Article title

Abstract

Keywords

Introduction

Memantine and mechanism of its effect discovery and its role in Alzheimer

Clinical Guidelines for the Use of Memantine in Dementia

NICE guidelines on the treatment of dementia

Cochrane: Memantine as a treatment for dementia

Memantin’s mechanism of action

Indications for starting treatment

Posology

Treatment withdrawal

Main contraindications or precautions

Improvement of psychological and behavioral symptoms associated with dementia and cognitive symptoms

Functional improvement of patients and quality of life

Impact in terms of healthcare care costs

Role of memantine in other neurodegenerative entities: frontotemporal dementia

Basic and memantine research

Conclusions

References