Unbiased Human Kidney Tissue Proteomics Identifies Matrix Metalloproteinase 7 as a Kidney Disease Biomarker

1Department of Medicine, Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

2Institute of Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, Pennsylvania

3Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

4Research Division, Joslin Diabetes Center, One Joslin Place, Boston, Massachusetts;

5Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland

6Beth Israel Deaconess Medical Center, Boston, Massachusetts

7Department of Medicine, Harvard Medical School, Boston, Massachusetts

8School of Medicine, Tulane University, New Orleans, Louisiana

9Novo Nordisk Research Center Seattle Inc, Seattle, Washington

10Department of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania

11Department of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland

12Department of Medicine, Division of Precision Medicine, New York University. New York, NY;

*Address for correspondence: Monika Niewczas, M.D., Ph.D., M.P.H, Research Division, Joslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA 02215, Tel: 617-309-4552, E-mail: [email protected], Katalin Susztak, M.D., Ph.D, Perelman School of Medicine, University of Pennsylvania, 12-123 Smilow Translational Research Center, 3400 Civic Center Blvd, Philadelphia, PA 19104, Tel: 215-898-2009, E-mail: [email protected]

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