*Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan;

†Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan;

‡Industrial Technology Research Institute, Taipei City, Taiwan;

§Department of Materials Science and Engineering, National Tsing-Hua University, Taipei City, Taiwan; and

¶Division of Computer Science and Engineering, University of Michigan, Ann Arbor, Michigan.

Reprint requests: Yu-Chieh Ko, Department of Ophthalmology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei City 11217, Taiwan; e-mail: [email protected]

The study was supported by grants from the Ministry of Science and Technology, Taipei, Taiwan (MOST 109-2314-B-075-016 to Y.-C. Ko).

None of the authors has any financial/conflicting interests to disclose.

Conception and design: T.-C. Yeh, S.-J. Chen, Y.-B. Chou, A.-C. Luo, Y.-S. Deng, Y.-H. Lee, and Y.-C. Ko. Administrative support: P.-H. Chang, C.-J. Lin, and M.-C. Tai. Provision of study materials or patients: T.-C. Yeh, S.-J. Chen, Y.-B. Chou, and Y.-C. Ko. Collection and assembly of data: T.-C. Yeh and Y.-C. Ko. Data analysis and interpretation: T.-C. Yeh, A.-C. Luo, Y.-S. Deng, Y.-C. Chen, and Y.-C. Ko. Manuscript writing: T.-C. Yeh and Y.-C. Ko. Final approval of manuscript: All authors.

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Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Informed Consent Statement: Patient consent was waived as deemed by the Taipei Veterans General Hospital Institutional Review Board. IRB No for this study-TPEVGH IRB No.:2020-01-003BC.

Data Availability Statement: The data presented in this study are available on request from the corresponding author. The data are not publicly available due to patient privacy IRB requirement.