Next generation risk assessment of human exposure to estrogens using safe comparator compound values based on in vitro bioactivity assays

Adir J, Caplan YH, Thompson BC (1978) Kepone® serum half-life in humans. Life Sci. https://doi.org/10.1016/0024-3205(78)90494-0

Article  PubMed  Google Scholar 

Adlercreutz H (1998) Epidemiology of phytoestrogens. Bailliere’s Clin Endocrinol Metabol. https://doi.org/10.1016/S0950-351X(98)80007-4

Article  Google Scholar 

Aguilar E, Crebelli R, Di Domenico A, Dusemund B, Frutos MJ, Galtier P, Gott D, Gundert-Remy U, Lambré C, Leblanc J-C, Lindtner O, Moldeus P, Mortensen A, Mosesso P, Parent-Massin D, Oskarsson A, Stankovic I, Waalkens-Berendsen I, Woutersen RA, Wright M, Younes M (2015) Risk assessment for peri- and post-menopausal women taking food supplements containing isolated isoflavones. EFSA J 13(10). https://doi.org/10.2903/j.efsa.2015.4246

Allen TEH, Goodman JM, Gutsell S, Russell PJ (2018) Using 2D structural alerts to define chemical categories for molecular initiating events. Toxicol Sci. https://doi.org/10.1093/toxsci/kfy144

Article  PubMed  Google Scholar 

ANSES (French Agency for Food, Environmental and Occupational Health and Safety) (2018a) AVIS de l’Agence nationale de securite sanitaire de l’alimentation, de l’environnement et du travail (ANSES) relatif a l’actualisation des donnees d’exposition par voie alimentaire afin d’evaluer les risques des populations antillaises et emettre des recommandations de consommation dans le cadre du projet Kannari «Sante, nutrition et exposition a la chlordecone aux Antilles» et aux limites maximales de residus (LMR) pour la chlordecone (2014-SA-0I09 and 2017-SA-0029). Available online: https://www.anses.fr/fr/system/files/ERCA2017SA0029.pdf. Accessed 4 Jan 2022

ANSES (French Agency for Food, Environmental and Occupational Health and Safety), 2018b. Note d’appui scientifique et technique de l’Agence nationale de securite sanitaire de l’alimentation, de l’environnement et du travail (ANSES) relative e a la fixation d’une limite maximale de residus de chlordecone dans la graisse pour les denrees carnees (2018b-SA-0202). Available online: https://www.anses.fr/fr/system/files/ERCA2018bSA0202.pdf. Accessed 4 Jan 2022

ANSES (French Agency for Food, Environmental and Occupational Health and Safety), 2019. Avis de l’Agence nationale de securite sanitaire de l’alimentation, de l’environnement et du travail (ANSES) relative e a la fixation d’une limite maximale de residus de chlordecone dans les muscles et dans la graisse pour les denrees carnees (2018-SA-0265).. Available online. https://www.anses.fr/fr/system/files/ERCA2018SA0265.pdf. Accessed 4 Jan 2022

Becker RA, Friedman KP, Simon TW, Marty MS, Patlewicz G, Rowlands JC (2015) An exposure: activity profiling method for interpreting high-throughput screening data for estrogenic activity-Proof of concept. Regul Toxicol Pharmacol. https://doi.org/10.1016/j.yrtph.2015.01.008

Article  PubMed  Google Scholar 

Bolarinwa A, Linseisen J (2005) Validated application of a new high-performance liquid chromatographic method for the determination of selected flavonoids and phenolic acids in human plasma using electrochemical detection. J Chromatogr B Anal Technol Biomed Life Sci. https://doi.org/10.1016/j.jchromb.2005.06.024

Article  Google Scholar 

Bonn M, Eydeler U, Barkworth M, Rovati LC (2009) Bioequivalence study of generic tablet formulations containing ethinylestradiol and chlormadinone acetate in healthy female volunteers. Arzneim-Forsch/drug Res. https://doi.org/10.1055/s-0031-1296455

