Cavalcante MB, Cavalcante C, Sarno M, Barini R. Intrauterine perfusion immunotherapies in recurrent implantation failures: systematic review. Am J Reprod Immunol. 2020;83:e13242.

Article  PubMed  Google Scholar 

Demetri GD, Griffin JD. Granulocyte colony-stimulating factor and its receptor. Blood. 1991;78:2791–808.

Article  CAS  PubMed  Google Scholar 

Metcalf D. The granulocyte-macrophage colony-stimulating factors. Science. 1985;229:16–22.

Article  CAS  PubMed  Google Scholar 

Nagata S, Tsuchiya M, Asano S, Kaziro Y, Yamazaki T, Yamamoto O, et al. Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor. Nature. 1986;319:415–8.

Article  CAS  PubMed  Google Scholar 

Bonilla MA, Gillio AP, Ruggeiro M, Kernan NA, Brochstein JA, Abboud M, et al. Effects of recombinant human granulocyte colony-stimulating factor on neutropenia in patients with congenital agranulocytosis. N Engl J Med. 1989;320:1574–80.

Article  CAS  PubMed  Google Scholar 

Tabbara IA, Ghazal CD, Ghazal HH. The role of granulocyte colony-stimulating factor in hematopoietic stem cell transplantation. Cancer Investig. 1997;15:353–7.

Article  CAS  Google Scholar 

Lédée N, Gridelet V, Ravet S, Jouan C, Gaspard O, Wenders F, et al. Impact of follicular G-CSF quantification on subsequent embryo transfer decisions: a proof of concept study. Hum Reprod. 2013;28:406–13.

Article  PubMed  Google Scholar 

Kamath MS, Kirubakaran R, Sunkara SK. Granulocyte-colony stimulating factor administration for subfertile women undergoing assisted reproduction. Cochrane Database Syst Rev. 2020;1:Cd013226.

PubMed  Google Scholar 

Zhang L, Xu WH, Fu XH, Huang QX, Guo XY, Zhang L, et al. Therapeutic role of granulocyte colony-stimulating factor (G-CSF) for infertile women under in vitro fertilization and embryo transfer (IVF-ET) treatment: a meta-analysis. Arch Gynecol Obstet. 2018;298:861–71.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Busnelli A, Somigliana E, Cirillo F, Baggiani A, Levi-Setti PE. Efficacy of therapies and interventions for repeated embryo implantation failure: a systematic review and meta-analysis. Sci Rep. 2021;11:1747.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Achilli C, Duran-Retamal M, Saab W, Serhal P, Seshadri S. The role of immunotherapy in in vitro fertilization and recurrent pregnancy loss: a systematic review and meta-analysis. Fertil Steril. 2018;110:1089–100.

Article  CAS  PubMed  Google Scholar 

Li J, Mo S, Chen Y. The effect of G-CSF on infertile women undergoing IVF treatment: a meta-analysis. Syst Biol Reprod Med. 2017;63:239–47.

Article  PubMed  Google Scholar 

Xie Y, Zhang T, Tian Z, Zhang J, Wang W, Zhang H, et al. Efficacy of intrauterine perfusion of granulocyte colony-stimulating factor (G-CSF) for infertile women with thin endometrium: a systematic review and meta-analysis. Am J Reprod Immunol. 2017;78:1–10.

Article  Google Scholar 

Cavalcante MB, Costa Fda S, Barini R, Araujo Júnior E. Granulocyte colony-stimulating factor and reproductive medicine: a review. Iran J Reprod Med. 2015;13:195–202.

PubMed  PubMed Central  Google Scholar 

Robert CA, Abbas MK, Zaidi ARZ, Thiha S, Malik BH. Mediator in the embryo-endometrium cross-talk: granulocyte Colony-stimulating factor in infertility. Cureus. 2019;11:e5390.

PubMed  PubMed Central  Google Scholar 

Eftekhar M, Naghshineh E, Khani P. Role of granulocyte colony-stimulating factor in human reproduction. J Res Med Sci. 2018;23:7.

Article  PubMed  PubMed Central  Google Scholar 

Jiang Y, Zhao Q, Zhang Y, Zhou L, Lin J, Chen Y, et al. Treatment of G-CSF in unexplained, repeated implantation failure: a systematic review and meta-analysis. J Gynecol Obstet Hum Reprod. 2020;49:101866.

Mouhayar Y, Sharara FI. G-CSF and stem cell therapy for the treatment of refractory thin lining in assisted reproductive technology. J Assist Reprod Genet. 2017;34:831–7.

Article  PubMed  PubMed Central  Google Scholar 

Rocha MNC, Florêncio RS, Alves RRF. The role played by granulocyte colony stimulating factor (G-CSF) on women submitted to in vitro fertilization associated with thin endometrium: systematic review. JBRA Assist Reprod. 2020;24:278–82.

PubMed  PubMed Central  Google Scholar 

Shah J, Welsh SJ. The clinical use of granulocyte-colony stimulating factor. Br J Hosp Med (Lond). 2014;75:C29–32.

