Fibroblast growth factor 2 reduces endoplasmic reticulum stress and apoptosis in in-vitro Non-Alcoholic Fatty Liver Disease model

Caldwell SH, et al. Mitochondrial abnormalities in non-alcoholic steatohepatitis. J Hepatol. 1999;31(3):430–4. https://doi.org/10.1016/S0168-8278(99)80033-6\.

Article  CAS  PubMed  Google Scholar 

Povsic M, et al. A structured literature review of the epidemiology and disease burden of non-alcoholic steatohepatitis (NASH). Adv ther. 2019;36(7):1574–94. https://doi.org/10.1007/s12325-019-00960-3.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Uygun A, et al. Metformin in the treatment of patients with non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2004;19(5):537–44. https://doi.org/10.1111/j.1365-2036.2004.01888.x.

Article  CAS  PubMed  Google Scholar 

Younossi ZM. The epidemiology of nonalcoholic steatohepatitis. Clin Liver Dis. 2018;11(4):92–4. https://doi.org/10.1002/cld.710.

Article  Google Scholar 

Zhang X-Q, et al. Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease. World J Gastroenterol: WJG. 2014;20(7):1768. https://doi.org/10.3748/wjg.v20.i7.1768.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lebeaupin C, et al. Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease. J Hepatol. 2018;69(4):927–47. https://doi.org/10.1016/j.jhep.2018.06.008.

Article  CAS  PubMed  Google Scholar 

Kuo TF, et al. Free fatty acids induce transglutaminase 2-dependent apoptosis in hepatocytes via ER stress-stimulated PERK pathways. J Cell Physiol. 2012;227(3):1130–7. https://doi.org/10.1002/jcp.22833.

Article  CAS  PubMed  Google Scholar 

Ajoolabady A, et al. Endoplasmic reticulum stress in liver diseases. Hepatology. 2022;77(2):619–39. https://doi.org/10.1002/hep.32562.

Article  CAS  PubMed  Google Scholar 

Zhang Y, et al. Role of ER Stress in Xenobiotic-Induced Liver Diseases and Hepatotoxicity. Oxidative Med Cell Longev. 2022;2022:4640161. https://doi.org/10.1155/2022/4640161.

Article  CAS  Google Scholar 

Lee S, et al. Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease. Oncotarget. 2017;8(38):63370. https://doi.org/10.18632/oncotarget.18812.

Article  PubMed  PubMed Central  Google Scholar 

Bandla H, et al. Deletion of endoplasmic reticulum stress-responsive co-chaperone p58IPK protects mice from diet-induced steatohepatitis. Hepatol Res. 2018;48(6):479–94. https://doi.org/10.1111/hepr.13052.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liang X-Y, Hong F-F, Yang S-L. Astragaloside IV Alleviates Liver Inflammation, Oxidative Stress and Apoptosis to Protect Against Experimental Non-Alcoholic Fatty Liver Disease. Diabetes Metab Syndr Obes: Targets Ther. 2021;14:1871. https://doi.org/10.2147/DMSO.S304817.

Article  Google Scholar 

Tan X, et al. Fibroblast growth factor 2 attenuates renal ischemia-reperfusion injury via inhibition of endoplasmic reticulum stress. Front Cell Dev Biol. 2020;8:147. https://doi.org/10.3389/fcell.2020.00147.

Article  PubMed  PubMed Central  Google Scholar 

Sun D, et al. bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats. Cell Death Dis. 2018;9(2):1–14. https://doi.org/10.1038/s41419-017-0229-7.

Article  CAS  Google Scholar 

Akl MR, et al. Molecular and clinical significance of fibroblast growth factor 2 (FGF2/bFGF) in malignancies of solid and hematological cancers for personalized therapies. Oncotarget. 2016;7(28):44735. https://doi.org/10.18632/oncotarget.8203.

Article  PubMed  PubMed Central  Google Scholar 

Luo P, Liu H. Basic fibroblast growth factor improves cellular immunological functions in mice. J Sci Innov Res. 2014;3(1):5–10.

Article  Google Scholar 

Frautschy SA, Walicke PA, Baird A. Localization of basic fibroblast growth factor and its mRNA after CNS injury. Brain Res. 1991;553(2):291–9. https://doi.org/10.1016/0006-8993(91)90837-L.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rabchevsky A, et al. Basic fibroblast growth factor (bFGF) enhances functional recovery following severe spinal cord injury to the rat. Exp Neurol. 2000;164(2):280–91. https://doi.org/10.1006/exnr.2000.7399.

Article  CAS  PubMed  Google Scholar 

Pan RL, et al. Low-molecular-weight fibroblast growth factor 2 attenuates hepatic fibrosis by epigenetic down-regulation of Delta-like1. Hepatology. 2015;61(5):1708–20. https://doi.org/10.1002/hep.27649.