Article  Google Scholar 

Busby MG, Jeffcoat AR, Bloedon LAT, Koch MA, Black T, Dix KJ, Heizer WD, Thomas BF, Hill JM, Crowell JA, Zeisel SH (2002) Clinical characteristics and pharmacokinetics of purified soy isoflavones: single–dose administration to healthy men. Am J Clin Nutr. https://doi.org/10.1093/ajcn/75.1.126

Article  PubMed  Google Scholar 

Cannon SB, Veazey JM, Jackson RS, Burse VW, Hayes C, Straub WE, Landrigan PJ, Liddle JA (1978) Epidemic kepone poisoning in chemical workers. Am J Epidemiol. https://doi.org/10.1093/oxfordjournals.aje.a112572

Article  PubMed  Google Scholar 

Coecke S, Ahr H, Blaauboer BJ, Bremer S, Casati S, Castell J, Combes R, Corvi R, Crespi CL, Cunningham ML, Elaut G, Eletti B, Freidig A, Gennari A, Ghersi-Egea JF, Guillouzo A, Hartung T, Hoet P, Ingelman-Sundberg M, Worth A (2006) Metabolism: a bottleneck in in vitro toxicological test development. ATLA Altern Lab Anim. https://doi.org/10.1177/026119290603400113

Article  PubMed  Google Scholar 

Dent MP, Li H, Carmichael PL, Martin FL (2019) Employing dietary comparators to perform risk assessments for anti-androgens without using animal data. Toxicol Sci. https://doi.org/10.1093/toxsci/kfy245

Article  PubMed  Google Scholar 

EFSA Scientific Committee, Hardy A, Benford D, Halldorsson T, Jeger MJ, Knutsen KH, More S, Mortensen A, Naegeli H, Noteborn H, Ockleford C, Ricci A, Rychen G, Silano V, Solecki R, Turck D, Aerts M, Bodin L, Davis A, Edler L, Gundert-Remy U, Sand S, Slob W, Bottex B, Abrahantes JC, Marques DC, Kass G, Schlatter JR (2017) Update: Guidance on the use of the benchmark dose approach in risk assessment. EFSA J 15(1):4658. https://doi.org/10.2903/j.efsa.2017.4658

Article  Google Scholar 

Elsenbrand G (2007) Isoflavones as phytoestrogens in food supplements and dietary foods for special medical purposes. Mol Nutr Food Res. https://doi.org/10.1002/mnfr.200700217

Article  Google Scholar 

Emeville E, Giusti A, Coumoul X, Thomé JP, Blanchet P, Multigner L (2015) Associations of plasma concentrations of dichlorodiphenyldichloroethylene and polychlorinated biphenyls with prostate cancer: a case–control study in Guadeloupe (French West Indies). Environ Health Perspect. https://doi.org/10.1289/ehp.1408407

Article  PubMed  Google Scholar 

Fan K, Xu J, Jiang K, Liu X, Meng J, di Mavungu JD, Guo W, Zhang Z, Jing J, Li H, Yao B, Li H, Zhao Z, Han Z (2019) Determination of multiple mycotoxins in paired plasma and urine samples to assess human exposure in Nanjing, China. Environ Pollut. https://doi.org/10.1016/j.envpol.2019.02.091

Article  PubMed  Google Scholar 

Frederiksen H, Jørgensen N, Andersson AM (2011) Parabens in urine, serum and seminal plasma from healthy Danish men determined by liquid chromatography-tandem mass spectrometry (LC-MS/MS). J Exp Sci Environ Epidemiol. https://doi.org/10.1038/jes.2010.6

Article  Google Scholar 

Freire C, Koifman RJ, Sarcinelli PN, Simões Rosa AC, Clapauch R, Koifman S (2013) Long-term exposure to organochlorine pesticides and thyroid status in adults in a heavily contaminated area in Brazil. Environ Res. https://doi.org/10.1016/j.envres.2013.09.001

