Connolly SJ, Crowther M, Eikelboom JW, ANNEXA-4 Investigators, et al. Full study report of andexanet alfa for bleeding associated with factor Xa inhibitors. N Engl J Med. 2019;380(14):1326–35.
Article CAS PubMed PubMed Central Google Scholar
Tsivgoulis G, Wilson D, Katsanos AH, et al. Neuroimaging and clinical outcomes of oral anticoagulant-associated intracerebral hemorrhage. Ann Neurol. 2018;84(5):694–704. https://doi.org/10.1002/ana.25342. (Epub 2018 Oct 25).
Article CAS PubMed Google Scholar
Demchuk AM, Yue P, Zotova E, ANNEXA-4 Investigators, et al. Hemostatic efficacy and anti-FXa (Factor Xa) reversal with andexanet alfa in intracranial hemorrhage: ANNEXA-4 substudy. Stroke. 2021;52(6):2096–105. https://doi.org/10.1161/STROKEAHA.
Article CAS PubMed PubMed Central Google Scholar
Strein M, May S, Brophy GM. Anticoagulation reversal for intracranial hemorrhage in the era of the direct oral anticoagulants. Curr Opin Crit Care. 2020;26(2):122–8. https://doi.org/10.1097/MCC.0000000000000706.
Christensen H, Cordonnier C, Kõrv J, et al. European Stroke Organisation guideline on reversal of oral anticoagulants in acute intracerebral haemorrhage. Eur Stroke J. 2019;4(4):294–306.
Article PubMed PubMed Central Google Scholar
Steffel J, Collins R, Antz M, et al., External reviewers. 2021 European Heart Rhythm Association practical guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation. Europace. 2021;23(10):1612–76.
Greenberg SM, Ziai WC, Cordonnier C, et al, American Heart Association/American Stroke Association. 2022 guideline for the management of patients with spontaneous intracerebral hemorrhage: a guideline from the American Heart Association/American Stroke Association. Stroke. 2022;53(7):e282–361. https://doi.org/10.1161/STR.0000000000000407.
Moher D, Liberati A, Tetzlaff J, et al, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151(4):264–9.
Gómez-Outes A, Alcubilla P, Calvo-Rojas G, et al. Meta-analysis of reversal agents for severe bleeding associated with direct oral anticoagulants. J Am Coll Cardiol. 2021;77(24):2987–3001. https://doi.org/10.1016/j.jacc.2021.04.061.
Article CAS PubMed Google Scholar
Culbreth SE, Rimsans J, Sylvester K, et al. Andexanet alfa—the first 150 days. Am J Hematol. 2019;94(1):E21–4. https://doi.org/10.1002/ajh.25326. (Epub 2018 Nov 26).
Ammar AA, Ammar MA, Owusu KA, et al. Andexanet alfa versus 4-factor prothrombin complex concentrate for reversal of factor Xa inhibitors in intracranial hemorrhage. Neurocrit Care. 2021;35(1):255–61. https://doi.org/10.1007/s12028-020-01161-5. (Epub 2021 Jan 6).
Article CAS PubMed Google Scholar
Barra ME, Das AS, Hayes BD, et al. Evaluation of andexanet alfa and four-factor prothrombin complex concentrate (4F-PCC) for reversal of rivaroxaban- and apixaban-associated intracranial hemorrhages. J Thromb Haemost. 2020;18(7):1637–47. https://doi.org/10.1111/jth.14838. (Epub 2020 May 12).
Article CAS PubMed Google Scholar
Khadka S, Kasireddy V, Dhakal P. Institutional experience of using andexanet alfa. Cureus. 2020;12(7):e9173. https://doi.org/10.7759/cureus.9173.
Article PubMed PubMed Central Google Scholar
Vestal ML, Hodulik K, Mando-Vandrick J, et al. Andexanet alfa and four-factor prothrombin complex concentrate for reversal of apixaban and rivaroxaban in patients diagnosed with intracranial hemorrhage. J Thromb Thrombolysis. 2022;53(1):167–75. https://doi.org/10.1007/s11239-021-02495-3. (Epub 2021 Jun 8).
Article CAS PubMed Google Scholar
Stevens VM, Trujillo TC, Kiser TH, et al. Retrospective comparison of andexanet alfa and 4-factor prothrombin complex for reversal of factor Xa-inhibitor related bleeding. Clin Appl Thromb Hemost. 2021;27:10760296211039020. https://doi.org/10.1177/10760296211039020.
Article CAS PubMed PubMed Central Google Scholar
Bradshaw PG, Keegan S, Foertsch M, et al. Andexanet alfa after 4-factor PCC administration for intracranial hemorrhage: a case series. J Thromb Thrombolysis. 2022;54(2):295–300. https://doi.org/10.1007/s11239-022-02658-w. (Epub 2022 May 4).
Article CAS PubMed Google Scholar
Davis SEB, Dehne KA, Rubinos CA, et al. Difficulties detecting clinically relevant factor Xa inhibitor levels prior to reversal with andexanet alfa for intracranial hemorrhage. Neurohospitalist. 2022;12(2):276–9. https://doi.org/10.1177/19418744211048013. (Epub 2021 Sep 24).
Milioglou L, Liao K, Traeger J, et al. Reversal of factor Xa inhibitors associated intracranial haemorrhage at a tertiary medical centre. Blood Coagul Fibrinolysis. 2022;33(5):261–5. https://doi.org/10.1097/MBC.0000000000001128. (Epub 2022 Mar 7).
Article CAS PubMed Google Scholar
Morton C, Lista A, Jakowenko N, et al. Apixaban and rivaroxaban anti-Xa level utilization for guidance of administration of andexanet alfa: a case series. J Thromb Thrombolysis. 2022;53(1):235–9. https://doi.org/10.1007/s11239-021-02521-4. (Epub 2021 Jul 8).
