Motor-kognitives Risikosyndrom – Weichenstellung für die Demenzprävention?

Allali G, Ayers EI, Verghese J (2016) Motoric cognitive risk syndrome subtypes and cognitive profiles. J Gerontol A Biol Sci Med Sci 71(3):378–384

Article  PubMed  Google Scholar 

Ayers E, Verghese J (2014) Diagnosing motoric cognitive risk syndrome to predict progression to dementia. Neurodegener Dis Manag 4(5):339–342

Article  PubMed  Google Scholar 

Ayers E, Wang C, Verghese J (2022) Validation of a “subjective motoric cognitive risk syndrome” screening tool for motoric cognitive risk syndrome—a prospective cohort study. Eur J Neurol. https://doi.org/10.1111/ene.15476

Article  PubMed  PubMed Central  Google Scholar 

Beauchet O, Allali G, Annweiler C et al (2016) Association of motoric cognitive risk syndrome with brain volumes: results from the GAIT study. J Gerontol A Biol Sci Med Sci 71(8):1081–1088

Article  PubMed  Google Scholar 

Beauchet O, Annweiler C, Callisaya ML et al (2016) Poor gait performance and prediction of dementia: results from a meta-analysis. J Am Med Dir Assoc 17(6):482–490

Article  PubMed  PubMed Central  Google Scholar 

Beauchet O, Sekhon H, Schott A‑M et al (2019) Motoric cognitive risk syndrome and risk for falls, their recurrence, and postfall fractures: results from a prospective observational population-based cohort study. J Am Med Dir Assoc 20(10):1268–1273

Article  PubMed  Google Scholar 

Beauchet O, Sekhon H, Cooper-Brown L et al (2021) Motoric cognitive risk syndrome and incident dementia in older adults from the Québec NuAge cohort. Age Ageing 50(3):969–973

Article  PubMed  Google Scholar 

Beauchet O, Sekhon H, Launay CP et al (2021) Pre-dementia stages and incident dementia in the NuAge study. J Alzheimers Dis 80(4):1465–1470

Article  CAS  PubMed  Google Scholar 

Callisaya ML, Ayers E, Barzilai N et al (2016) Motoric cognitive risk syndrome and falls risk: a multi-center study. J Alzheimers Dis 53(3):1043–1052

Article  PubMed  PubMed Central  Google Scholar 

Chhetri JK, Han C, Dan X et al (2020) Association of motoric cognitive risk syndrome with cardiovascular disease and risk factors: results from an original study and meta-analysis. J Am Med Dir Assoc 21(1):136–137

Article  PubMed  Google Scholar 

Creese B, Ismail Z (2022) Mild behavioral impairment: measurement and clinical correlates of a novel marker of preclinical Alzheimer’s disease. Alzheimers Res Ther 14(1):2

Article  CAS  PubMed  PubMed Central  Google Scholar 

del Pozo Cruz B, Ahmadi M, Naismith SL et al (2022) Association of daily step count and intensity with incident dementia in 78 430 adults living in the UK. JAMA Neurol 79(10):1059–1063

Article  PubMed  PubMed Central  Google Scholar 

Deutsche Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde (DGPPN), Deutsche Gesellschaft für Neurologie (2016) S3-Leitlinie „Demenzen“

Google Scholar 

Hamacher D, Hamacher D, Rehfeld K et al (2016) Motor-cognitive dual-task training improves local dynamic stability of normal walking in older individuals. Clin Biomech (Bristol, Avon) 32:138–141

Article  PubMed  Google Scholar 

Heimann B, Wallesch C‑W (2005) Diagnosis and differential diagnosis of mild cognitive impairment. Akt Neurol 32(07):423–439

Article  Google Scholar 

Herold F, Wiegel P, Scholkmann F et al (2017) Functional near-infrared spectroscopy in movement science: a systematic review on cortical activity in postural and walking tasks. Neurophoton 4(4):41403

Article  Google Scholar 

Jahn K, Heinze C, Selge C et al (2015) Gangstörungen beim geriatrischen Patienten. Klassifikation und Therapie. Nervenarzt 86(4):431–439

Article  CAS  PubMed  Google Scholar 

Janelidze M, Botchorishvili N (2018) Mild cognitive impairment. In: Dorszewska J, Kozubski W (Hrsg) Alzheimer’s disease—the 21st century challenge. InTech,

Google Scholar 

Kikkert LHJ, Vuillerme N, van Campen JP et al (2016) Walking ability to predict future cognitive decline in old adults: a scoping review. Ageing Res Rev 27:1–14

