From the ∗Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

†Hubei Province Key Laboratory of Molecular Imaging

‡Key Laboratory of Biological Targeted Therapy, the Ministry of Education

§Departments of Neurology, Union Hospital, Medical College, Huazhong University of Science and Technology, Wuhan, China

Received for publication November 25, 2022; revision accepted March 3, 2023.

Conflicts of interest and sources of funding: This work was supported by the National Natural Science Foundation of China (no. 81701759 and 81901735) and the Key Project of Hubei Province Technical Innovation (2017ACA182). All authors declare that they have no conflict of interest.

Authorship Contributions: X.L. and X.S. conceived and designed the study; W.R. acquired the PET/MRI and provided technique support; Y.G. and Q.L. synthesized probes; Y.S. and Z.L. provided the clinical information and made the diagnosis; X.X. collected and conducted the statistical analysis; F.L. contributed in the reviewed the data; X.X. wrote the manuscript; and X.L. and X.S. reviewed and revised the manuscript. All the authors reviewed and approved the final version of the article.

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Correspondence to: Xiaoli Lan, MD, PhD, Jiefang Ave 1277, Wuhan, Hubei Province 430022, China. E-mail: [email protected]; Xun Sun, MD, PhD, Jiefang Ave 1277, Wuhan, Hubei Province 430022, China. E-mail: [email protected].