Glucocorticoids and cognitive function: a walkthrough in endogenous and exogenous alterations

Takahashi K, Totsune K, Sone M, Murakami O, Satoh F, Arihara Z et al (1998) Regional distribution of urocortin-like immunoreactivity and expression of urocortin mRNA in the human brain. Peptides 19(4):643–647

Article  CAS  PubMed  Google Scholar 

Claes SJ (2004) Corticotropin-releasing hormone (CRH) in psychiatry: from stress to psychopathology. Ann Med 36(1):50–61. https://doi.org/10.1080/07853890310017044

Article  CAS  PubMed  Google Scholar 

Keck ME, Holsboer F, Muller MB (2004) Mouse mutants for the study of corticotropin-releasing hormone receptor function: development of novel treatment strategies for mood disorders. Ann N Y Acad Sci 1018:445–457. https://doi.org/10.1196/annals.1296.055

Article  CAS  PubMed  Google Scholar 

Gravanis A, Margioris AN (2005) The corticotropin-releasing factor (CRF) family of neuropeptides in inflammation: potential therapeutic applications. Curr Med Chem 12(13):1503–1512

Article  CAS  PubMed  Google Scholar 

Smagin GN, Heinrichs SC, Dunn AJ (2001) The role of CRH in behavioral responses to stress. Peptides 22(5):713–724

Article  CAS  PubMed  Google Scholar 

Bale TL, Vale WW (2004) CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol 44:525–557. https://doi.org/10.1146/annurev.pharmtox.44.101802.121410

Article  CAS  PubMed  Google Scholar 

Sapolsky RM, Krey LC, McEwen BS (1986) The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocr Rev 7(3):284–301. https://doi.org/10.1210/edrv-7-3-284

Article  CAS  PubMed  Google Scholar 

Chrousos GP (2009) Stress and disorders of the stress system. Nat Rev Endocrinol 5(7):374–381. https://doi.org/10.1038/nrendo.2009.106

Article  CAS  PubMed  Google Scholar 

Logan RW, McClung CA (2019) Rhythms of life: circadian disruption and brain disorders across the lifespan. Nat Rev Neurosci 20(1):49–65. https://doi.org/10.1038/s41583-018-0088-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

de Kloet ER, Sutanto W, van den Berg DT, Carey MP, van Haarst AD, Hornsby CD et al (1993) Brain mineralocorticoid receptor diversity: functional implications. J Steroid Biochem Mol Biol 47(1–6):183–190. https://doi.org/10.1016/0960-0760(93)90073-6

Article  PubMed  Google Scholar 

Arriza JL, Simerly RB, Swanson LW, Evans RM (1988) The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron 1(9):887–900. https://doi.org/10.1016/0896-6273(88)90136-5

Article  CAS  PubMed  Google Scholar 

de Kloet ER, Van Acker SA, Sibug RM, Oitzl MS, Meijer OC, Rahmouni K et al (2000) Brain mineralocorticoid receptors and centrally regulated functions. Kidney Int 57(4):1329–1336. https://doi.org/10.1046/j.1523-1755.2000.00971.x

Article  PubMed  Google Scholar 

de Kloet ER, Otte C, Kumsta R, Kok L, Hillegers MH, Hasselmann H et al (2016) Stress and depression: a crucial role of the mineralocorticoid receptor. J Neuroendocrinol. https://doi.org/10.1111/jne.12379

Article  PubMed  Google Scholar 

Wingard JC, Packard MG (2008) The amygdala and emotional modulation of competition between cognitive and habit memory. Behav Brain Res 193(1):126–131. https://doi.org/10.1016/j.bbr.2008.05.002

Article  PubMed  Google Scholar 

Vogel S, Klumpers F, Schroder TN, Oplaat KT, Krugers HJ, Oitzl MS et al (2017) Stress induces a shift towards striatum-dependent stimulus-response learning via the mineralocorticoid receptor. Neuropsychopharmacology 42(6):1262–1271. https://doi.org/10.1038/npp.2016.262

Article  CAS  PubMed  Google Scholar 

Holmes MC, Yau JL, Kotelevtsev Y, Mullins JJ, Seckl JR (2003) 11 Beta-hydroxysteroid dehydrogenases in the brain: two enzymes two roles. Ann N Y Acad Sci 1007:357–366

Article  CAS  PubMed  Google Scholar 

Konstantakou P, Mastorakos G, Vrachnis N, Tomlinson JW, Valsamakis G (2017) Dysregulation of 11beta-hydroxysteroid dehydrogenases: implications during pregnancy and beyond. J Matern Fetal Neonatal Med 30(3):284–293. https://doi.org/10.3109/14767058.2016.1171308

Article  CAS  PubMed  Google Scholar 

Gathercole LL, Lavery GG, Morgan SA, Cooper MS, Sinclair AJ, Tomlinson JW et al (2013) 11beta-hydroxysteroid dehydrogenase 1: translational and therapeutic aspects. Endocr Rev 34(4):525–555. https://doi.org/10.1210/er.2012-1050

