The role of macrophages in the tumor microenvironment and tumor metabolism

Vitale I, Manic G, Coussens LM, Kroemer G, Galluzzi L (2019) Macrophages and metabolism in the tumor microenvironment. Cell Metab 30(1):36–50

Article  CAS  PubMed  Google Scholar 

Quail DF, Joyce JA (2013) Microenvironmental regulation of tumor progression and metastasis. Nat Med 19(11):1423–1437

Article  CAS  PubMed  PubMed Central  Google Scholar 

Christofides A, Strauss L, Yeo A, Cao C, Charest A, Boussiotis VA (2022) The complex role of tumor-infiltrating macrophages. Nat Immunol 23(8):1148–1156

Article  CAS  PubMed  Google Scholar 

Xiang X, Wang J, Lu D, Xu X (2021) Targeting tumor-associated macrophages to synergize tumor immunotherapy. Signal Transduct Target Ther 6(1):75

Article  PubMed  PubMed Central  Google Scholar 

Fu LQ, Du WL, Cai MH, Yao JY, Zhao YY, Mou XZ (2020) The roles of tumor-associated macrophages in tumor angiogenesis and metastasis. Cell Immunol 353:104119

Article  CAS  PubMed  Google Scholar 

Dehne N, Mora J, Namgaladze D, Weigert A, Brüne B (2017) Cancer cell and macrophage cross-talk in the tumor microenvironment. Curr Opin Pharmacol 35:12–19

Article  CAS  PubMed  Google Scholar 

Wu K, Lin K, Li X, Yuan X, Xu P, Ni P et al (2020) Redefining tumor-associated macrophage subpopulations and functions in the tumor microenvironment. Front Immunol 11:1731

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hinshaw DC, Shevde LA (2019) The tumor microenvironment innately modulates cancer progression. Cancer Res 79(18):4557–4566

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li S, Yu J, Huber A, Kryczek I, Wang Z, Jiang L et al (2022) Metabolism drives macrophage heterogeneity in the tumor microenvironment. Cell Rep 39(1):110609

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pan Y, Yu Y, Wang X, Zhang T (2020) Tumor-associated macrophages in tumor immunity. Front Immunol 11:583084

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nakamura K, Smyth MJ (2020) Myeloid immunosuppression and immune checkpoints in the tumor microenvironment. Cell Mol Immunol 17(1):1–12

Article  CAS  PubMed  Google Scholar 

Tamura R, Tanaka T, Yamamoto Y, Akasaki Y, Sasaki H (2018) Dual role of macrophage in tumor immunity. Immunotherapy 10(10):899–909

Article  CAS  PubMed  Google Scholar 

Lechner M, Lirk P, Rieder J (2005) Inducible nitric oxide synthase (iNOS) in tumor biology: the two sides of the same coin. Semin Cancer Biol 15(4):277–289

Article  CAS  PubMed  Google Scholar 

Wu T, Yang W, Sun A, Wei Z, Lin Q (2023) The Role of CXC Chemokines in Cancer Progression. Cancers 15(1):167

Kashfi K, Kannikal J, Nath N (2021) Macrophage reprogramming and cancer therapeutics: Role of iNOS-derived NO. Cells 10(11):3194

Zhou X, Liu Q, Wang X, Yao X, Zhang B, Wu J et al (2023) Exosomal ncRNAs facilitate interactive ‘dialogue’ between tumor cells and tumor-associated macrophages. Cancer Lett 552:215975

Article  CAS  PubMed  Google Scholar 

Boutilier AJ, Elsawa SF (2021) Macrophage polarization states in the tumor microenvironment. Int J Mol Sci 22(13):6995

Mantovani A, Marchesi F, Malesci A, Laghi L, Allavena P (2017) Tumour-associated macrophages as treatment targets in oncology. Nat Rev Clin Oncol 14(7):399–416

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mills CD, Lenz LL, Harris RA (2016) A breakthrough: macrophage-directed cancer immunotherapy. Cancer Res 76(3):513–516

