1Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

aCorresponding author Edouard L. Fu Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women’s Hospital 1620 Tremont St., BC-3030, Boston, MA 02120 E-mail: [email protected], Phone: (617) 318-8143