Relationship between prenatal checkup status and low birth weight: A nationwide birth cohort–the Japan Environment and Children’s Study

Elsevier

Available online 23 April 2023

Annals of EpidemiologyAuthor links open overlay panel, , , , AbstractPurpose

We investigated the association between prenatal checkup status and low birth weight (LBW). We also sought to identify the background factors of pregnant women that influence their attendance at prenatal checkups and consider measures that might prove useful in reducing the LBW rate.

Methods

Using data from a large nationwide birth cohort study, the Japan Environment and Children’s Study (JECS), the sample comprised 76,013 women. The outcome variable was cases of LBW and the exposure variable was prenatal checkup status (number of visits missed). Adjusted odds ratios (AORs) with 95% confidence intervals (CIs) were calculated by logistic regression analysis.

Results

AORs (95% CIs) for cases of LBW were 1.57 (1.48–1.71) for 1 missed checkup, 2.40 (1.97–2.94) for 2 missed checkups, and 2.38 (1.46–3.88) for ≥ 3 missed checkups. A linear trend was also observed (p <.0001). Further analysis revealed that the main risk factors for missed checkups were divorced or widowed marital status, followed by negative attitude toward pregnancy, and single marital status, whereas protective factors were being employed and better mental health in mid-late pregnancy.

Conclusions

Our results suggest the importance of implementing various measures to promote regular attendance at prenatal checkups.

Keywords

pregnancy

Low birth weight

Prenatal care

health checkup

© 2023 The Author(s). Published by Elsevier Inc.

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