Paul S.R., Bennett F., Calvetti J.A., Kelleher K., Wood C.R., O’Hara R.M., Jr., Leary A.C., Sibley B., Clark S.C., Williams D.A., Yang Y.C. 1990. Molecular cloning of a cDNA encoding interleukin 11, a stromal cell derived lymphopoietic and hematopoietic cytokine. Proc. Natl. Acad. Sci. USA. 87, 7512–7516.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heese K., Nagai Y., Sawada T. 2000. Induction of rat L-phosphoserine phosphatase by amyloid-beta (1-42) is inhibited by interleukin-11. Neurosci. Lett. 288 (1), 37–40.

Article  CAS  PubMed  Google Scholar 

Guk K.D., Kuprash D.V. (2011) Interleukin-11, a member of the IL-6-like cytokine family. Mol. Biol. (Moscow). 45 (1), 36‒46. https://doi.org/10.1134/S0026893311010055

Article  CAS  Google Scholar 

Wilde M.I., Faulds D. 1998. Oprelvekin: a review of its pharmacology and therapeutic potential in chemotherapy-induced thrombocytopenia. BioDrugs. 10 (2), 159–171.

Article  CAS  PubMed  Google Scholar 

Einarsson O., Geba G.P., Zhu Z., Landry M., Elias J.A. 1996. Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness. J. Clin. Investig. 97 (4), 915–924.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang W., Geba G.P., Zheng T., Ray P., Homer R.J., Kuhn C. 1996. Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction. J. Clin. Investig. 98 (12), 2845–2853.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keller D.C., Du X.X., Srour E.F., Hoffman R., Williams D.A. 1993. Interleukin-11 inhibits adipogenesis and stimulates myelopoiesis in human long-term marrow cultures. Blood. 82 (5), 1428–1435.

Article  CAS  PubMed  Google Scholar 

Mehler M.F., Rozental R., Dougherty M., Spray D.C., Kessler J.A. 1993. Cytokine regulation of neuronal differentiation of hippocampal progenitor cells. Nature. 362 (6415), 62–65.

Article  CAS  PubMed  Google Scholar 

Leng S.X., Elias J.A. 1997. Interleukin-11. Int. J. Biochem. Cell. Biol. 29, 1059–1062.

Article  CAS  PubMed  Google Scholar 

Gurfein B.T., Zhang Y., López C.B. 2009. IL-11 regulates autoimmune demyelination. J. Immunol. 183 (7), 4229–4240.

Article  CAS  PubMed  Google Scholar 

Maheshwari A., Janssens K., Bogie J., Van Den Haute C., Struys T., Lambrichts I., Baekelandt V., Stinissen P., Hendriks J.J., Slaets H., Hellings N. 2013. Local overexpression of interleukin-11 in the central nervous system limits demyelination and enhances remyelination. Mediators Inflamm. 2013, 685317.

Article  PubMed  PubMed Central  Google Scholar 

Zhang B., Zhang H.-X., Shi S.-T., Bai Y.-L., Zhe X., Zhang S.-J., Li Y.-J. 2019. Interleukin-11 treatment protected against cerebral ischemia/reperfusion injury. Biomed. Pharmacother. 115, 108816.

Article  CAS  PubMed  Google Scholar 

Gorshkova E.A., Nedospasov S.A., Shilov E.S. (2016) Evolutionary plasticity of IL-6 family cytokines. Mol. Biol. (Moscow). 50 (6), 918–926. https://doi.org/10.1134/S0026893316060066

Article  CAS  Google Scholar 

McKinley D., Wu Q., Yang-Feng T., Yang Y.C. 1992. Genomic sequence and chromosomal location of human interleukin-11 gene (IL11). Genomics. 13 (3), 814–819.

Article  CAS  PubMed  Google Scholar 

Yang Y.C., Yin T. 1992. Interleukin-11 and its receptor. Biofactors. 4 (1), 15–21.

CAS  PubMed  Google Scholar 

Stephen F.A., Thomas L.M., Alejandro A.S., Jinghui Z., Zheng Z., Webb M., David J.L. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucl. Acids Res. 25, 3389–3402.

Article  Google Scholar 

Barton V., Hall M., Hudson K.R., Heath J.K. 2000. Interleukin-11 signals through the formation of a hexameric receptor complex. J. Biol. Chem. 275 (46), 36197–36203.

Article  CAS  PubMed  Google Scholar 

Knut & Alice Wallenberg Foundation. IL-11. The Human Protein Atlas.

Watanabe D., Yoshimura R., Khalil M., Yoshida K., Kishimoto T., Taga T., Kiyama H. 1996. Characteristic localization of gp130 (the signal-transducing receptor component used in common for IL-6/IL-11/CNTF/LIF/OSM. in the rat brain. Eur. J. Neurosci. 8 (8), 1630–1640.