Article  PubMed  Google Scholar 

Grace PB, Taylor JI, Low YL, Luben RN, Mulligan AA, Botting NP, Dowsett M, Welch AA, Khaw KT, Wareham NJ, Day NE, Bingham SA (2004) Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-Norfolk. Cancer Epidemiol Biomark Prevent. https://doi.org/10.1158/1055-9965.698.13.5

Article  Google Scholar 

Gülden M, Mörchel S, Tahan S, Seibert H (2002) Impact of protein binding on the availability and cytotoxic potency of organochlorine pesticides and chlorophenols in vitro. Toxicology. https://doi.org/10.1016/S0300-483X(02)00085-9

Article  PubMed  Google Scholar 

Guldner L, Multigner L, Héraud F, Monfort C, Pierre Thomé J, Giusti A, Kadhel P, Cordier S (2010) Pesticide exposure of pregnant women in Guadeloupe: ability of a food frequency questionnaire to estimate blood concentration of chlordecone. Environ Res. https://doi.org/10.1016/j.envres.2009.10.015

Article  PubMed  Google Scholar 

Guzelian PS (1992) The clinical toxicology of chlordecone as an example of toxicological risk assessment for man. Toxicol Lett. https://doi.org/10.1016/0378-4274(92)90236-D

Article  PubMed  Google Scholar 

Hargreaves DF, Potten CS, Harding C, Shaw LE, Morton MS, Roberts SA, Howell A, Bundred NJ (1999) Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast. J Clin Endocrinol Metabol. https://doi.org/10.1210/jc.84.11.4017

Article  Google Scholar 

Hess RA, Cooke PS (2018) Estrogen in the male: a historical perspective. Biol Reprod. https://doi.org/10.1093/biolre/ioy043

Article  PubMed  PubMed Central  Google Scholar 

Högberg J, Hanberg A, Berglund M, Skerfving S, Remberger M, Calafat AM, Filipsson AF, Jansson B, Johansson N, Appelgren M, Håkansson H (2008) Phthalate diesters and their metabolites in human breast milk, blood or serum, and urine as biomarkers of exposure in vulnerable populations. Environ Health Perspect. https://doi.org/10.1289/ehp.10788

Article  PubMed  Google Scholar 

Hosoda K, Furuta T, Ishii K (2011) Metabolism and disposition of isoflavone conjugated metabolites in humans after ingestion of Kinako. Drug Metabol Dispos. https://doi.org/10.1124/dmd.111.038281

Article  Google Scholar 

IARC (International Agency for Research on Cancer) (1979) Chlordecone IARC monographs on the evaluation of carcinogenic risk of chemicals to humans. Vol. 20. Some halogenated hydrocarbons. International Agency for Research on Cancer, Lyon France, p 67

Google Scholar 

Kadhel P, Monfort C, Costet N, Rouget F, Thomé JP, Multigner L, Cordier S (2014) Chlordecone exposure, length of gestation, and risk of preterm birth. Am J Epidemiol. https://doi.org/10.1093/aje/kwt313

Article  PubMed  Google Scholar 

Kezios KL, Liu X, Cirillo PM, Cohn BA, Kalantzi OI, Wang Y, Petreas MX, Park JS, Factor-Litvak P (2013) Dichlorodiphenyltrichloroethane (DDT), DDT metabolites and pregnancy outcomes. Reproduct Toxicol. https://doi.org/10.1016/j.reprotox.2012.10.013

Article  Google Scholar 

Khan SA, Chatterton RT, Michel N, Bryk M, Lee O, Ivancic D, Heinz R, Zalles CM, Helenowski IB, Jovanovic BD, Franke AA, Bosland MC, Wang J, Hansen NM, Bethke KP, Dew A, Coomes M, Bergan RC (2012) Soy isoflavone supplementation for breast cancer risk reduction: a randomized phase ii trial. Cancer Prevent Res. https://doi.org/10.1158/1940-6207.CAPR-11-0251