Article  PubMed  Google Scholar 

Kivipelto M, Mangialasche F, Ngandu T (2018) Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease. Nat Rev Neurol 14(11):653–666

Article  PubMed  Google Scholar 

Maguire FJ, Killane I, Creagh AP et al (2018) Baseline association of motoric cognitive risk syndrome with sustained attention, memory, and global cognition. J Am Med Dir Assoc 19(1):53–58

Article  PubMed  Google Scholar 

Marquez I, Garcia-Cifuentes E, Velandia FR et al (2022) Motoric cognitive risk syndrome: prevalence and cognitive performance. A cross-sectional study. Lancet Reg Health Am 8:100162

PubMed  Google Scholar 

Meiner Z, Ayers E, Verghese J (2020) Motoric cognitive risk syndrome: a risk factor for cognitive impairment and dementia in different populations. Ann Geriatr Med Res 24(1):3–14

Article  PubMed  PubMed Central  Google Scholar 

Michalowsky B, Kaczynski A, Hoffmann W (2019) Ökonomische und gesellschaftliche Herausforderungen der Demenz in Deutschland – Eine Metaanalyse. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62(8):981–992

Article  PubMed  Google Scholar 

Middleton A, Fritz SL, Lusardi M (2015) Walking speed: the functional vital sign. J Aging Phys Act 23(2):314–322

Article  PubMed  Google Scholar 

Moon Y, Sung J, An R et al (2016) Gait variability in people with neurological disorders: a systematic review and meta-analysis. Hum Mov Sci 47:197–208

Article  PubMed  Google Scholar 

Müller P, Rehfeld K, Schmicker M et al (2017) Evolution of neuroplasticity in response to physical activity in old age: the case for dancing. Front Aging Neurosci 9:56

Article  PubMed  PubMed Central  Google Scholar 

Müller P, Fendt M, Müller NG (2019) Pharmakologische Therapie der Alzheimer-Demenz : Aktueller Stand und Perspektiven. Internist (Berl) 60(7):761–768

Article  PubMed  Google Scholar 

Mullin DS, Cockburn A, Welstead M et al (2022) Mechanisms of motoric cognitive risk-hypotheses based on a systematic review and meta-analysis of longitudinal cohort studies of older adults. Alzheimers Dement 18(12):2413–2427. https://doi.org/10.1002/alz.12547

Article  PubMed  PubMed Central  Google Scholar 

Nichols E, Steinmetz JD, Vollset SE et al (2022) Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the global burden of disease study 2019. Lancet Public Health 7(2):e105–e125

Article  Google Scholar 

Pflüger M, Aebi C, Monsch AU (2003) Klinisches Untersuchungsverfahren. Z Klin Psychol Psychother 32(1):64–66

Article  Google Scholar 

Semba RD, Tian Q, Carlson MC et al (2020) Motoric cognitive risk syndrome: Integration of two early harbingers of dementia in older adults. Ageing Res Rev 58:101022

Article  CAS  PubMed  PubMed Central  Google Scholar 

Skillbäck T, Blennow K, Zetterberg H et al (2022) Slowing gait speed precedes cognitive decline by several years. Alzheimers Dement 18(9):1667–1676. https://doi.org/10.1002/alz.12537

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tian Q, Studenski SA, Montero-Odasso M et al (2021) Cognitive and neuroimaging profiles of older adults with dual decline in memory and gait speed. Neurobiol Aging 97:49–55

Article  PubMed  Google Scholar 

Verghese J, Wang C, Lipton RB et al (2013) Motoric cognitive risk syndrome and the risk of dementia. J Gerontol A Biol Sci Med Sci 68(4):412–418

Article  PubMed  Google Scholar 

Verghese J, Annweiler C, Ayers E et al (2014) Motoric cognitive risk syndrome: multicountry prevalence and dementia risk. Neurology 83(8):718–726

Article  PubMed  PubMed Central  Google Scholar 

Wilson J, Allcock L, Mc Ardle R et al (2019) The neural correlates of discrete gait characteristics in ageing: a structured review. Neurosci Biobehav Rev 100:344–369

Article  PubMed  PubMed Central  Google Scholar 

Yaqub A, Darweesh SKL, Dommershuijsen LJ et al (2022) Risk factors, neuroimaging correlates and prognosis of the motoric cognitive risk syndrome: a population-based comparison with mild cognitive impairment. Eur J Neurol 29(6):1587–1599

Article  PubMed  PubMed Central  Google Scholar 

Yuan P, Raz N (2014) Prefrontal cortex and executive functions in healthy adults: a meta-analysis of structural neuroimaging studies. Neurosci Biobehav Rev 42:180–192

Article  PubMed  Google Scholar 

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