Article  CAS  PubMed  Google Scholar 

Zhang Y., Chen K., Sloan S.A., Bennett M.L., Scholze A.R., O’Keeffe S., Phatnani H.P., Guarnieri P., C-aneda C., Ruderisch N., Deng S., Liddelow S.A., Zhang C., Daneman R., Maniatis T., Barres B.A., Wu J.Q. 2014. An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J. Neurosci. 34 (36), 11929–11947.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang Y., Sloan S.A., Clarke L.E., Caneda C., Plaza C.A., Blumenthal P.D., Vogel H., Steinberg G.K., Edwards M.S., Li G., Duncan J.A., Cheshier S.H., Shuer L.M., Chang E.F., Grant G.A., Gephart M.G., Barres B.A. 2016. Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse. Neuron. 89 (1), 37–53.

Article  CAS  PubMed  Google Scholar 

Barton V., Hudson K.R., Heath J.K. 1999. Identification of three distinct receptor binding sites of murine interleukin-11. J. Biol. Chem. 274 (9), 5755–5761.

Article  CAS  PubMed  Google Scholar 

Tacken I., Dahmen H., Boisteau O., Minvielle S., Jacques Y., Grötzinger J. 1999. Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis. Eur. J. Biochem. 265 (2), 645–655.

Article  CAS  PubMed  Google Scholar 

Metcalfe R.D., Aizel K., Zlatic C.O., Nguyen P.M., Morton C.J., Lio. 2020. The structure of the extracellular domains of human interleukin 11 α-receptor reveals mechanisms of cytokine engagement. J. Biol. Chem. 295 (24), 8285–8301.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lokau J., Agthe M., Flynn C.M., Garbers C. 2017. Proteolytic control of interleukin-11 and interleukin-6 biology. Biochim. Biophys. Acta Mol. Cell. Res. 1864 (11 Pt B), 2105–2117.

Montero A.J., Estrov Z., Freireich E.J., Khouri I.F., Koller C.A., Kurzrock R. 2006. Phase II study of low dose interleukin 11 in patients with myelodysplastic syndrome. Leuk. Lymphoma. 47, 2049–2054.

Article  CAS  PubMed  Google Scholar 

Hatae M., Ariyoshi Y., Fukuoka M., Furuse K., Noda K., Hirabayashi K., Yakushiji M., Ogawa M., Takaku F. 2005. An early phase II clinical study of YM 294 (rhlL 11) in patients with solid tumors and malignant lymphoma. Gan To Kagaku Ryoho. 32, 489–496.

PubMed  Google Scholar 

Hatae M., Noda K., Yamamoto K., Ozaki M., Hiraba yashi K., Nishida T., Ohashi Y., Ogawa M., Takaku F. 2005. A clinical study of YM 294 (rhlL 11) in patients with gynecologic cancer. Gan To Kagaku Ryoho. 32, 479–487.

PubMed  Google Scholar 

Zhang Y., Taveggia C., Melendez-Vasquez C., Einheber S., Raine C.S., Salzer J.L., Brosnan C.F., John G.R. 2006. Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J. Neurosci. 26 (47), 12174–12185.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang X., Tao Y., Chopra M., Dujmovic-Basuroski I., Jin J., Tang Y., Drulovic J., Markovic-Plese S. 2015. IL-11 induces Th17 cell responses in patients with early relapsing-remitting multiple sclerosis. J. Immunol. 194 (11), 5139–5149.

Article  CAS  PubMed  Google Scholar 

Trepicchio W.L., Wang L., Bozza M., Dorner A.J. 1997. IL-11 regulates macrophage effector function through the inhibition of nuclear factor-κB. J. Immunol. 159 (11), 5661–5670.

Article  CAS  PubMed  Google Scholar 

Leng S.X., Elias J.A. 1997. Interleukin-11 inhibits macrophage interleukin-12 production. J. Immunol. 159 (5), 2161–2168.

Article  CAS  PubMed  Google Scholar 

Sreenivasan L., Li L.V., Leclair P., Lim C.J. 2022. Targeting the gp130/STAT3 axis attenuates tumor microenvironment mediated chemoresistance in group 3 medulloblastoma cells. Cells. 11, 381.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Airapetov M., Eresko S., Lebedev A., Bychkov E., Shabanov P. 2021. The role of Toll-like receptors in neurobiology of alcoholism. BioSci. Trends. 15 (2), 74–82.

Article  CAS  PubMed  Google Scholar 

Peterson P.K., Toborek M. 2014. Neuroinflammation Neurodegeneration. New York: Springer.

Book  Google Scholar