antigen presenting cells
ATF4activating transcription factor 4
ATF6activating transcription factor 6
BETBromodomain and extra-terminal domain
bZIPbasic Leucine Zipper domain
bHLH-LZbasic-helix-loop-helix-leucine zipper
CD47Cluster of Differentiation 47
CD24Cluster of Differentiation 24
CDKCyclin-dependent kinase
CHOPC/EBP Homologous Protein, encoded by DDIT3/GADD153
CINchromosome instability
CIMPCpG island methylation phenotype
CTLsCytotoxic T lymphocytes
CTLA-4Cytotoxic T lymphocyte-associated protein 4
cGAScyclic GMP-AMP synthase
DAMPsDamage-associated molecular patterns
4E-BP1eIF4E-binding protein 1
eIF2αEukaryotic translation initiation factor 2 alpha,encoded by EIF2S1
FDAFood and Drug Administration
FOLFIRIFolinic acid, 5-fluorouracil and irinotecan
FOLFOXFolinic acid, 5-fluorouracil and oxaliplatin
GCN2general control nonderepressible 2, encoded by EIF2AK4
GRP78Glucose-Regulated Protein 78
GADD153Growth arrest and DNA damage-inducible protein
GSK3glycogen synthase kinase 3
HAThistone acetyltransferases
HMGB1high-mobility group box 1
HRIHeme-Regulated Inhibitor, encoded by EIF2AK1
ICBImmune checkpoint blockade
ICDImmunogenic cell death
IRE1inositol-requiring enzyme1
IRE1αInositol-requiring transmembrane kinase/endoribonuclease 1α
ISRIntegrated stress response
IKKαInhibitor of nuclear factor kappa-B kinase subunit alpha
IKKβInhibitor of nuclear factor kappa-B kinase subunit beta
MaxMyc-associated protein X
Miz-1Myc-interacting zinc finger protein 1
MHCMajor histocompatibility complex
MSIMicrosatellite instability
MDSCsmyeloid-derived suppressor cells
NKG2Dnatural killer group 2D
NF-kBnuclear factor kappa-B
PDL-1Programmed Death Ligand 1
PERKPKR-Like ER Kinase, encoded by EIF2AK3
PDOpatient derived organoids
PDXpatient derived xenografts
PROTACsProteolysis-targeting chimaeras
PKRprotein kinase R, encoded by EIF2AK2
PUMAp53 upregulated modulator of apoptosis
PPIprotein-protein interaction
RNA Pol IIRNA polymerase II
RIDDregulated IRE1α-dependent decay
STAT1signal transducer and activator of transcription 1
SCD1stearoyl-CoA desaturase 1
SPOPSpeckle-type POZ protein
STING1Stimulator of interferon genes 1
TADamino-terminal transactivation domain
TRIB3Tribbles Pseudokinase 3
TMETumor microenvironment
T-ALLT-cell acute lymphoblastic leukemia
UPRUnfolded protein response
USP7Ubiquitin Specific Peptidase 7
XBP1X-box-binding protein 1
YAPYes- Associated Protein 1
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