Article  Google Scholar 

Kolatorova Sosvorova L, Chlupacova T, Vitku J, Vlk M, Heracek J, Starka L, Saman D, Simkova M, Hampl R (2017) Determination of selected bisphenols, parabens and estrogens in human plasma using LC-MS/MS. Talanta. https://doi.org/10.1016/j.talanta.2017.05.070

Article  PubMed  Google Scholar 

Legler J, van den Brink CE, Brouwer A, Murk AJ, van der Saag PT, Vethaak AD, van der Burg B (1999) Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line. Toxicol Sci. https://doi.org/10.1093/toxsci/48.1.55

Article  PubMed  Google Scholar 

Liu J, Mi S, Du L, Li X, Li P, Jia K, Zhao J, Zhang H, Zhao W, Gao Y (2018) The associations between plasma phytoestrogens concentration and metabolic syndrome risks in Chinese population. PLoS ONE. https://doi.org/10.1371/journal.pone.0194639

Article  PubMed  PubMed Central  Google Scholar 

Madlensky L, Natarajan L, Tchu S, Pu M, Mortimer J, Flatt SW, Nikoloff DM, Hillman G, Fontecha MR, Lawrence HJ, Parker BA, Wu AHB, Pierce JP (2011) Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes. Clin Pharmacol Therapeut. https://doi.org/10.1038/clpt.2011.32

Article  Google Scholar 

Mathew J, Sanker P, Varacallo MP (2020) Plasma blood. StatPearls. StatPearls Publishing, Treasure Island, FL

Google Scholar 

Mayo Clinic Staff. Estrogens, Estrone (E1) and Estradiol (E2), Fractionated, Serum. Mayo Clinic, Mayo Foundation for Medical Education and Research. (2022a) https://pediatric.testcatalog.org/show/ESTF. Accessed 4 Jan 2022

Mayo Clinic Staff (2022b) Testosterone, Total and Free, Serum. Mayo Clinic, Mayo Foundation for Medical Education and Research, https://testcatalog.org/show/TGRP. Accessed 4 Jan 2022

Mendez-Catala DM, Wang Q, Rietjens IMCM (2021) PBK model-based prediction of intestinal microbial and host metabolism of zearalenone and consequences for its estrogenicity. Mol Nutr Food Res. https://doi.org/10.1002/mnfr.202100443

Article  PubMed  PubMed Central  Google Scholar 

Mescher AL (2009) Chapter 12: Blood. Junquiera’s Basic Histology: Text and Atlas, Twelfth. McGraw-Hill Education/Medical, pp 203–215

Google Scholar 

Meyer H, Bolarinwa A, Wolfram G, Linseisen J (2006) Bioavailability of apigenin from apiin-rich parsley in humans. Ann Nutr Metabol. https://doi.org/10.1159/000090736

Article  Google Scholar 

Minelli EV, Ribeiro ML (1996) DDT and HCH residues in the blood serum of malaria control sprayers. Bull Environ Contam Toxicol. https://doi.org/10.1007/s001289900245

Article  PubMed  Google Scholar 

Mollergues J, van Vugt-Lussenburg B, Kirchnawy C, Bandi RA, van der Lee RB, Marin-Kuan M, Schilter B, Fussell KC (2017) Incorporation of a metabolizing system in biodetection assays for endocrine active substances. Altex. https://doi.org/10.14573/altex.1611021

Article  PubMed  Google Scholar 

Multigner L, Kadhel P, Huc-Terki F, Thome JP, Janky E, Auger J (2006) Exposure to chlordecone and male fertility in guadeloupe (French West Indies). Epidemiology. https://doi.org/10.1097/00001648-200611001-00989

Article 

留言 (0)

沒有登入
gif