Tran, O. N., Wang, H., Dean, D. D., Chen, X.-D. & Yeh, C.-K. Stem cell-based restoration salivary gland function. Chapter 14. In: A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics. X.-D. Chen (editor), Academic Press, pp. 345–366 (2019). https://doi.org/10.1016/b978-0-12-811920-4.00014-8.
Valstar, M. H. et al. The tubarial salivary glands: A potential new organ at risk for radiotherapy. Radiother. Oncol. 154, 292–298 (2021).
Guggenheimer, J. & Moore, P. A. Xerostomia: Etiology, recognition and treatment. J. Am. Dent. Assoc. 134, 61–69 (2003).
Smith, C. H. et al. Effect of aging on stimulated salivary flow in adults. J. Am. Geriatr. Soc. 61, 805–808 (2013).
Tanaka, J. & Mishima, K. Application of regenerative medicine to salivary gland hypofunction. Jpn. Dent. Sci. Rev. 57, 54–59 (2021).
Article PubMed PubMed Central Google Scholar
Martínez-Acitores, L. R. et al. Xerostomia and salivary flow in patients taking antihypertensive drugs. Int. J. Environ. Res Pu 17, 2478 (2020).
Ramírez, L. et al. Risk factors associated with xerostomia and reduced salivary flow in hypertensive patients. Oral Dis. (2021) https://doi.org/10.1111/odi.14090.
Marcott, S. et al. Where dysphagia begins: Polypharmacy and xerostomia. Fed. Pract. Heal Care Prof. Va Dod. Phs 37, 234–241 (2020).
Fernandes, M. S. et al. Relationship between polypharmacy, xerostomia, gustatory sensitivity, and swallowing complaints in the elderly: A multidisciplinary approach. J. Texture Stud. 52, 187–196 (2021).
Ship, J. A., Pillemer, S. R. & Baum, B. J. Xerostomia and the geriatric patient. J. Am. Geriatr. Soc. 50, 535–543 (2002).
Vissink, A., Jansma, J., Spijkervet, F. K. L., Burlage, F. R. & Coppes, R. P. Oral sequelae of head and neck radiotherapy. Crit. Rev. Oral. Biol. Med 14, 199–212 (2003).
Langendijk, J. A. et al. Impact of late treatment-related toxicity on quality of life among patients with head and neck cancer treated with radiotherapy. J. Clin. Oncol. 26, 3770–3776 (2008).
Ho, K. F. et al. Developing a CTCAEs patient questionnaire for late toxicity after head and neck radiotherapy. Eur. J. Cancer 45, 1992–1998 (2009).
Wang, X. Y. et al. Phenylephrine alleviates 131I damage in submandibular gland through promoting endogenous stem cell regeneration via lissencephaly-1 upregulation. Toxicol. Appl Pharm. 396, 114999 (2020).
Tanwar, K. S., Rana, N., Mittal, B. R. & Bhattacharya, A. Early quantification of salivary gland function after radioiodine therapy. Indian J. Nucl. Med. 36, 25–31 (2021).
Article PubMed PubMed Central Google Scholar
Sunavala‐Dossabhoy, G. Radioactive iodine: An unappreciated threat to salivary gland function. Oral. Dis. 24, 198–201 (2018).
Article PubMed PubMed Central Google Scholar
Hesselink, E. N. K. et al. Effects of radioiodine treatment on salivary gland function in patients with differentiated thyroid carcinoma: A prospective study. J. Nucl. Med 57, 1685–1691 (2016).
Mavragani, C. P. Mechanisms and new strategies for primary Sjögren’s Syndrome. Annu Rev. Med. 68, 331–343 (2017).
Brito-Zerón, P. et al. Sjögren syndrome. Nat. Rev. Dis. Prim. 2, 16047 (2016).
Rocchi, C. & Emmerson, E. Mouth-watering results: Clinical need, current approaches, and future directions for salivary gland regeneration. Trends Mol. Med 26, 649–669 (2020).
Weng, P., Luitje, M. E. & Ovitt, C. E. Cellular plasticity in salivary gland regeneration. Oral. Dis. 25, 1837–1839 (2019).
Vivino, F. et al. Sjogren’s syndrome: An update on disease pathogenesis, clinical manifestations, and treatment. Clin. Immunol. 203, 81–121 (2019).
Moutsopoulos, H. M. Sjögren’s syndrome: autoimmune epithelitis. Clin. Immunol. Immunop 72, 162–165 (1994).
Sandhya, P., Kurien, B., Danda, D. & Scofield, R. Update on pathogenesis of Sjogren’s Syndrome. Curr. Rheumatol. Rev. 13, 5–22 (2017).
