Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment

Howlader N, Noone A, Krapcho M, Miller D, Brest A, Yu M, et al. Seer cancer statistics review, 1975–2016. Bethesda, MD: National Cancer Institute; 2019. p. 2019.

Google Scholar 

Simpson RJ, Lim JW, Moritz RL, Mathivanan S. Exosomes: proteomic insights and diagnostic potential. Expert Rev Proteomics. 2009;6(3):267–83.

Article  CAS  PubMed  Google Scholar 

Chen X, Liang H, Zhang J, Zen K, Zhang C-Y. Horizontal transfer of microRNAs: molecular mechanisms and clinical applications. Protein Cell. 2012;3(1):28–37.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9(6):654–9.

Article  CAS  PubMed  Google Scholar 

Cowland JB, Hother C, Grønbaek K. MicroRNAs and cancer. APMIS. 2007;115(10):1090–106.

Article  CAS  PubMed  Google Scholar 

Reddy SDN, Gajula RP, Pakala SB, Kumar R. MicroRNAs and cancer therapy: the next wave or here to stay? Cancer Biol Ther. 2010;9(7):479–82.

Article  CAS  PubMed  Google Scholar 

Ruan K, Fang X, Ouyang G. MicroRNAs: novel regulators in the hallmarks of human cancer. Cancer Lett. 2009;285(2):116–26.

Article  CAS  PubMed  Google Scholar 

Seto AG. The road toward microRNA therapeutics. Int J Biochem Cell Biol. 2010;42(8):1298–305.

Article  CAS  PubMed  Google Scholar 

Barh D, Malhotra R, Ravi B, Sindhurani P. MicroRNA let-7: an emerging next-generation cancer therapeutic. Curr Oncol. 2010;17(1):70.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nedaeinia R, Manian M, Jazayeri M, Ranjbar M, Salehi R, Sharifi M, et al. Circulating exosomes and exosomal microRNAs as biomarkers in gastrointestinal cancer. Cancer Gene Ther. 2017;24(2):48–56.

Article  CAS  PubMed  Google Scholar 

Köberle V, Pleli T, Schmithals C, Alonso EA, Haupenthal J, Bönig H, et al. Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers. PLoS ONE. 2013;8(9): e75184.

Article  PubMed  PubMed Central  Google Scholar 

Pegtel DM, Cosmopoulos K, Thorley-Lawson DA, van Eijndhoven MA, Hopmans ES, Lindenberg JL, et al. Functional delivery of viral miRNAs via exosomes. Proc Natl Acad Sci. 2010;107(14):6328–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Théry C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol. 2009;9(8):581–93.

Article  PubMed  Google Scholar 

Lin J, Li J, Huang B, Liu J, Chen X, Chen X-M, et al. Exosomes: novel biomarkers for clinical diagnosis. ScientificWorldJournal. 2015;2015:657086.

Milane L, Singh A, Mattheolabakis G, Suresh M, Amiji MM. Exosome mediated communication within the tumor microenvironment. J Control Release. 2015;219:278–94.

Article  CAS  PubMed  Google Scholar 

Silva J, Garcia V, Rodriguez M, Compte M, Cisneros E, Veguillas P, et al. Analysis of exosome release and its prognostic value in human colorectal cancer. Genes Chromosom Cancer. 2012;51(4):409–18.

Article  CAS  PubMed  Google Scholar 

McAndrews KM, Kalluri R. Mechanisms associated with biogenesis of exosomes in cancer. Mol Cancer. 2019;18(1):1–11.

Article  Google Scholar 

Saunderson SC, Dunn AC, Crocker PR, McLellan AD. CD169 mediates the capture of exosomes in spleen and lymph node. Blood J Am Soc Hematol. 2014;123(2):208–16.

CAS  Google Scholar 

Luo X, Burwinkel B, Tao S, Brenner H. MicroRNA signatures: novel biomarker for colorectal cancer? Cancer Epidemiol Prev Biomarkers. 2011;20(7):1272–86.