Article  CAS  PubMed  Google Scholar 

Kurniawan DW, et al. Fibroblast growth factor 2 conjugated superparamagnetic iron oxide nanoparticles (FGF2-SPIONs) ameliorate hepatic stellate cells activation in vitro and acute liver injury in vivo. J Control Release. 2020;328:640–52. https://doi.org/10.1016/j.jconrel.2020.09.041.

Article  CAS  PubMed  Google Scholar 

Shatta MA. et al., Rhamnetin ameliorates non-alcoholic steatosis and hepatocellular carcinoma in vitro. Mol Cell Biochem, 2022;2022:1–16 https://doi.org/10.1007/s11010-022-04619-6.

Yu H-H, et al. Exendin-4 Attenuates Hepatic Steatosis by Promoting the Autophagy-Lysosomal Pathway. BioMed Res Int. 2022;2022:4246086. https://doi.org/10.1155/2022/4246086.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang H, et al. FTZ attenuates liver steatosis and fibrosis in the minipigs with type 2 diabetes by regulating the AMPK signaling pathway. Biomed Pharmacother. 2021;138:111532. https://doi.org/10.1016/j.biopha.2021.111532.

Article  CAS  PubMed  Google Scholar 

Müller FA, Sturla SJ. Human in vitro models of nonalcoholic fatty liver disease. Curr Opin Toxicol. 2019;16:9–16. https://doi.org/10.1016/j.cotox.2019.03.001.

Article  Google Scholar 

Moravcova A, et al. The effect of oleic and palmitic acid on induction of steatosis and cytotoxicity on rat hepatocytes in primary culture. Physiol Res. 2015;64(Suppl 5):S627-36.

Article  CAS  PubMed  Google Scholar 

Cui W, Chen SL, Hu K-Q. Quantification and mechanisms of oleic acid-induced steatosis in HepG2 cells. Am J Transl Res. 2010;2(1):95.

CAS  PubMed  PubMed Central  Google Scholar 

Wu R, et al. Transcriptional and post-transcriptional control of autophagy and adipogenesis by YBX1. Cell Death Dis. 2023;14(1):29. https://doi.org/10.1038/s41419-023-05564-y.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gulzar F, et al. NOD1 activation in 3T3-L1 adipocytes confers lipid accumulation in HepG2 cells. Life Sci. 2023;316:121400. https://doi.org/10.1016/j.lfs.2023.121400.

Article  CAS  PubMed  Google Scholar 

Nawrocka D, et al. Basic fibroblast growth factor inhibits apoptosis and promotes proliferation of adipose-derived mesenchymal stromal cells isolated from patients with type 2 diabetes by reducing cellular oxidative stress. Oxidative Med Cell Longev. 2017;2017:302. https://doi.org/10.1155/2017/3027109.

Article  CAS  Google Scholar 

Riboni L, Tettamanti G, Viani P. Ceramide in primary astrocytes from cerebellum: metabolism and role in cell proliferation. Cerebellum. 2002;1(2):129–35. https://doi.org/10.1080/147342202753671268.

Article  CAS  PubMed  Google Scholar 

Wang Z-G, et al. bFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway. Sci Rep. 2015;5(1):1–12. https://doi.org/10.1038/srep09287.

Article  CAS  Google Scholar 

Kıvılcım T, et al. Role of bacteriological agents in idiopathic granulomatous mastitis: real or not? Eur J Breast Health. 2019;15(1):32. https://doi.org/10.5152/ejbh.2018.4249.

Article  PubMed  Google Scholar 

Zhang HY, et al. Exogenous basic fibroblast growth factor inhibits ER stress–induced apoptosis and improves recovery from spinal cord injury. CNS Neurosci Ther. 2013;19(1):20–9. https://doi.org/10.1111/cns.12013.

Article  CAS  PubMed  Google Scholar 

Wang Z, et al. bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI 3K/Akt/ERK 1/2 pathway. J Cell Mol Med. 2015;19(3):595–607. https://doi.org/10.1111/jcmm.12346.

Article  CAS  PubMed  Google Scholar 

Gehrmann W, et al. Antagonism between saturated and unsaturated fatty acids in ROS mediated lipotoxicity in rat insulin-producing cells. Cell Physiol Biochem. 2015;36(3):852–65. https://doi.org/10.1159/000430261.

Article  CAS  PubMed  Google Scholar 

Lin Z, et al. Intranasal basic fibroblast growth factor attenuates endoplasmic reticulum stress and brain injury in neonatal hypoxic-ischaemic injury. Am J Transl Res. 2017;9(2):275.

CAS  PubMed  PubMed Central  Google Scholar 

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