Rudnick SI, Adams GP (2009) Affinity and avidity in antibody-based tumor targeting. Cancer Biother Radiopharm 24:155–161
CAS PubMed PubMed Central Google Scholar
Vivier D, Sharma SK, Zeglis BM (2018) Understanding the in vivo fate of radioimmunoconjugates for nuclear imaging. J Labelled Comp Radiopharm 61:672–692
Article CAS PubMed PubMed Central Google Scholar
Wu AM (2009) Antibodies and Antimatter: The resurgence of immuno-PET. J Nucl Med 50:2–5
Article CAS PubMed Google Scholar
Sharma SK, Glaser JM, Edwards KJ et al (2021) A systematic evaluation of antibody modification and (89)Zr-radiolabeling for optimized immuno-PET. Bioconjug Chem 32:1177–1191
Article CAS PubMed Google Scholar
Tavaré R, Wu WH, Zettlitz KA et al (2014) Enhanced immunoPET of ALCAM-positive colorectal carcinoma using site-specific (64)Cu-DOTA conjugation. Protein Eng Des Sel 27:317–324
Article PubMed PubMed Central Google Scholar
Agarwal P, Bertozzi CR (2015) Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development. Bioconjug Chem 26:176–192
Article CAS PubMed Google Scholar
Jeger S, Zimmermann K, Blanc A et al (2010) Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase. Angew Chem Int Ed Engl 49:9995–9997
Article CAS PubMed Google Scholar
Ahn SH, Vaughn BA, Solis WA, Lupher ML Jr, Hallam TJ, Boros E (2020) Site-specific (89)Zr- and (111)In-radiolabeling and in vivo evaluation of glycan-free antibodies by azide-alkyne cycloaddition with a non-natural amino acid. Bioconjug Chem 31:1177–1187
Article CAS PubMed Google Scholar
Adumeau P, Sharma SK, Brent C, Zeglis BM (2016) Site-specifically labeled immunoconjugates for molecular imaging – Part 1: Cysteine residues and glycans. Mol Imaging Biol 18:1–17
Article CAS PubMed PubMed Central Google Scholar
Adumeau P, Sharma SK, Brent C, Zeglis BM (2016) Site-specifically labeled immunoconjugates for molecular imaging – Part 2: Peptide tags and unnatural amino Acids. Mol Imaging Biol 18:153–165
Article CAS PubMed PubMed Central Google Scholar
Jendeberg L, Tashiro M, Tejero R et al (1996) The mechanism of binding staphylococcal protein A to immunoglobin G does not involve helix unwinding. Biochemistry 35:22–31
Article CAS PubMed Google Scholar
Konrad A, Karlström AE, Hober S (2011) Covalent immunoglobulin labeling through a photoactivable synthetic Z domain. Bioconjug Chem 22:2395–2403
Article CAS PubMed Google Scholar
Ultsch M, Braisted A et al (2017) 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix. Protein Eng Des Sel 30:619–625
Article CAS PubMed PubMed Central Google Scholar
Perols A, Karlström AE (2014) Site-specific photoconjugation of antibodies using chemically synthesized IgG-binding domains. Bioconjug Chem 25:481–488
Article CAS PubMed Google Scholar
Kanje S, Hober S (2015) In vivo biotinylation and incorporation of a photo-inducible unnatural amino acid to an antibody-binding domain improve site-specific labeling of antibodies. Biotechnol J 10:564–574
Article CAS PubMed Google Scholar
Stiller C, Aghelpasand H, Frick T, Westerlund K, Ahmadian A, Karlström AE (2019) Fast and efficient Fc-specific photoaffinity labeling to produce antibody-DNA conjugates. Bioconjug Chem 30:2790–2798
Article CAS PubMed Google Scholar
von Witting E, Hober S, Kanje S (2021) Affinity-based methods for site-specific conjugation of antibodies. Bioconjug Chem 32:1515–1524
Westerlund K, Vorobyeva A, Mitran B et al (2019) Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting. Biomaterials 203:73–85
Article CAS PubMed Google Scholar
King DJ, Antoniw P, Owens RJ et al (1995) Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy. Br J Cancer 72:1364–1372
Article CAS PubMed PubMed Central Google Scholar
Lee FT, Hall C, Rigopoulos A et al (2001) Immuno-PET of human colon xenograft- bearing BALB/c nude mice using (124)I-CDR-grafted humanized A33 monoclonal antibody. J Nucl Med 42:764–769
Zeglis BM, Lewis JS (2011) A practical guide to the construction of radiometallated bioconjugates for positron emission tomography. Dalton Trans 40:6168–6195
Article CAS PubMed PubMed Central Google Scholar
Carrasquillo JA, Pandit-Taskar N, O’Donoghue JA et al (2011) (124)I-huA33 antibody PET of colorectal cancer. J Nucl Med 52:1173–1180
Zeglis BM, Lewis JS (2015) The bioconjugation and radiosynthesis of (89)Zr-DFO-labeled antibodies. JoVE (96):e52521
Cook BE, Adumeau P, Membreno R et al (2016) Pretargeted PET imaging using a site-specifically labeled immunoconjugate. Bioconjug Chem 27:1789–1795
Article CAS PubMed PubMed Central Google Scholar
Adumeau P, Davydova M, Zeglis BM (2018) Thiol-reactive bifunctional chelators for the creation of site-selectively modified radioimmunoconjugates with improved stability. Bioconjug Chem 29:1364–1372
Article CAS PubMed PubMed Central Google Scholar
Heath JK, White SJ, Johnstone CN et al (1997) The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily. Proc Natl Acad Sci USA 94:469–474
Article CAS PubMed PubMed Central Google Scholar
Höglund J, Orlova A, Sundin A, Lundqvist H, Tolmachev V (2006) Cellular processing in the SW1222 cell line of mAb A33 directly and indirectly radiohalogenated. Oncol Rep 16:159–163
Vosjan MJ, Perk LR, Visser GW et al (2010) Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine. Nat Protoc 5:739–743
Article CAS PubMed Google Scholar
Myrhammar A, Vorobyeva A et al (2020) Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting. Sci Rep 10:20777
Article CAS PubMed PubMed Central Google Scholar
Gogesch P, Dudek S, van Zandbergen G et al (2021) The role of Fc receptors on the effectiveness of therapeutic monoclonal antibodies. Int J Mol Sci 22:8947
Article CAS PubMed PubMed Central Google Scholar
Pyzik M, Rath T, Lencer WI et al (2015) FcRn: the architect behind the immune and nonimmune functions of IgG and albumin. J Immunol 194:4595–4603
Article CAS PubMed Google Scholar
Sharma SK, Suzuki M, Xu H et al (2022) Influence of Fc modifications and IgG subclass on biodistribution of humanized antibodies targeting L1CAM. J Nucl Med 63:629–636
Article CAS PubMed PubMed Central Google Scholar
Braisted AC, Wells JA (1996) Minimizing a binding domain from protein A. Proc Natl Acad Sci USA 93:5688–5692
Article CAS PubMed PubMed Central Google Scholar
Choe W, Durgannavar TA, Chung SJ (2016) Fc-binding ligands of immunoglobulin G: an overview of high affinity proteins and peptides. Materials 9:994
Article PubMed PubMed Central Google Scholar
Sockolosky JT, Kivimäe S, Szoka FC (2014) Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice. PLoS ONE 9:e102566
留言 (0)