Article CAS PubMed Google Scholar
Parsels KA, Seabury RW, Zyck S, et al. Andexanet alfa effectiveness and safety versus four-factor prothrombin complex concentrate (4F-PCC) in intracranial hemorrhage while on apixaban or rivaroxaban: a single-center, retrospective, matched cohort analysis. Am J Emerg Med. 2022;55:16–9. https://doi.org/10.1016/j.ajem.2022.02.036. (Epub 2022 Feb 24).
Rauch S, Müller HP, Dreyhaupt J, et al. Andexanet alfa for reversal of factor Xa inhibitors in intracranial hemorrhage: observational cohort study. J Clin Med. 2022;11(12):3399. https://doi.org/10.3390/jcm11123399.
Article CAS PubMed PubMed Central Google Scholar
Blackburn M. Four-factor prothrombin complex concentrate administration after expanding intracranial hemorrhage status post administration of andexanet alfa. Am J Emerg Med. 2022. https://doi.org/10.1016/j.ajem.2022.08.041. (Epub ahead of print).
Bradshaw PG, Keegan SP, Droege ME, et al. Reversal of apixaban and rivaroxaban with andexanet alfa prior to invasive or surgical procedures. Pharmacotherapy. 2022;42(10):780–91. https://doi.org/10.1002/phar.2727. (Epub 2022 Sep 23).
Article CAS PubMed PubMed Central Google Scholar
Brown CS, Scott RA, Sridharan M, et al. Real-world utilization of andexanet alfa. Am J Emerg Med. 2020;38(4):810–4. https://doi.org/10.1016/j.ajem.2019.12.008. (Epub 2019 Dec 10).
Schmidt LE, Hinton MS, Martin ND. Real-world reversal of factor Xa inhibition in the setting of major life-threatening bleeding or urgent surgery. J Pharm Pract. 2022. https://doi.org/10.1177/08971900221125516. (Epub ahead of print).
Giovino A, Shomo E, Busey KV, et al. An 18-month single-center observational study of real-world use of andexanet alfa in patients with factor Xa inhibitor associated intracranial hemorrhage. Clin Neurol Neurosurg. 2020;195:106070. https://doi.org/10.1016/j.clineuro.2020.106070.
Abdulrehman J, Eikelboom JW, Siegal DM. Andexanet alfa for reversal of factor Xa inhibitors: a critical review of the evidence. Future Cardiol. 2019;15(6):395–404. https://doi.org/10.2217/fca-2019-0038. (Epub 2019 Oct 31).
Article CAS PubMed Google Scholar
Abuan I, Wong KH, Bolinske B, et al. Andexanet alfa: a recombinant modified human factor Xa protein for drug reversal of rivaroxaban and apixaban. J Pharm Technol. 2019;35(3):119–25. https://doi.org/10.1177/8755122519839437. (Epub 2019 Mar 28).
Article CAS PubMed PubMed Central Google Scholar
Cuker A, Burnett A, Triller D, et al. Reversal of direct oral anticoagulants: guidance from the anticoagulation forum. Am J Hematol. 2019;94(6):697–709. https://doi.org/10.1002/ajh.25475.
Carpenter E, Singh D, Dietrich E, et al. Andexanet alfa for reversal of factor Xa inhibitor-associated anticoagulation. Ther Adv Drug Saf. 2019;26(10):2042098619888133. https://doi.org/10.1177/2042098619888133.
Cervi A, Crowther M. Andexanet alfa for the treatment of hemorrhage. Expert Rev Hematol. 2018;11(11):847–55. https://doi.org/10.1080/17474086.2018.1532287. (Epub 2018 Oct 17).
Article CAS PubMed Google Scholar
Favresse J, Hardy M, van Dievoet MA, et al. Andexanet alfa for the reversal of factor Xa inhibitors. Expert Opin Biol Ther. 2019;19(5):387–97. https://doi.org/10.1080/14712598.2019.1599355. (Epub 2019 Apr 11).
Article CAS PubMed Google Scholar
Heo YA. Andexanet alfa: first global approval. Drugs. 2018;78(10):1049–55. https://doi.org/10.1007/s40265-018-0940-4. (Erratum in: Drugs. 2018 Aug;78(12):1285).
Article CAS PubMed PubMed Central Google Scholar
Nederpelt CJ, Naar L, Krijnen P, et al. Andexanet alfa or prothrombin complex concentrate for factor Xa inhibitor reversal in acute major bleeding: a systematic review and meta-analysis. Crit Care Med. 2021;49(10):e1025–36. https://doi.org/10.1097/CCM.0000000000005059.
Article CAS PubMed Google Scholar
Powell J, Taylor J, Garland SG. Andexanet alfa: a novel factor Xa inhibitor reversal agent. Ann Pharmacother. 2019;53(9):940–6. https://doi.org/10.1177/1060028019835209. (Epub 2019 Feb 27).
Article CAS PubMed Google Scholar
Shrestha DB, Budhathoki P, Adhikari A, et al. Efficacy and safety of andexanet alfa for bleeding caused by factor Xa inhibitors: a systematic review and meta-analysis. Cureus. 2021;13(12):e20632. https://doi.org/10.7759/cureus.20632.
Article PubMed PubMed Central Google Scholar
Sible AM, Nawarskas JJ. Andexanet alfa for reversing factor Xa inhibition. Cardiol Rev. 2019;27(2):108–11. https://doi.org/10.1097/CRD.0000000000000230.
Ellington TM. A systematic and evidence-based review of published and pending reports of andexanet alfa. J Pharm Pract. 2020;33(4):465–70. https://doi.org/10.1177/0897190018822556. (Epub 2019 Jan 6).
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