Article  CAS  Google Scholar 

Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A, et al. Syndecan–syntenin–ALIX regulates the biogenesis of exosomes. Nat Cell Biol. 2012;14(7):677–85.

Article  CAS  PubMed  Google Scholar 

Salehi M, Vafadar A, Khatami SH, Taheri-Anganeh M, Vakili O, Savardashtaki A, et al. Gastrointestinal cancer drug resistance: the role of exosomal miRNAs. Mol Biol Rep. 2022;49(3):2421–32.

Article  CAS  PubMed  Google Scholar 

Zhang Y, Liu Y, Liu H, Tang WH. Exosomes: biogenesis, biologic function and clinical potential. Cell Biosci. 2019;9(1):1–18.

Article  Google Scholar 

Brinton LT, Sloane HS, Kester M, Kelly KA. Formation and role of exosomes in cancer. Cell Mol Life Sci. 2015;72(4):659–71.

Article  CAS  PubMed  Google Scholar 

Gruenberg J, Van der Goot FG. Mechanisms of pathogen entry through the endosomal compartments. Nat Rev Mol Cell Biol. 2006;7(7):495–504.

Article  CAS  PubMed  Google Scholar 

Keller S, Sanderson MP, Stoeck A, Altevogt P. Exosomes: from biogenesis and secretion to biological function. Immunol Lett. 2006;107(2):102–8.

Article  CAS  PubMed  Google Scholar 

Huotari J, Helenius A. Endosome maturation. EMBO J. 2011;30(17):3481–500.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mayor S, Pagano RE. Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol. 2007;8(8):603–12.

Article  CAS  PubMed  Google Scholar 

Barile L, Vassalli G. Exosomes: therapy delivery tools and biomarkers of diseases. Pharmacol Ther. 2017;174:63–78.

Article  CAS  PubMed  Google Scholar 

Mathieu M, Martin-Jaular L, Lavieu G, Théry C. Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication. Nat Cell Biol. 2019;21(1):9–17.

Article  CAS  PubMed  Google Scholar 

Bebelman MP, Smit MJ, Pegtel DM, Baglio SR. Biogenesis and function of extracellular vesicles in cancer. Pharmacol Ther. 2018;188:1–11.

Article  CAS  PubMed  Google Scholar 

Kalluri R, LeBleu VS. The biology, function, and biomedical applications of exosomes. Science. 2020;367(6478):eaau6977.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Henne WM, Stenmark H, Emr SD. Molecular mechanisms of the membrane sculpting ESCRT pathway. Cold Spring Harb Perspect Biol. 2013;5(9): a016766.

Article  PubMed  PubMed Central  Google Scholar 

Rezaie J, Aslan C, Ahmadi M, Zolbanin NM, Kashanchi F, Jafari R. The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application. Cell Biosci. 2021;11(1):1–15.

Article  Google Scholar 

Subra C, Grand D, Laulagnier K, Stella A, Lambeau G, Paillasse M, et al. Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins [S]. J Lipid Res. 2010;51(8):2105–20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tschuschke M, Kocherova I, Bryja A, Mozdziak P, Angelova Volponi A, Janowicz K, et al. Inclusion biogenesis, methods of isolation and clinical application of human cellular exosomes. J Clin Med. 2020;9(2):436.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Van Niel G, Porto-Carreiro I, Simoes S, Raposo G. Exosomes: a common pathway for a specialized function. J Biochem. 2006;140(1):13–21.

Article  PubMed  Google Scholar 

Ren X, Hurley JH. VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo. EMBO J. 2010;29(6):1045–54.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kobayashi H, Tanaka N, Asao H, Miura S, Kyuuma M, Semura K, et al. Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2. J Biol Chem. 2005;280(11):10468–77.

Article  CAS  PubMed  Google Scholar 

Colombo M, Moita C, Van Niel G, Kowal J, Vigneron J, Benaroch P, et al. Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci. 2013;126(24):5553–65.

CAS  PubMed 

留言 (0)

沒有登入
gif