Article  PubMed  Google Scholar 

Toth B, Würfel W, Germeyer A, Hirv K, Makrigiannakis A, Strowitzki T. Disorders of implantation--are there diagnostic and therapeutic options? J Reprod Immunol. 2011;90:117–23.

Article  CAS  PubMed  Google Scholar 

Würfel W. Treatment with granulocyte colony-stimulating factor in patients with repetitive implantation failures and/or recurrent spontaneous abortions. J Reprod Immunol. 2015;108:123–35.

Article  PubMed  Google Scholar 

Zhao J, Xu B, Xie S, Zhang Q, Li YP. Whether G-CSF administration has beneficial effect on the outcome after assisted reproductive technology? A systematic review and meta-analysis. Reprod Biol Endocrinol. 2016;14:62.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lebovitz O, Orvieto R. Treating patients with "thin" endometrium - an ongoing challenge. Gynecol Endocrinol. 2014;30:409–14.

Article  CAS  PubMed  Google Scholar 

Mekinian A, Cohen J, Alijotas-Reig J, Carbillon L, Nicaise-Roland P, Kayem G, et al. Unexplained recurrent miscarriage and recurrent implantation failure: is there a place for immunomodulation? Am J Reprod Immunol. 2016;76:8–28.

Article  CAS  PubMed  Google Scholar 

Turocy J, Williams Z. Novel therapeutic options for treatment of recurrent implantation failure. Fertil Steril. 2021;116:1449–54.

Article  CAS  PubMed  Google Scholar 

Hou Z, Jiang F, Yang J, Liu Y, Zha H, Yang X, et al. What is the impact of granulocyte colony-stimulating factor (G-CSF) in subcutaneous injection or intrauterine infusion and during both the fresh and frozen embryo transfer cycles on recurrent implantation failure: a systematic review and meta-analysis? Reprod Biol Endocrinol. 2021;19:125.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kamath MS, Chittawar PB, Kirubakaran R, Mascarenhas M. Use of granulocyte-colony stimulating factor in assisted reproductive technology: a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2017;214:16–24.

Article  CAS  PubMed  Google Scholar 

Zeyneloglu HB, Onalan G. Remedies for recurrent implantation failure. Semin Reprod Med. 2014;32:297–305.

Article  PubMed  Google Scholar 

Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. Bmj. 2021;372:n160.

Article  PubMed  PubMed Central  Google Scholar 

Barad DH, Yu Y, Kushnir VA, Shohat-Tal A, Lazzaroni E, Lee HJ, et al. A randomized clinical trial of endometrial perfusion with granulocyte colony-stimulating factor in in vitro fertilization cycles: impact on endometrial thickness and clinical pregnancy rates. Fertil Steril. 2014;101:710–5.

Article  CAS  PubMed  Google Scholar 

Eftekhar M, Hosseinisadat R, Baradaran R, Naghshineh E. Effect of granulocyte colony stimulating factor (G-CSF) on IVF outcomes in infertile women: an RCT. Int J Reprod Biomed. 2016;14:341–6.

CAS  PubMed  PubMed Central  Google Scholar 

Jain S, Mahey R, Malhotra N, Kalaivani M, Sangeeta P, Bhatt A, et al. Effect of intrauterine perfusion of granulocyte Colony-stimulating factor on endometrial parameters and in vitro fertilization outcome in women undergoing in vitro fertilization/intracytoplasmic sperm injection cycles: a randomized controlled trial. J Hum Reprod Sci. 2018;11:254–60.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sarvi F, Arabahmadi M, Alleyassin A, Aghahosseini M, Ghasemi M. Effect of increased endometrial thickness and implantation rate by granulocyte Colony-stimulating factor on unresponsive thin endometrium in fresh in vitro fertilization cycles: a randomized clinical trial. Obstet Gynecol Int. 2017;2017:3596079.

Article  PubMed  PubMed Central  Google Scholar 

Aleyasin A, Abediasl Z, Nazari A, Sheikh M. Granulocyte colony-stimulating factor in repeated IVF failure, a randomized trial. Reproduction. 2016;151:637–42.

Article  CAS  PubMed  Google Scholar 

Arefi S, Fazeli E, Esfahani M, Borhani N, Yamini N, Hosseini A, et al. Granulocyte-colony stimulating factor may improve pregnancy outcome in patients with history of unexplained recurrent implantation failure: an RCT. Int J Reprod Biomed. 2018;16:299–304.

CAS  PubMed  PubMed Central  Google Scholar 

Davari-Tanha F, Shahrokh Tehraninejad E, Ghazi M, Shahraki Z. The role of G-CSF in recurrent implantation failure: a randomized double blind placebo control trial. Int J Reprod Biomed. 2016;14:737–42.

PubMed  PubMed Central  Google Scholar 

Eftekhar M, Miraj S, Farid Mojtahedi M, Neghab N. Efficacy of intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: a randomized control trial. Int J Reprod Biomed. 2