Progranulin

Frontotemporal dementia

Humanized mice

Preclinical model, RNAseq

Bacterial artificial chromosome

4′,6-diamidino-2-phenylindole

Differentially expressed genes

Frontotemporal Dementia

Frontotemporal Lobar Degeneration

Hypoxanthine-aminopterin-thymidine

Integrated optical density

Neuronal Ceroid Lipofuscinosis

Normalization factor 2

Standard error of the mean

University of British Columbia

All data described in this manuscript is included in supplementary material or available from databases referenced within the manuscript.

© 2023 The Authors. Published by Elsevier Inc.