Das S, Yu S, Sakamori R, Stypulkowski E, Gao N. Wntless in Wnt secretion: molecular, cellular and genetic aspects. Front Biol (Beijing). 2012;7:587–93.
Article CAS PubMed Google Scholar
Bartscherer K, Pelte N, Ingelfinger D, Boutros M. Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell. 2006;125:523–33.
Article CAS PubMed Google Scholar
Banziger C, Soldini D, Schutt C, Zipperlen P, Hausmann G, Basler K. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 2006;125:509–22.
Article CAS PubMed Google Scholar
Nygaard R, Yu J, Kim J, Ross DR, Parisi G, Clarke OB, et al. Structural basis of WLS/Evi-mediated Wnt transport and secretion. Cell 2021;184:194.e14–206.e14.
Yu J, Chia J, Canning CA, Jones CM, Bard FA, Virshup DM. WLS retrograde transport to the endoplasmic reticulum during Wnt secretion. Dev Cell. 2014;29:277–91.
Article CAS PubMed Google Scholar
Chai G, Szenker-Ravi E, Chung C, Li Z, Wang L, Khatoo M, et al. A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. N Engl J Med. 2021;385:1292–301.
Article CAS PubMed PubMed Central Google Scholar
van Amerongen R, Berns A. Knockout mouse models to studyWnt signal transduction. Trends Genet. 2006;22:678–89.
Ikeya M, Lee S, Johnson J, McMahon A, Takada S. Wntsignalling required for expansion of neural crest and CNS pro-genitors. Nature 1997;389:966–70.
Article CAS PubMed Google Scholar
Preising MN, Görg B, Friedburg C, Qvartskhava N, Budde BS, Bonus M, et al. Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration. FASEB J 2019;33:11507–27. https://doi.org/10.1096/fj.201900914RR.
Article CAS PubMed Google Scholar
McMahon AP, Bradley A. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 1990;62:1073–85.
Article CAS PubMed Google Scholar
Rowitch DH, Danielian PS, McMahon AP, Zec N. Cystic malformation of the posterior cerebellar vermis transgenic mice that ectopically express engrailed-1, a homeodomain transcription factor. Teratology 1990;60:22–8.
Cavodeassi F, Carreira-Barbosa F, Young RM, Concha ML, Allende ML, Houart C, et al. Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway. Neuron 2005;47:43–56.
Article CAS PubMed PubMed Central Google Scholar
Liu C, Bakeri H, Li T, Swaroop A. Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet. 2012;21:1848–60.
Article CAS PubMed PubMed Central Google Scholar
Liu C, Widen SA, Williamson KA, Ratnapriya R, Gerth-Kahlert C, Rainger J, et al. A secreted WNT-ligand-binding domain of FZD5 generated by a frameshift mutation causes autosomal dominant coloboma. Hum Mol Genet. 2016;25:1382–91.
Article CAS PubMed PubMed Central Google Scholar
Hagglund AC, Berghard A, Carlsson L. Canonical Wnt/beta-catenin signalling is essential for optic cup formation. PLoS ONE. 2013;8:e81158.
Article PubMed PubMed Central Google Scholar
Lieven O, Ruther U. The Dkk1 dose is critical for eye development. Dev Biol. 2011;355:124–37.
Article CAS PubMed Google Scholar
Veien ES, Rosenthal JS, Kruse-Bend RC, Chien CB, Dorsky RI. Canonical Wnt signaling is required for the maintenance of dorsal retinal identity. Development. 2008;135:4101–11.
Article CAS PubMed Google Scholar
Joeng KS, Lee YC, Jiang MM, Bertin TK, Chen Y, Abraham AM, et al. The swaying mouse as a model of osteogenesis imperfect caused by WNT1 mutations. Hum Mol Genet. 2014;23:4035–42.
Article CAS PubMed PubMed Central Google Scholar
Keupp K, Beleggia F, Kayserili H, Barnes AM, Steiner M, Semler O, et al. Mutations in WNT1 cause different forms of bone fragility. Am J Hum Genet. 2013;92:565–74.
Article CAS PubMed PubMed Central Google Scholar
Tamura M, Nemoto E. Role of the Wnt signaling molecules in the tooth. Jpn Dent Sci Rev. 2016;52:75–83.
Article PubMed PubMed Central Google Scholar
Gowans GJ, Bridgers JB, Zhang J, Dronamraju R, Burnetti A, King DA, et al. Recognition of histone crotonylation by Taf14 links metabolic state to gene expression. Mol Cell 2019;76:909–21.
留言 (0)