Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.

Article  PubMed  Google Scholar 

Lui RN, Tsoi KKF, Ho JMW, Lo CM, Chan FCH, Kyaw MH, et al. Global increasing incidence of Young-Onset Colorectal Cancer Across 5 continents: a Joinpoint Regression Analysis of 1,922,167 cases. Cancer Epidemiol Biomarkers Prev. 2019;28:1275–82.

Article  PubMed  Google Scholar 

Chambers AC, Dixon SW, White P, Williams AC, Thomas MG, Messenger DE. Demographic trends in the incidence of young-onset colorectal cancer: a population-based study. Br J Surg. 2020;107:595–605.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Burnett-Hartman AN, Lee JK, Demb J, Gupta S. An update on the epidemiology, molecular characterization, diagnosis, and screening strategies for early-onset Colorectal Cancer. Gastroenterology. 2021;160:1041–9.

Article  PubMed  Google Scholar 

Yehuda-Shnaidman E, Schwartz B. Mechanisms linking obesity, inflammation and altered metabolism to colon carcinogenesis. Obes Rev. 2012;13:1083–95.

Article  CAS  PubMed  Google Scholar 

Saltiel AR, Olefsky JM. Inflammatory mechanisms linking obesity and metabolic disease. J Clin Invest. 2017;127:1–4.

Article  PubMed  PubMed Central  Google Scholar 

Tarasiuk A, Mosinska P, Fichna J. The mechanisms linking obesity to colon cancer: an overview. Obes Res Clin Pract. 2018;12:251–9.

Article  PubMed  Google Scholar 

Khan S, Luck H, Winer S, Winer DA. Emerging concepts in intestinal immune control of obesity-related metabolic disease. Nat Commun. 2021;12:2598.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Amano K, Bruera E, Hui D. Diagnostic and prognostic utility of phase angle in patients with cancer.Rev Endocr Metab Disord. 2022.

de Onis M, Habicht JP. Anthropometric reference data for international use: recommendations from a World Health Organization Expert Committee. Am J Clin Nutr. 1996;64:650–8.

Article  PubMed  Google Scholar 

Thomas DM, Bredlau C, Bosy-Westphal A, Mueller M, Shen W, Gallagher D, et al. Relationships between body roundness with body fat and visceral adipose tissue emerging from a new geometrical model. Obes (Silver Spring). 2013;21:2264–71.

Article  Google Scholar 

Wu M, Yu X, Xu L, Wu S, Tian Y. Associations of longitudinal trajectories in body roundness index with mortality and cardiovascular outcomes: a cohort study. Am J Clin Nutr. 2022;115:671–8.

Article  PubMed  Google Scholar 

Wang J, Wu M, Wu S, Tian Y. Relationship between body roundness index and the risk of heart failure in chinese adults: the Kailuan cohort study. ESC Heart Fail. 2022;9:1328–37.

Article  PubMed  PubMed Central  Google Scholar 

Li Y, He Y, Yang L, Liu Q, Li C, Wang Y, et al. Body roundness Index and Waist-Hip ratio result in Better Cardiovascular Disease Risk Stratification: results from a large chinese cross-sectional study. Front Nutr. 2022;9:801582.

Article  PubMed  PubMed Central  Google Scholar 

Zhao Q, Zhang K, Li Y, Zhen Q, Shi J, Yu Y, et al. Capacity of a body shape index and body roundness index to identify diabetes mellitus in Han chinese people in Northeast China: a cross-sectional study. Diabet Med. 2018;35:1580–7.

Article  CAS  PubMed  Google Scholar 

Rico-Martin S, Calderon-Garcia JF, Sanchez-Rey P, Franco-Antonio C, Martinez Alvarez M, Sanchez Munoz-Torrero JF. Effectiveness of body roundness index in predicting metabolic syndrome: a systematic review and meta-analysis. Obes Rev. 2020;21:e13023.

Article  PubMed  Google Scholar 

Li ZY, Tan YT, Wang J, Fang J, Liu DK, Li HL, et al. Dose-response relationship between fat distribution and liver cancer incidence: a prospective cohort study in chinese men. Cancer Epidemiol. 2022;76:102091.

Article  PubMed  Google Scholar 

Bo LL, Wang YQ, Liu YY, Li XD, Zhou R, Wang JL. [Analyze of obesity indicators and effect of fertility preservation treatment in patients with endometrial atypical hyperplasia and early endometrial cancer]. Zhonghua fu chan ke za zhi. 2022;57:767–74.

CAS  PubMed  Google Scholar 

Piche ME, Tchernof A, Despres JP. Obesity phenotypes, diabetes, and Cardiovascular Diseases. Circ Res. 2020;126:1477–500.

Article  CAS  PubMed  Google Scholar 

Caballero B. Humans against obesity: who Will Win? Adv Nutr. 2019;10:4–S9.

Article  Google Scholar 

Gallagher EJ, LeRoith D. Obesity and cancer. Cancer Metastasis Rev. 2022;41:463–4.