Article PubMed PubMed Central Google Scholar
Lindahl, G., Hedfors, E., Klareskog, L. & Forsum, U. Epithelial HLA-DR expression and T lymphocyte subsets in salivary glands in Sjögren’s syndrome. Clin. Exp. Immunol. 61, 475–482 (1985).
PubMed PubMed Central Google Scholar
Moutsopoulos, H. M. et al. HLA-DR expression by labial minor salivary gland tissues in Sjögren’s syndrome. Ann. Rheum. Dis. 45, 677 (1986).
Article PubMed PubMed Central Google Scholar
Xanthou, G. et al. “Lymphoid” chemokine messenger RNA expression by epithelial cells in the chronic inflammatory lesion of the salivary glands of Sjögren’s syndrome patients: Possible participation in lymphoid structure formation. Arthritis Rheumatism 44, 408–418 (2001).
Ogawa, N., Ping, L., Zhenjun, L., Takada, Y. & Sugai, S. Involvement of the interferon‐γ–induced T cell–attracting chemokines, interferon‐γ–inducible 10‐kd protein (CXCL10) and monokine induced by interferon‐γ (CXCL9), in the salivary gland lesions of patients with Sjögren’s syndrome. Arthritis Rheumatism 46, 2730–2741 (2002).
Jin, J.-O., Shinohara, Y. & Yu, Q. Innate immune signaling induces interleukin-7 production from salivary gland cells and accelerates the development of primary Sjӧgren’s Syndrome in a mouse model. Plos One 8, e77605 (2013).
Article PubMed PubMed Central Google Scholar
Ciccia, F. et al. Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren’s syndrome. Ann. Rheum. Dis. 71, 295 (2012).
Cha, S. et al. A dual role for interferon‐γ in the pathogenesis of Sjögren’s Syndrome‐like autoimmune exocrinopathy in the nonobese diabetic mouse. Scand. J. Immunol. 60, 552–565 (2004).
Pérez, P. et al. Increased acinar damage of salivary glands of patients with Sjögren’s syndrome is paralleled by simultaneous imbalance of matrix metalloproteinase 3/tissue inhibitor of metalloproteinases 1 and matrix metalloproteinase 9/tissue inhibitor of metalloproteinases 1 ratios. Arthritis Rheumatism 52, 2751–2760 (2005).
Asatsuma, M. et al. Increase in the ratio of matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 in saliva from patients with primary Sjögren’s syndrome. Clin. Chim. Acta 345, 99–104 (2004).
Rosignoli, F. et al. Defective signalling in salivary glands precedes the autoimmune response in the non‐obese diabetic mouse model of sialadenitis. Clin. Exp. Immunol. 142, 411–418 (2005).
Article PubMed PubMed Central Google Scholar
Cha, S. et al. Abnormal organogenesis in salivary gland development may initiate adult onset of autoimmune exocrinopathy. Exp. Clin. Immunogenet 18, 143–160 (2001).
Kiripolsky, J. et al. Immune-intrinsic Myd88 directs the production of antibodies with specificity for extracellular matrix components in primary Sjögren’s syndrome. Front Immunol. 12, 692216 (2021).
Article PubMed PubMed Central Google Scholar
Rocchi, C., Barazzuol, L. & Coppes, R. P. The evolving definition of salivary gland stem cells. Npj Regen. Med. 6, 4 (2021).
Article PubMed PubMed Central Google Scholar
Nagler, R. M. The enigmatic mechanism of irradiation-induced damage to the major salivary glands. Oral. Dis. 8, 141–146 (2002).
Radfar, L. & Sirois, D. A. Structural and functional injury in minipig salivary glands following fractionated exposure to 70 Gy of ionizing radiation: an animal model for human radiation-induced salivary gland injury. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endodontol. 96, 267–274 (2003).
Teshima, K. et al. Radiation-induced parotid gland changes in oral cancer patients: Correlation between parotid volume and saliva production. Jpn. J. Clin. Oncol. 40, 42–46 (2010).
Wang, Z. et al. Radiation‐induced volume changes in parotid and submandibular glands in patients with head and neck cancer receiving postoperative radiotherapy: A longitudinal study. Laryngoscope 119, 1966–1974 (2009).
Cheng, S. C. H., Wu, V. W. C., Kwong, D. L. W. & Ying, M. T. C. Assessment of post-radiotherapy salivary glands. Br. J. Radiol. 84, 393–402 (2011).
Article PubMed PubMed Central Google Scholar
Wu, V. W. C. & Leung, K. Y. A review on the assessment of radiation induced salivary gland damage after radiotherapy. Front. Oncol. 9, 1090 (2019).
留言 (0)