Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
,
Elnaz Zoghi
19 Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
,
Hamid Rahmani
19 Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
,
Seyed Hossein Hosseini
19 Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
,
Seyed Masoud Mousavian
18 Department of Internal Medicine, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Homa Abri
14 Department of Internal Medicine, Iran University of Medical Sciences, Firouzgar Hospital, Tehran, Iran
,
Pardis Sadeghipour
14 Department of Internal Medicine, Iran University of Medical Sciences, Firouzgar Hospital, Tehran, Iran
,
Elahe Baghizadeh
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Farnaz Rafiee
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Sepehr Jamalkhani
20 Student Research Committee, Iran University of Medical Sciences, Tehran, Iran
21 Department of Pharmacotherapy, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tehran, Iran
,
Ahmad Amin
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Bahram Mohebbi
5 Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Seyed Ehsan Parhizgar
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Mahshid Soleimanzadeh
12 Department of Anesthesiology, School of Medicine Anesthesiology Research Center Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Maryam Aghakouchakzadeh
19 Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
,
Vahid Eslami
22 Department of Emergency Medicine, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Pooya Payandemehr
23 Department of Emergency Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
,
Hossein Khalili
21 Department of Pharmacotherapy, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tehran, Iran
,
Hamed Talakoob
24 Cardiovascular Research Center, Alborz University of Medical Sciences, Karaj, Iran
,
Taranom Tojari
25 Department of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran
,
Shadi Shafaghi
7 Department of Cardiology, Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Sanaz Tabrizi
18 Department of Internal Medicine, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Hessam Kakavand
19 Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
,
Alireza Kashefizadeh
26 Department of Internal Medicine, Shahid Dr. Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Atabak Najafi
22 Department of Emergency Medicine, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
27 Respiratory Department, Hospital Ramón y Cajal (IRYCIS), Madrid, Spain
28 Medicine Department, Universidad de Alcalá (IRYCIS), Madrid, Spain
29 CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain
,
Aakriti Gupta
30 Yale/YNHH Center for Outcomes Research and Evaluation (CORE), New Haven, Connecticut, United States
31 Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, California, United States
,
Mahesh V. Madhavan
32 Cardiovascular Research Foundation (CRF), New York, New York, United States
33 Division of Cardiology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, New York, United States
,
Sanjum S. Sethi
32 Cardiovascular Research Foundation (CRF), New York, New York, United States
33 Division of Cardiology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, New York, United States
,
Sahil A. Parikh
32 Cardiovascular Research Foundation (CRF), New York, New York, United States
33 Division of Cardiology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, New York, United States
,
34 Cátedra de Enfermedad Tromboembólica, Universidad Católica de Murcia, Murcia, Spain
,
Naser Hadavand
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Alireza Hajighasemi
1 Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
,
Khalil Ansarin
8 Tuberclosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
Majid Maleki
3 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Saeed Sadeghian
1 Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
,
35 Department of Angiology, University Hospital Zurich, Zurich, Switzerland
36 Center for Thrombosis and Hemostasis, Johannes Gutenberg University Mainz, Mainz, Germany
,
Bob Siegerink
37 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
,
Erica S. Spatz
38 Yale/YNHH Center for Outcomes Research and Evaluation, New Haven, Connecticut, United States
39 Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States
,
40 Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
41 Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Ajay J. Kirtane
40 Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
41 Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Benjamin W. Van Tassell
2 Department of Pharmacotherapy and Outcome Sciences, Virginia Commonwealth University, Richmond, Virginia, United States
,
Gregory Y. H. Lip
42 Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom
43 Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
,
44 Department of Medicine - Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, The Netherlands
,
Samuel Z. Goldhaber
40 Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
41 Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Gregg W. Stone
32 Cardiovascular Research Foundation (CRF), New York, New York, United States
45 The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States
,
Harlan M. Krumholz
30 Yale/YNHH Center for Outcomes Research and Evaluation (CORE), New Haven, Connecticut, United States
39 Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States
46 Department of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut, United States
,
Behnood Bikdeli
32 Cardiovascular Research Foundation (CRF), New York, New York, United States
38 Yale/YNHH Center for Outcomes Research and Evaluation, New Haven, Connecticut, United States
40 Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
41 Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
› Author AffiliationsThe study was funded by the Rajaie Cardiovascular Medical and Research Center. Atorvastatin and matching placebo were provided by Sobhan Darou, which is not among the study sponsors. Neither the funder nor the company who donated the study drugs had any role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or the decision to submit the manuscript(s) for publication. Dr. Bikdeli is supported by the Scott Schoen and Nancy Adams IGNITE Award from the Mary Horrigan Connors Center for Women's Health and Gender Biology at Brigham and Women's Hospital and a Career Development Award from the American Heart Association and VIVA Physicians (#938814).
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