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23(11):549–555

Article  CAS  PubMed  Google Scholar 

Mantovani A, Marchesi F, Malesci A, Laghi L, Allavena P (2017) Tumour-associated macrophages as treatment targets in oncology. Nat Rev Clin Oncol 14(7):399–416

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elinav E, Nowarski R, Thaiss CA, Hu B, Jin C, Flavell RA (2013) Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer 13(11):759–771

Article  CAS  PubMed  Google Scholar 

DeNardo DG, Ruffell B (2019) Macrophages as regulators of tumour immunity and immunotherapy. Nat Rev Immunol 19(6):369–382

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mantovani A, Allavena P, Sica A, Balkwill F (2008) Cancer-related inflammation. Nature 454(7203):436–444

Article  CAS  PubMed  Google Scholar 

Candido J, Hagemann T (2013) Cancer-related inflammation. J Clin Immunol 33(Suppl 1):S79-84

Article  PubMed  Google Scholar 

Qu X, Tang Y, Hua S (2018) Immunological approaches towards cancer and inflammation: a cross talk. Front Immunol 9:563

Article  PubMed  PubMed Central  Google Scholar 

Tang X (2013) Tumor-associated macrophages as potential diagnostic and prognostic biomarkers in breast cancer. Cancer Lett 332(1):3–10

Article  CAS  PubMed  Google Scholar 

Cassetta L, Pollard JW (2018) Targeting macrophages: therapeutic approaches in cancer. Nat Rev Drug Discov 17(12):887–904

Article  CAS  PubMed  Google Scholar 

Locati M, Curtale G, Mantovani A (2020) Diversity, mechanisms, and significance of macrophage plasticity. Annu Rev Pathol 15:123–147

Article  CAS  PubMed  Google Scholar 

Rigoni TS, Vellozo NS, Guimarães-Pinto K, Cabral-Piccin M, Fabiano-Coelho L, Matos-Silva TC et al (2022) Axl receptor induces efferocytosis, dampens M1 macrophage responses and promotes heart pathology in Trypanosoma cruzi infection. Commun Biol 5(1):1421

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nakagawa M, Karim MR, Izawa T, Kuwamura M, Yamate J (2021) Immunophenotypical characterization of M1/M2 macrophages and lymphocytes in cisplatin-induced rat progressive renal fibrosis. Cells 10(2):257

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yunna C, Mengru H, Lei W, Weidong C (2020) Macrophage M1/M2 polarization. Eur J Pharmacol 877:173090

Article  PubMed  Google Scholar 

Kerneur C, Cano CE, Olive D (2022) Major pathways involved in macrophage polarization in cancer. Front Immunol 13:1026954

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou J, Tang Z, Gao S, Li C, Feng Y, Zhou X (2020) Tumor-associated macrophages: recent insights and therapies. Front Oncol 10:188

Article  PubMed  PubMed Central  Google Scholar 

Schweer D, McAtee A, Neupane K, Richards C, Ueland F, Kolesar J (2022) Tumor-associated macrophages and ovarian cancer: implications for therapy. Cancers (Basel) 14(9):2220

Brown JM, Recht L, Strober S (2017) The promise of targeting macrophages in cancer therapy. Clin Cancer Res 23(13):3241–3250

Article  PubMed  PubMed Central  Google Scholar 

Pathria P, Louis TL, Varner JA (2019) Targeting tumor-associated macrophages in cancer. Trends Immunol 40(4):310–327

Article  CAS  PubMed  Google Scholar 

Li X, Liu R, Su X, Pan Y, Han X, Shao C et al (2019) Harnessing tumor-associated macrophages as aids for cancer immunotherapy. Mol Cancer 18(1):177

Article  PubMed  PubMed Central  Google Scholar 

Zhang SY, Song XY, Li Y, Ye LL, Zhou Q, Yang WB (2020) Tumor-associated macrophages: a promising target for a cancer immunotherapeutic strategy. Pharmacol Res 161:105111

Article  CAS  PubMed  Google Scholar 

Laviron M, Boissonnas A (2019) Ontogeny of tumor-associated macrophages. Front Immunol 10:1799

Article  CAS 

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