Genetic associations between circulating metabolic biomarkers and lung cancer in East Asians and Europeans

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.

Article  PubMed  Google Scholar 

GBD 2019 Respiratory Tract Cancers Collaborators. Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the global burden of disease study 2019. Lancet Respir Med. 2021;9(9):1030–49.

Article  Google Scholar 

Hu Y, Zhang X, Ma Y, Yuan C, Wang M, Wu K, et al. Incident type 2 diabetes duration and cancer risk: a prospective study in two US cohorts. J Natl Cancer Inst. 2021;113(4):381–9.

Article  PubMed  Google Scholar 

Peila R, Rohan TE. Diabetes, glycated hemoglobin, and risk of cancer in the UK biobank study. Cancer Epidemiol Biomarkers Prev. 2020;29(6):1107–19.

Article  CAS  PubMed  Google Scholar 

Luo J, Hendryx M, Qi L, Ho GY, Margolis KL. Pre-existing diabetes and lung cancer prognosis. Br J Cancer. 2016;115(1):76–9.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Luo J, Chen YJ, Chang LJ. Fasting blood glucose level and prognosis in non-small cell lung cancer (NSCLC) patients. Lung Cancer. 2012;76(2):242–7.

Article  PubMed  Google Scholar 

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. Lancet. 2016;387(10027):1513–30.

Article  Google Scholar 

Smeland OB, Bahrami S, Frei O, Shadrin A, O’Connell K, Savage J, et al. Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence. Mol Psychiatry. 2020;25(4):844–53.

Article  CAS  PubMed  Google Scholar 

Tseng CH. Diabetes but not insulin increases the risk of lung cancer: a Taiwanese population-based study. PLoS ONE. 2014;9(7):e101553.

Article  PubMed Central  PubMed  Google Scholar 

Hao B, Yu M, Sang C, Bi B, Chen J. Dyslipidemia and non-small cell lung cancer risk in Chinese population: a case-control study. Lipids Health Dis. 2018;17(1):278.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Pedersen KM, Çolak Y, Bojesen SE, Nordestgaard BG. Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals. J Hematol Oncol. 2020;13(1):129.

Article  PubMed Central  PubMed  Google Scholar 

Jee SH, Ohrr H, Sull JW, Yun JE, Ji M, Samet JM. Fasting serum glucose level and cancer risk in Korean men and women. JAMA. 2005;293(2):194–202.

Article  CAS  PubMed  Google Scholar 

Stocks T, Rapp K, Bjørge T, Manjer J, Ulmer H, Selmer R, et al. Blood glucose and risk of incident and fatal cancer in the metabolic syndrome and cancer project (me-can): analysis of six prospective cohorts. PLoS Med. 2009;6(12):e1000201.

Article  PubMed Central  PubMed  Google Scholar 

Hall GC, Roberts CM, Boulis M, Mo J, MacRae KD. Diabetes and the risk of lung cancer. Diabetes Care. 2005;28(3):590–4.

Article  PubMed  Google Scholar 

Marrer É, Wagner A, Montaye M, Luc G, Amouyel P, Dallongeville J, et al. Lipoprotein(a) plasma levels and the risk of cancer: the PRIME study. Eur J Cancer Prev. 2013;22(3):286–93.

Article  CAS  PubMed  Google Scholar 

Zuber V, Grinberg NF, Gill D, Manipur I, Slob EAW, Patel A, et al. Combining evidence from Mendelian randomization and colocalization: review and comparison of approaches. Am J Hum Genet. 2022;109(5):767–82.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Zhou W, Liu G, Hung RJ, Haycock PC, Aldrich MC, Andrew AS, et al. Causal relationships between body mass index, smoking and lung cancer: univariable and multivariable Mendelian randomization. Int J Cancer. 2021;148(5):1077–86.

Article  CAS  PubMed  Google Scholar 

Zhou H, Zhang Y, Liu J, Yang Y, Fang W, Hong S, et al. Education and lung cancer: a Mendelian randomization study. Int J Epidemiol. 2019;48(3):743–50.

Article  PubMed  Google Scholar 

Wu X, Peng H, Wen Y, Cai X, Li C, Zhong R, et al. Rheumatoid arthritis and risk of lung cancer: meta-analysis and Mendelian randomization study. Semin Arthritis Rheum. 2021;51(3):565–75.

Article  CAS  PubMed  Google Scholar 

Kim YJ, Moon S, Hwang MY, Han S, Jang HM, Kong J, et al. The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians. Nat Commun. 2022;13(1):6642.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. 2021;600(7890):675–9.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, et al. Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nat Commun. 2021;12(1):24.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, et al. Impact of common genetic determinants of hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: a transethnic genome-wide meta-analysis. PLoS Med. 2017;14(9):e1002383.

Article  PubMed Central  PubMed  Google Scholar 

Sakaue S, Kanai M, Tanigawa Y, Karjalainen J, Kurki M, Koshiba S, et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nat Genet. 2021;53(10):1415–24.

Article  CAS  PubMed  Google Scholar 

McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, et al. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet. 2017;49(7):1126–32.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Burgess S, Thompson SG. Avoiding bias from weak instruments in Mendelian randomization studies. Int J Epidemiol. 2011;40(3):755–64.

Article  PubMed  Google Scholar 

Wu F, Huang Y, Hu J, Shao Z. Mendelian randomization study of inflammatory bowel disease and bone mineral density. BMC Med. 2020;18(1):312.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Liu Z, Suo C, Fan H, Zhang T, Jin L, Chen X. Dissecting causal relationships between nonalcoholic fatty liver disease proxied by chronically elevated alanine transaminase levels and 34 extrahepatic diseases. Metabolism. 2022;135:155270.

Article  CAS  PubMed  Google Scholar 

Sanderson E, Spiller W, Bowden J. Testing and correcting for weak and pleiotropic instruments in two-sample multivariable Mendelian randomization. Stat Med. 2021;40(25):5434–52.

Article  PubMed Central  PubMed  Google Scholar 

Davey Smith G, Hemani G. Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet. 2014;23(R1):R89-98.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Burgess S, Dudbridge F, Thompson SG. Combining information on multiple instrumental variables in mendelian randomization: comparison of allele score and summarized data methods. Stat Med. 2016;35(11):1880–906.

Article  PubMed  Google Scholar 

Verbanck M, Chen CY, Neale B, Do R. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet. 2018;50(5):693–8.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Burgess S, Thompson SG. Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects. Am J Epidemiol. 2015;181(4):251–60.

Article  PubMed Central  PubMed  Google Scholar 

Lin X, Liu L, Fu Y, Gao J, He Y, Wu Y, et al. Dietary cholesterol intake and risk of lung cancer: a meta-analysis. Nutrients. 2018. https://doi.org/10.3390/nu10020185.

Article  PubMed Central  PubMed  Google Scholar 

Lin X, Lu L, Liu L, Wei S, He Y, Chang J, et al. Blood lipids profile and lung cancer risk in a meta-analysis of prospective cohort studies. J Clin Lipidol. 2017;11(4):1073–81.

Article  PubMed  Google Scholar 

Chandler PD, Song Y, Lin J, Zhang S, Sesso HD, Mora S, et al. Lipid biomarkers and long-term risk of cancer in the women’s health study. Am J Clin Nutr. 2016;103(6):1397–407.

Article  CAS  PubMed Central  PubMed 

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