Article  CAS  PubMed  Google Scholar 

Stewart PM, Whorwood CB, Mason JI (1995) Type 2 11 beta-hydroxysteroid dehydrogenase in foetal and adult life. J Steroid Biochem Mol Biol 55(5–6):465–471

Article  CAS  PubMed  Google Scholar 

Alfaidy N, Li W, MacIntosh T, Yang K, Challis J (2003) Late gestation increase in 11beta-hydroxysteroid dehydrogenase 1 expression in human fetal membranes: a novel intrauterine source of cortisol. J Clin Endocrinol Metab 88(10):5033–5038. https://doi.org/10.1210/jc.2002-021915

Article  CAS  PubMed  Google Scholar 

Pofi R, Tomlinson JW (2020) Glucocorticoids in pregnancy. Obstet Med 13(2):62–69. https://doi.org/10.1177/1753495X19847832

Article  PubMed  Google Scholar 

Funder JW, Pearce PT, Smith R, Smith AI (1988) Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 242(4878):583–585. https://doi.org/10.1126/science.2845584

Article  PubMed  Google Scholar 

Rajan V, Edwards CR, Seckl JR (1996) 11 beta-hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity. J Neurosci 16(1):65–70

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gomez-Sanchez EP (2014) Brain mineralocorticoid receptors in cognition and cardiovascular homeostasis. Steroids 91:20–31. https://doi.org/10.1016/j.steroids.2014.08.014

Article  CAS  PubMed  PubMed Central  Google Scholar 

De Kloet ER, Vreugdenhil E, Oitzl MS, Joels M (1998) Brain corticosteroid receptor balance in health and disease. Endocr Rev 19(3):269–301. https://doi.org/10.1210/edrv.19.3.0331

Article  PubMed  Google Scholar 

Otte C, Moritz S, Yassouridis A, Koop M, Madrischewski AM, Wiedemann K et al (2007) Blockade of the mineralocorticoid receptor in healthy men: effects on experimentally induced panic symptoms, stress hormones, and cognition. Neuropsychopharmacology 32(1):232–238. https://doi.org/10.1038/sj.npp.1301217

Article  CAS  PubMed  Google Scholar 

Piber D, Schultebraucks K, Mueller SC, Deuter CE, Wingenfeld K, Otte C (2016) Mineralocorticoid receptor stimulation effects on spatial memory in healthy young adults: a study using the virtual Morris Water Maze task. Neurobiol Learn Mem 136:139–146. https://doi.org/10.1016/j.nlm.2016.10.006

Article  CAS  PubMed  Google Scholar 

Lopez JF, Chalmers DT, Little KY, Watson SJ, A.E. Bennett Research Award (1998) Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: implications for the neurobiology of depression. Biol Psychiatry 43(8):547–573. https://doi.org/10.1016/s0006-3223(97)00484-8

Article  CAS  PubMed  Google Scholar 

Veenema AH, Meijer OC, de Kloet ER, Koolhaas JM (2003) Genetic selection for coping style predicts stressor susceptibility. J Neuroendocrinol 15(3):256–267. https://doi.org/10.1046/j.1365-2826.2003.00986.x

Article  CAS  PubMed  Google Scholar 

Qin S, Hermans EJ, van Marle HJ, Luo J, Fernandez G (2009) Acute psychological stress reduces working memory-related activity in the dorsolateral prefrontal cortex. Biol Psychiatry 66(1):25–32. https://doi.org/10.1016/j.biopsych.2009.03.006

Article  PubMed  Google Scholar 

Dias-Ferreira E, Sousa JC, Melo I, Morgado P, Mesquita AR, Cerqueira JJ et al (2009) Chronic stress causes frontostriatal reorganization and affects decision-making. Science 325(5940):621–625. https://doi.org/10.1126/science.1171203

Article  CAS  PubMed  Google Scholar 

Gomez-Sanchez E, Gomez-Sanchez CE (2014) The multifaceted mineralocorticoid receptor. Compr Physiol 4(3):965–994. https://doi.org/10.1002/cphy.c130044

Article  PubMed  PubMed Central  Google Scholar 

Sharma ST, Nieman LK, Feelders RA (2015) Cushing’s syndrome: epidemiology and developments in disease management. Clin Epidemiol 7:281–293. https://doi.org/10.2147/CLEP.S44336

Article  PubMed  PubMed Central  Google Scholar 

Pivonello R, De Martino M, De Leo M, Tauchmanovà L, Faggiano A, Lombardi G et al (2007) Cushing’s syndrome: aftermath of the cure. Arq Bras Endocrinol Metabol 51(8):1381–1391. https://doi.org/10.1590/s0004-27302007000800025

Article  PubMed  Google Scholar 

Scaroni C, Albiger NM, Palmieri S, Iacuaniello D, Graziadio C, Damiani L et al (2020) Approach to patients with pseudo-Cushing’s states. Endocr Connect 9(1):R1–R13. https://doi.org/10.1530/EC-19-0435

Article  PubMed  Google Scholar 

Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR et al (2021) Consensus on diagnosis and management of Cushing’s disease: a guideline update. Lancet Diabetes Endocrinol 9(12):847–875. https://doi.org/10.1016/S2213-8587(21)00235-7

Article  PubMed 

留言 (0)

沒有登入
gif