Article  PubMed  Google Scholar 

Avgerinos KI, Spyrou N, Mantzoros CS, Dalamaga M. Obesity and cancer risk: emerging biological mechanisms and perspectives. Metabolism. 2019;92:121–35.

Article  CAS  PubMed  Google Scholar 

Cifarelli V, Appak-Baskoy S, Peche VS, Kluzak A, Shew T, Narendran R, et al. Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells. Nat Commun. 2021;12:3350.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lu Y, Tang H, Huang P, Wang J, Deng P, Li Y, et al. Assessment of causal effects of visceral adipose tissue on risk of cancers: a mendelian randomization study. Int J Epidemiol. 2022;51:1204–18.

Article  PubMed  PubMed Central  Google Scholar 

Kim JM, Chung E, Cho ES, Lee JH, Shin SJ, Lee HS, et al. Impact of subcutaneous and visceral fat adiposity in patients with colorectal cancer. Clin Nutr. 2021;40:5631–8.

Article  CAS  PubMed  Google Scholar 

Calderon-Garcia JF, Roncero-Martin R, Rico-Martin S, De Nicolas-Jimenez JM, Lopez-Espuela F, Santano-Mogena E et al. Effectiveness of Body Roundness Index (BRI) and a Body Shape Index (ABSI) in Predicting Hypertension: A Systematic Review and Meta-Analysis of Observational Studies.Int J Environ Res Public Health. 2021;18.

Andreasson A, Hagstrom H, Skoldberg F, Onnerhag K, Carlsson AC, Schmidt PT, et al. The prediction of colorectal cancer using anthropometric measures: a swedish population-based cohort study with 22 years of follow-up. United Eur Gastroenterol J. 2019;7:1250–60.

Article  Google Scholar 

Parra-Soto S, Malcomson FC, Ho FK, Pell JP, Sharp L, Mathers JC, et al. Associations of a body shape index (ABSI) with Cancer incidence, All-Cause, and at 23 Sites-Findings from the UK Biobank prospective cohort study. Cancer Epidemiol Biomarkers Prev. 2022;31:315–24.

Article  PubMed  Google Scholar 

Jochems SHJ, Wood AM, Haggstrom C, Orho-Melander M, Stattin P, Stocks T. Waist circumference and a body shape index and prostate cancer risk and mortality. Cancer Med. 2021;10:2885–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lauby-Secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, Straif K, et al. Body fatness and Cancer–viewpoint of the IARC Working Group. N Engl J Med. 2016;375:794–8.

Article  PubMed  PubMed Central  Google Scholar 

Arnold M, Pandeya N, Byrnes G, Renehan PAG, Stevens GA, Ezzati PM, et al. Global burden of cancer attributable to high body-mass index in 2012: a population-based study. Lancet Oncol. 2015;16:36–46.

Article  PubMed  Google Scholar 

Arnold M, Touillaud M, Dossus L, Freisling H, Bray F, Margaritis I, et al. Cancers in France in 2015 attributable to high body mass index. Cancer Epidemiol. 2018;52:15–9.

Article  PubMed  Google Scholar 

Pearson-Stuttard J, Zhou B, Kontis V, Bentham J, Gunter MJ, Ezzati M. Worldwide burden of cancer attributable to diabetes and high body-mass index: a comparative risk assessment. Lancet Diabetes Endocrinol. 2018;6:e6–e15.

Article  PubMed  PubMed Central  Google Scholar 

O’Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N et al. Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2022;20:1229-40.e5.

Kyrgiou M, Kalliala I, Markozannes G, Gunter MJ, Paraskevaidis E, Gabra H, et al. Adiposity and cancer at major anatomical sites: umbrella review of the literature. BMJ. 2017;356:j477.

Article  PubMed  PubMed Central  Google Scholar 

Vuik FE, Nieuwenburg SA, Bardou M, Lansdorp-Vogelaar I, Dinis-Ribeiro M, Bento MJ, et al. Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years. Gut. 2019;68:1820–6.

Article  PubMed  Google Scholar 

Wong MC, Chan CH, Cheung W, Fung DH, Liang M, Huang JL, et al. Association between investigator-measured body-mass index and colorectal adenoma: a systematic review and meta-analysis of 168,201 subjects. Eur J Epidemiol. 2018;33:15–26.

Article  PubMed  Google Scholar 

Knudsen MD, Berstad P, Hjartaker A, Gulichsen EH, Hoff G, de Lange T, et al. Lifestyle predictors for non-participation and outcome in the second round of faecal immunochemical test in colorectal cancer screening. Br J Cancer. 2017;117:461–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Unanue-Arza S, Solis-Ibinagagoitia M, Diaz-Seoane M, Mosquera-Metcalfe I, Idigoras I, Bilbao I, et al. Inequalities and risk factors related to non-participation in colorectal cancer screening programmes: a systematic review. Eur J Public Health. 2021;31:346–55.

Article  PubMed  Google Scholar 

Nielsen JB, Berg-Beckhoff G, Leppin A. To do or not to do - a survey study on factors associated with participating in the danish screening program for colorectal cancer. BMC Health Serv Res. 2021;21:43.

Article  PubMed  PubMed Central